Doctor insights on:
Niacin Vs Niacinamide For Benefits
Lipid effect, flush: Niacin is a b vitamin that is often used to treat lipid (cholesterol and triglyceride) disorders. Nicotinamide is another vitamin in the vitamin b group. Although Niacin and nicotinamide are identical in their vitamin activity, nicotinamide has no significant cholesterol or triglyceride effects. Also, nicotinamide does not cause skin flushihg that can be a limitation to use of niacin. ...Read more
Good question.: The niacinamide form of Niacin is a b vitamin (it's in your cereal) which does not lower cholesterol like the nicotinic acid form of niacin. Since nicotinic acid causes flushing, makers have tried changing the formulation so it's "flush-free" but will still lower cholesterol. The active ingredient of your cholesterol-lowering Niacin preparation should always be nicotinic acid. ...Read more
Niacin is best: No-flush Niacin can either refer to a slow release preparation or inositol. Slow release preparations are better tolerated than immediate release products, but the lipid lowering effects are somewhat less potent than immediate or extended release niacin. For comparable efficacy a higher dose of slow release is usually needed. Inositol and niacinamide not improve lipids and should be avoided. ...Read more
Could you please tell if and how NIACIN (or NIACINAMIDE) deficiency play any role in synthesis of TETRAHYDROBIOPTERIN? Thank you.
Niacin deficiency would be expected to reduce synthesis as Niacin is needed to produce NADP and NADP is a co-factor in converting Dihydrobiopterin into Tetrahydrobiopterin, which is needed to synthesize serotonin, dopamine, melatonin, epinephrine, norepinephrine and nitric oxide and to metabolize phenylalanine.
Fortunately supplemental niacin and niacineamide are affordable and readily available. ...Read more
Essential Vitamin: Vitamin b3, also known as Niacin or nicotinic acid, is necessary to maintain health. Niacin is involved in dna repair, production of steroid hormones in the adrenal gland, and is a precursor to nadh and nadph that play vital roles in sustaining cell health. Severe deficiency of Niacin in the diet causes the disease pellagra, which is characterized by diarrhea, dermatitis, and dementia. ...Read more
Depends: Your cholesterol levels will determine how much you need. Your doctor will usually start you out at the lowest dose and work his way up based on tolerance and responnse to therapy. ...Read more
Enduracin versus slo-niacin enduracin is most expensive than slo-niacin does enduracin have clinical benefit? If no I will move to slo-niacin
Niacin: Basically Niacin is Niacin and the differences are arguably not worth a significant monetary outlay. ...Read more
What benefit does niaspan/enduracin have on lpa? Halted aim trial convinced me that niacin to increase HDL has no benefit.
AIM-HIGH: Niacian increases HDL and lowers lpa. The aim-high results can be interpreted in several ways: perhaps Niacin is no good as a preventive agent; perhaps raising levels of high-density lipoprotein cholesterol (hdl-c) is flawed as a preventive strategy; perhaps aim-high had methodologic flaws; or statins are so good that, once you prescribe one, anything else you do will not make much of a difference. ...Read more
PubMed says "no": My search in pubmed (for the docs, mesh searches crossing both "niacin" and "thiamine" with "anxiety") turned up no studies on this whatsoever. Perhaps there is some literature on this outside of the pubmed database (?). If so, I've never heard of it. In general, supra-physiological doses of vitamins are usually either a waste of money or in some cases harmful. ...Read more
Niacin.: Supplementing with 2000-3000mg of flush free Niacin daily can help to control your cholesterol levels quite nicely, even increasing your HDL and converting your LDL to a less harmful subtype. As a negative, Niacin can cause facial flushing and redness so get the flush free variety. And have your liver enzyme values monitored, as they can be affected by Niacin use. NiaSpan (niacin) is prescription Niacin ...Read more
Stick with Rx. Forms: Niacin, a b vitamin, in high doses (1-2) grams a day has a positive impact on the lipid profile. Early studies done with Niacin in men with heart disease showed no mortality benefit but secondary outcomes reduced recurrent mi. It has been shown to reduce plaque buildup when combined with bile acid binding resins. Recent studies in well treated patients have been neutral, with side effect concerns. ...Read more
Some side effects: All medicines may cause side effects, but many people have no, or minor, side effects. Diarrhea; dizziness; headache; heartburn; increased cough, indigestion, or upset stomach; nausea; temporary skin redness, itching, tingling, or feelings of warmth (flushing); vomiting. ...Read more
A few risks to note: Can cause sugars to go up, flushing, high enough doses can affect the liver (especially when added to a statin), limited data on benefit. In other words the total cholesterol and the LDLs should be the focus of treatment. No mortality reductions with niaspan (niacin) or the fibrate group of drugs. ...Read more
NO: Only time will help clear thc. It can take uo to 1 month for thc to clear. ...Read more