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Doctor insights on: Nitrofurantoin With Trimethoprim

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Are nitrofurantoin and trimethoprim the same?

Are nitrofurantoin and trimethoprim the same?

No: They both work completely differently - trimethoprim is an antibiotic and nitrofurantoin is something that works more simply, such that we call it a urinary antiseptic. ...Read more

Dr. Jerome Zacks
329 Doctors shared insights

Nitrofurantoin (Definition)

Nitrofurantoin is an antibiotic which is marketed under the following brand names; niftran, furadantin, (nitrofurantoin) furabid, macrobid, macrodantin, nitrofur mac, nitro macro, nifty-sr, martifur-mr, uro-tablinen or nifuretten (in germany), martifur-100 (in india), urantoin, nifuran (in macedonia) and uvamin (in middle east). It is usually used in treating urinary tract infection. It is often ...Read more


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I was diagnosed with a uti. .. no symptoms. I was prescribed nitrofurantoin and bactrim (sulfamethoxazole and trimethoprim). Both bad side effects. Can I do something without taking meds?

I was diagnosed with a uti. .. no symptoms. I was prescribed nitrofurantoin and bactrim (sulfamethoxazole and trimethoprim). Both bad side effects. Can I do something without taking meds?

Call your doctor: The most common side effect of these drugs is allergic skin rash, especially with Bactrim; I would be suspicious that any other symptoms are not actual drug side effects. But even 2-3 days treatment sometimes is enough for UTI. If you need additional Rx and truly cannot tolerate either of these drugs, several other antibiotics would work. Contact your doctor and follow his or her advice about it. ...Read more

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Does trimethoprim work faster than macrodantin (nitrofurantoin) for a uti?

Does trimethoprim work faster than macrodantin (nitrofurantoin) for a uti?

No: The antibiotic that works the best is the one to which the bacteria is sensitive. If the bacteria is sensitive to both Macrodantin (nitrofurantoin) and trimethoprim, then they should work equally well. ...Read more

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I've got a urine tract and been given trimethoprim and nitrofurantoin and it still hasn't gone and it going to be tested in hospital. What can it be?

I've got a urine tract and been given trimethoprim and nitrofurantoin and it still hasn't gone and it going to be tested in hospital. What can it be?

Urine Culture?: I imagine by now your doctor has done a urine culture. That should show exactly what the bacteria is causing the infections, and what antibiotics it is sensitive to. ...Read more

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I have taken macrobid, bactrim, (sulfamethoxazole and trimethoprim) nitrofum and other meds that have failed with my chronic uti. Should I be taking something else or could I be misdiagnosed?

Recurrent UTI's: Has a urine culture been done to determine what bacteria are causing the infections? Culture is accompanied by sensitivity testing to decide which antibiotic works best against the bacteria? Are you diabetic? Do you drink a lot of pop? You may have interstitial cystitis, which affects the bladder lining. See a urologist for a thorough work-up and treatment. ...Read more

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60yrs UTI. Bactrim, (sulfamethoxazole and trimethoprim) Macrobid day2 of 7 Waiting4culture. Still some mild pelvic&back pain. Still UTI? What else? Please be specific

60yrs UTI. Bactrim, (sulfamethoxazole and trimethoprim) Macrobid day2 of 7 Waiting4culture. Still some mild pelvic&back pain. Still UTI? What else? Please be specific

UTI: Give it more time...2 days is barely enough time to get antibiotic levels up to a steady level. The pelvic and back pain should subside...but keep your primary or GYN in the loop in case the antibiotics need changing later or symptoms don't go away. Drink cranberry juice...it contains proteins that inhibit bacterial binding in the bladder. ...Read more

Dr. Tony Ho Dr. Ho
1 doctor agreed:
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My kidneyhad been hurting, and had a culture and put on bactrim, (sulfamethoxazole and trimethoprim) no good then on Macrobid stillhave pain. No fever, is it a kidney inf and not uti? Both?

Dr. Tony Ho Dr. Ho
1 doctor agreed:
My kidneyhad been hurting, and had a culture and put on bactrim, (sulfamethoxazole and trimethoprim) no good then on Macrobid stillhave pain. No fever, is it a kidney inf and not uti? Both?

Maybe: Kidney infections are usually the result of a UTI that has climbed up the urinary tract to the kidney. Macrobid is not appropriate for a kidney infection. If you are having persistent symptoms despite treatment, I would definitely see your doctor or go to an urgent care; they will likely need to do imaging to see if you have a stone or abscess associated with this. Good luck! ...Read more

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If I'm allergic to nitrofurantoin, is it likely i'd be allergic to cipro (ciprofloxacin) also?

If I'm allergic to nitrofurantoin, is it likely i'd be allergic to cipro (ciprofloxacin) also?

Not likely: The two have no relationship to one another. Some studies in the drug literature have found that people who have an allergic response to one drug are likely to have an allergic response - randomly - to another, even though it's chemically unrelated. But that's just a function of the fact that those individuals have hyperactive/hyperresponsive immune systems. There's no predicting who and which. ...Read more

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I'm taking Nitrofurantoin Mono-MCR 100MG. For an UTI. How long before I can expect some relief from the UTI symptoms?

See below: If UTI diagnosis correct and bacteria sensitive to nitrofurantoin which is very good choice of antibiotic for simple UTIs/bladder infections without fever, then your may notice improvement in symptoms as soon as 24 hrs if treatment initiated soon after symptom onset or may take 48-72 hrs if symptoms and inflammation have been present for several days or longer. Should take Nitrofurantoin 5-7 days. ...Read more

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The doctor gave me nitrofurantoin 100mg for 3 days 2 a day I'm due to take my last tablet tonight but I'm in a lot of pain still?

See below: I assume you have a urinary tract infection. Nitrofurantoin is only a urinary antiseptic it does not achieve therapeutic levels in tissues so if you have a tissue invasive infection it will be ineffective. It has a lot of serious toxic side effects and I try not to use it if I have any other alternative antibiotics that will be effective. Get your doctor to prescribe a tissue active antibiotic. ...Read more

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What is macrodantin (nitrofurantoin) used for?

What is macrodantin (nitrofurantoin) used for?

UTIs: This antibiotic can be used to treat several infections, but it is an important drug for the urinary tract. It is an effective agent to prevent infections in patients at risk of recurrent urinary infections. ...Read more

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Please describe the medication: nitrofurantoin?

Please describe the medication: nitrofurantoin?

Macrobid: Nitrofurantoin is an antibiotic which is marketed under the following brand names; niftran, furadantin, (nitrofurantoin) furabid, macrobid, macrodantin, nitrofur mac, nitro macro, nifty-sr, martifur-mr, uro-tablinen or nifuretten (in germany), martifur-100 (in india), urantoin, nifuran (in macedonia) and uvamin (in middle east). It is usually used in treating urinary tract infection. It is often used against e. Co. ...Read more

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Could liquid nitrofurantoin be taken rectally?

Nitrofurantoin: Nitrofurantoin comes in suppository form - don't know of any liquid that goes in the rectum. ...Read more

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I started taking nitrofurantoin Marco 100 mg and now I'm starting to bleed. Should I stop taking them?

I started taking nitrofurantoin Marco 100 mg and now I'm starting to bleed. Should I stop taking them?

Talk to: Your prescriber. It is important to discuss with your doctor before starting any medication ...Read more

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Side effects of nitrofurantoin taken for uti?

Side effects of nitrofurantoin taken for uti?

Many: This antiseptic has close chemical similarity to diphenylhydantoin (dilantin), a drug with enough side effects to fill an entire textbook. Taken for brief periods this can be a highly effective agent against simple urinary tract infection, but would advise against long-term usage in most circumstances. ...Read more

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What is the treatment for nitrofurantoin overdose?

What is the treatment for nitrofurantoin overdose?

Usually supportive: Treatment for a nitorfur overdose will vary. If the overdose was recent, the healthcare provider may administer certain medicines or place a tube into the stomach to "pump the stomach." treatment also involves supportive care, which consists of treating the symptoms that occur as a result of the overdose. For example, supportive treatment options may include:


fluids through an intravenous l. ...Read more

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Which is safer? Nitrofurantoin or cipro (ciprofloxacin)?

Which is safer? Nitrofurantoin or cipro (ciprofloxacin)?

About same, but...: Both are very safe; the frequency of serious adverse reactions is probably about the same. However, nitrofurantoin is less likely to make your body's bacteria resistant to antibiotics, making it harder to treat future infections. Assuming you're being treated for a urinary infection, nitrofurantoin is preferred if active against the bacteria causing it. Discuss with your doctor. ...Read more

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Would long term use of nitrofurantoin affect my periods?

Nitrofurantoin: I was unable to find this listed as a side effect of Nitrofurantoin. ...Read more

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Can I treat a 3-month old UTI with macrodantin (nitrofurantoin)?

Can I treat a 3-month old UTI with macrodantin (nitrofurantoin)?

No unless prescribed: A 3 month old with a urinary tract infection is something that can be serious and may be treated as an inpatient depending on the infection and if there are undetected anomalies with the urinary tract itself.
Never diagnose it yourself, have thebabu checked asap. ...Read more

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Can you mix nitrofurantoin and levofloxacin or are they antagonists?

Can you mix nitrofurantoin and levofloxacin or are they antagonists?

You *may*, but. ..: The only time I would see using these at the same time is in the unfortunate circumstance that you were treating a urinary tract infection with the nitrofurantoin and a different infection with the levofloxacin - a highly unlikely circumstance. There's no reason to be using the two together to be treating the same infection. When it comes to antibacterials, never ever use more than you need. ...Read more

Dr. Edward Kuhnley
143 Doctors shared insights

Trimethoprim (Definition)

Trimethoprim is ...Read more


Dr. Shari Jackson
148 Doctors shared insights

Macrodantin (Definition)

Macrodantin is ...Read more