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No data yet...: Gleevec (imatinib) inhibits a number of tyrosine kinases in cells (c-kit, pdgfralpha, c-abl) . There is very recent data that Gleevec (imatinib) may have activity in retinoblastoma, but these experiments where done on isolated retinoblastoma cells grown in culture. There are no clinical trials showing that Gleevec (imatinib) can treat retinoblastoma. Future clinical trials may be planned to address this question. ...Read moreSee 1 more doctor answer
I have cml. I take 600 mg tasigna-nilotinib daily, and4000 mg vit c per day and 5000iu vit d3. Is it safe to take as much? My doc says yes.
Vitamins: Vitamins a, d, e, & k are fat soluble vitamins and so too much supplement can lead to toxic levels. Vitamin c is water soluble and so excess can be eliminated in the urine. Your likely ok taking the vit d due to your ongoing treatment. However, your physician should check your level every 6 to 12 months to insure the level is optimal and not a risk. ...Read more
While gefitinib was: Developed first, it is hard to find in america (iressa (gefitinib)). Erlotinib (tarceva) has more side effects, but a trial showed a survival advantage. Probably more related to the characteristics of the study participants than the drug. These are small molecule, tyrosine kinase inhibitors in the erb family of receptors. Canada and europe has iressa (gefitinib). Erlotinib is in us. ...Read moreSee 1 more doctor answer
Targeted therapy: It is a targeted therapy. It is an oral tyrosine kinase inhibitor pill that targets part of the egfr pathway. Recently we have learned that there a several gene mutations that are found in lung cancer. If a patient has a mutation of the egfr system that their lung cancer developed, this drug can be more effective than chemotherapy in controlling their cancer. ...Read more
Erlotinib: Technical: inhibitor of the thyrosine kinase activity of egfr. King's english: oral medication in the category of targeted therapies that interferes with the molecular mechanisms that make cancer cells grow. The idea is to cause damage to the cancer cell with minimal collateral damage to normal cells. Currently approved for treatment of lung cancer and pancreatic cancer too if i'm not mistaken. ...Read more
Yes, for Stage 4: Nexavar, or sorafenib, is used to treat advanced, unresectable hepatocellular carcinoma. It is also used to treat patients with advanced kidney cancer. This drug is a multikinase inhibitor and works by decreasing tumor growth and replication, by inhibiting the formation of blood vessels that tumors rely on to get nourishment. This is not a curative treatment, prolonging survival on average 7 mo. ...Read more
Cancer: Specifically lung cancer, but perhaps others, in which a specific mutation is present. For now it is only used for people with metastatic lung cancer, but some other forms of cancer in which specific activating egfr mutations are present. For those with the proper activating mutations, it is very effective, but the response typically does not last. Tumors evolve the means to adapt to the drug. ...Read more
Diagnoged with cutaneous tcell lymphoma nhl.Treated with eletron beam.Interferon, gemcitabine, anthracycline, etoposide, procarbazine.Nodules over body .?
Gem for taxotere (docetaxel): Short answer is no. It cannot be substituted. Now depending upon the underlying cancer whether lung, breast, pancreatic or any other primary solid tumor, one can use taxol, Abraxane or Navelbine (vinorelbine) (they are taxanes like taxotere). If we want to move to a different agent altogether, then Gemzar or a no of other drugs would be available depending upon what the primary tumor is. ...Read more
2 versions 1 drug: They are the same drug except that the pegylation makes that drug longer acting, so it can be given less often. ...Read more