Doctor insights on:
A few days: With these kinds of calcium channel blockers, it is not usually recommended that they be discontinued rapidly or at once. Tapering the dose down over a week can reduce the "rebound" symptoms - it is not truly a "withdrawal," in the usual sense. If stopped abruptly, I have seen symptoms go on for a week, but they are usually only noticeable for 3-4 days. ...Read more
Don't stop abruptly: Stopping calcium channel blockers, particularly Nifedipine suddenly can not only cause withdrawal or "rebound" symptoms, it can dangerously elevate blood pressure and pulse to where it can cause harm. They should be tapered, or if you had a bad reaction, switched to another similar drug and that be tapered gradually. ...Read more
If yes, what are withdrawal symptoms of Procardia (nifedipine) other than possible rise in BP? Thank you.
Unlikely : BP may increase, but generally it does not cause the rebound effect (oral version of this drug). You may get headaches and chest tightness. Symptoms are from over expression of the receptor for this calcium channel blocker and are brief in duration. It also depends about indication (htn, premature labor, etc) ...Read more
Ca++ channel blocker: The cause of edema in calcium channel blocker medications is due to the decrease in arteriolar resistance. The resistance change is not seen in the veins, so the pressure in the capillary beds is increased, thus causing fluid fluid shift into the tissues, resulting in edema. ...Read more
Approximately: 5 hours for Isosorbide Mononitrate used for prevention of angina pectoris due to coronary heart disease, HTN and MI. It is a vasodilatory agent that dilates the blood vessels. It lowers blood pressure and reduces the left ventricular preload and after load reducing the hearts oxygen requirement. Nifedipine 1/2 life 2 hours. Calcium channel blocker. Go to Medscape or Drugbank for more info. ...Read more
Check your BP: I assume taking for hypertension, if you think you missed a dose, could check your blood pressure, if it is high, SBP > 140 or 150, probably could take a dose now. If your BP is OK, then wait til tomorrow and resume as usual. Perhaps a pillbox or a smartphone app may help you with med compliance in the future. ...Read more