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Doctor insights on: Nifedipine Diabetes Related Agent

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What do you find to be typical progression of drugs in type 2 diabetes (ie, start on metformin, but will need to add another agent after x months, etc?

What do you find to be typical progression of drugs in type 2 diabetes (ie, start on metformin, but will need to add another agent after x months, etc?

Many possible: Although metformin is the typical starting medication for most type 2 diabetics, many times it is not adequate alone to control sugars. Additional medications are based on many factors including: how high is your hemoglobin a1c, your weight, your age, other factors like heart, liver, and kidney function, cost factors. A typical next class of drugs would be a dpp-iv inhibitor or glp-1 agonist. ...Read more

Dr. Quang Nguyen
3,145 doctors shared insights

Diabetes (Definition)

Presistent increased frequency of emptying bladder, urinating, as a symptom of a disease state. 2 types: Mellitus (high blood glucose) & Insipidus (inadequate anti-diuretic hormone). In Diabetes mellitus, the far more common, glucose concentrations are ↑ed due to combination of 8 organ system changes referred to as the "ominous octet" & aggravated by intake of sugars (simple & complex ...Read more


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I was in vietnam and have heart/blood pressure/diabetes problems. What else is caused by agent orange?

I was in vietnam and have heart/blood pressure/diabetes problems. What else is caused by agent orange?

Agent orange: It has been hard to pin down the effects of agent orange. To be sure, it is nasty stuff, but many of the "effects", such as heart, BP, diabetes, are very common in Viet Nam era veterans, regardless of exposure. Hopefully, you're getting treatment for these conditions. ...Read more

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Can my undifferentiated connective tissue disease be generated by my fathers severe exposure to agent orange? He has type 2 diabetes due to exposure.

Can my undifferentiated connective tissue disease be generated by my fathers severe exposure to agent orange? He has type 2 diabetes due to exposure.

Not likely.: The Institute of Medicine publishes a biennial report on the Agent Orange issue. There is limited but suggestive evidence of an association with diabetes (10% of the population has DM and very very few of them were ever exposed to AO) and no proposed evidence linking UCTD to paternal dioxin exposure. http://www.nap.edu/catalog.php?record_id=18395 ...Read more

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What are the half-lives of Isosorbide MN and Nifedipine?

What are the half-lives of Isosorbide MN and Nifedipine?

Approximately: 5 hours for Isosorbide Mononitrate used for prevention of angina pectoris due to coronary heart disease, HTN and MI. It is a vasodilatory agent that dilates the blood vessels. It lowers blood pressure and reduces the left ventricular preload and after load reducing the hearts oxygen requirement. Nifedipine 1/2 life 2 hours. Calcium channel blocker. Go to Medscape or Drugbank for more info. ...Read more

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Please describe the medication: nifedipine?

Please describe the medication: nifedipine?

Calcium channel bloc: Nifedipine is a common calcium channel blocker that is used commonly as an antihypertensvie. It has many uses in cardiology and is even used in pregnancy as a tocolytic (to reduce preterm contractions). It has many forms. ...Read more

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How long does it take for nifedipine to work?

How long does it take for nifedipine to work?

Depends: It comes as a long acting form and a short acting form. If you take a short acting capsule on an empty stomach, it will work within 1-2 hours. If you cut off the end and squeeze the medicine under your tongue (not recommended), it will work in 1-2 minutes but can cause excessive fall in BP so can be dangerous. ...Read more

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How long does it take to achieve effective nifedipine level?

4-5 doses: Usually it takes about 4-5 doses to achieve a steady state of most drugs. Full effects on blood pressure for instance may take up to 4 weeks to be seen. ...Read more

Dr. Quang Nguyen
2,020 doctors shared insights

Diabetes Type 2 (Definition)

Diabetes Mellitus type 2, or adult onset diabetes, is a condition that is caused by insulin resistance. This means that the muscle and fat cells of the body do not take up blood glucose, leaving a high blood glucose. Some type 2 ...Read more


Dr. Allen Fischer
276 doctors shared insights

Nifedipine (Definition)

Nifedipine is a common calcium channel blocker that is used commonly as an antihypertensvie. It has many uses in cardiology and is even used in pregnancy as a tocolytic (to reduce preterm contractions). ...Read more