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Doctor insights on: Nexium And Zoloft

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Dr. Heidi Fowler
1,088 doctors shared insights

Sertraline (Definition)

Also called zoloft, (sertraline) is one of selective serotonin reuptake inhibitors, with antidepressant/anti-anxiety actions. May cause headaches, nausea & ...Read more


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I have 3 prescriptions. Zoloft, Nexium (esomeprazole) and clonazepam. Are any of these hard on or dangerous to your liver?

I have 3 prescriptions.  Zoloft, Nexium (esomeprazole) and clonazepam.  Are any of these hard on or dangerous to your liver?

All three of these: Medications are broken down by your liver. If your liver is normal it should not be dangerous. ...Read more

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I've had a very hard time falling asleep for the past few nights. I've only gotten about 3 hours of sleep each night. What are the safest prescription medications that I can use to help me fall asleep? (I take 25mg Zoloft and 20mg Nexium every day).

I've had a very hard time falling asleep for the past few nights. I've only gotten about 3 hours of sleep each night. What are the safest prescription medications that I can use to help me fall asleep? (I take 25mg Zoloft and 20mg Nexium every day).

Find cause: Need more information to know what's causing lack of sleep. Meds should be discussed with prescribing doctor who also should know what's going on that you can only sleep 3 hr/night. Some common reasons: situational stress, mood disorder not fully recognized, excess alcohol or other substance abuse that may be minimized. Keep a log of your sleep pattern and discuss openly with your doctor. ...Read more

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Is 200mg of COq 10 safe and effective for lowering blood pressure? Current meds are Zoloft losartan betapace and nexium (esomeprazole). Any interactions?

Is 200mg of COq 10 safe and effective for lowering blood pressure?  Current meds are Zoloft losartan betapace and nexium (esomeprazole).  Any interactions?

There are two forms: Of CoQ10. Neither has been regulated by the FDA. (One form appears to have more antioxidant properties). Several conditions have been associated with low CoQ10 levels including HTN, heart failure, certain cancers, gingivitis, gastric ulcers, etc. Currently there has not been a consensus arrived at as to the BP lowering effects (due to lack of controlled studies). May affect Zoloft (sertraline) level a bit. ...Read more

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I take my nexium, (esomeprazole) lisinopril, wellbutrin, and sertraline in the morning and atenolol at night are they ok to take like that?

I take my nexium, (esomeprazole) lisinopril, wellbutrin, and sertraline in the morning and atenolol at night are they ok to take like that?

Ok: There's no problem taking them on the schedule you're using. Caution must be exercised when wellbutrin (bupropion) and sertaline are used together as the combination can increase serotonin levels. I'm sure your prescriber monitors you for side effects. ...Read more

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I just found out that im 5 weeks preagnant, few weeks before I took Nexium (esomeprazole) for acid reflux and sertraline for panic attacks. Is that safe for the baby?

Likely OK: Nexium (esomeprazole) not a problem. The jury is not in yet on sertraline during pregnancy. The problems that have been suspected with sertraline appear to be more of a problem later in pregnancy, closer to delivery, with some of these meds being suspected to be involved in some cardiac/breathing problems in newborns at the time of birth with a condition called persistent pulmonary hypertension. ...Read more

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Wellbutrin 150mg, sertraline 50mg, lisinopril 20mg, atenolol 25mg and Nexium (esomeprazole) 40 mg my internal med doc said there all helping are these high doses?

Wellbutrin 150mg, sertraline 50mg, lisinopril 20mg, atenolol 25mg and Nexium (esomeprazole) 40 mg my internal med doc said there all helping are these high doses?

Not high: Max dose of Wellbutrin: 450 mg a day; Sertraline: 200 mg a day; lisinopril: 80 mg a day; Atenolol: 100 mg a day. Unless you weigh 80 pounds, these are not large doses. ...Read more

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My son can't swallow a Zoloft (sertraline) be crushed?

My son can't swallow a Zoloft (sertraline) be crushed?

Tablet yes cap no: There are two forms of Zoloft (sertraline). The capsule form cannot be crushed but the tablet form can. Your pharmacist may be able to make a liquid form for your son if the capsule is your only option.

Be sure to follow the directions of his doctor for dosing adjustments and be sure to keep all appointments for follow up while he is being treated with this medication. ...Read more

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Can't Zoloft (sertraline) make u sweat very badly even at night and resemble lymphoma sweats?

Can't Zoloft (sertraline) make u sweat very badly even at night and resemble lymphoma sweats?

Zoloft (sertraline) sweats: The whole class of ssri medications (including prozac, zoloft, paxil, (paroxetine) etc.) can cause night sweats, particularly as you are stopping or reducing the medication. Paxil (paroxetine) is the worst offender in this group. Some patients have this symptom even while taking the medication. Usually it will go away after a few weeks. ...Read more

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When I haven't taken my Zoloft (sertraline) in 2 + days (rarely happens that I skip) why does it cause me headaches?

When I haven't taken my Zoloft (sertraline) in 2 + days (rarely happens that I skip) why does it cause me headaches?

Withdrawal symptom: When you miss your zoloft (sertraline) dose, you could be experiencing some withdrawal (or what the drug companies call "discontinuation") effects -- which can include headache. I'm glad you rarely skip your doses for 2+ days. ...Read more

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Why can't I take oxyelite pro while I'm taking zoloft (sertraline)? I'm in medical field so complicated answer is okay

Why can't I take oxyelite pro while I'm taking zoloft (sertraline)? I'm in medical field so complicated answer is okay

Unregulated: All supplements are unregulated by fda, so they can put 'pro' and 'awesome' and whatever you want to hear to get excited and spend money, but the fact is there are things they can put that do work, and are dangerous. I see kidney stones, heart, liver and other problems that come from muscle and energy supplements. So with or without zoloft, (sertraline) I wouldn't recommend that stuff. ...Read more

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I haven't taken my medication (Zoloft 200mg and Lamictal 200mg) for 2 weeks. Should I take my full dose again or half?

I haven't taken my medication (Zoloft 200mg and Lamictal 200mg) for 2 weeks. Should I take my full dose again or half?

Do you need them?: These are antidepressants. If you function well without using them, then stay off of taking them completely. Otherwise, you can go back on them(if you remain depressed without using them.)
These doses if tolerated before are fine to take them like before. ...Read more

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Can't remember for the life of me if I took my Zoloft (sertraline) this morning. I'm on 100 mg. Should I risk double dosing or skip it?

Can't remember for the life of me if I took my Zoloft (sertraline) this morning. I'm on 100 mg. Should I risk double dosing or skip it?

Can count pills: On the bottle it should list the day it was filled and the rate at which you are supposed to take it (once or twice a day). You can then count the number of pills left and decide whether you have taken the right number of pills. Also, one extra or fewer dose of Zoloft (sertraline) is not going to throw you into a toxic state. ...Read more

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I asked a question before about which could medications I could take with zoloft (sertraline). I didn't get an answer, and I can't sleep due to this cough.

I asked a question before about which could medications I could take with zoloft (sertraline). I didn't get an answer, and I can't sleep due to this cough.

Some remedies: A mixture of chamomile tea with honey & a small amount of lemon juice may help. Pour boiling water over thinly sliced organic ginger. Steep for at least five minutes in a covered pot. Add 2 to 3 tbs of honey & sip. Hydrate well with broth or water. These are just a few options. Take care. ...Read more

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I've been on Zoloft (sertraline) 4 4 years now done good but the last few mo im sacttered braind can't fouse or remenber things could this be a side effect?

I've been on Zoloft (sertraline) 4 4 years now done good but the last few mo im sacttered braind can't fouse or remenber things could this be a side effect?

Scattered: Yes. Long term treatment with a serotonin boosting drug like sertraline (zoloft) can, in some patients cause a frontal lobe type symptom complex where focus, attention and thinking is altered. Talk with your doc about this. Good luck! ...Read more

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I didn't take my night dose of Zoloft (sertraline) & strattera! What can happen? I already didn't see benefit on meds. Will this missed dose affect its effectivity?

I didn't take my night dose of Zoloft (sertraline) & strattera! What can happen? I already didn't see benefit on meds. Will this missed dose affect its effectivity?

Not a Problem: Skipping a day in taking these medications will not be a problem. Just take your next scheduled dose. The effectiveness for both drugs will depend on amount of drug and the time it is in the system. Both depend on time to know if they will be effective. Give 4 weeks for both, then ask your doctor if should increase the doses. ...Read more

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I'm on Zoloft (sertraline) 50mg BD, Clomfranil 25mg OD. I can't get rid of a thought about an argument made with someone? Its really painful. Any advice please

I'm on Zoloft (sertraline) 50mg BD, Clomfranil 25mg OD.
I can't get rid of a thought about an argument made with someone? Its really painful. Any advice please

More OCD treatment: It looks like you're being treated for depression and OCD. It also sounds like the treatment for the OCD is NOT working well- suggest you get in to see and talk to a psychologist and psychiatrist to sort things out. Go easy on yourself, and trust it will get better with time and regular medication ...Read more

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I've been on Zoloft (sertraline) for a few yrs. I have noticed weight gain. I want to switch to something that won't make me gain, what works best for my age? 17.

I've been on Zoloft (sertraline) for a few yrs. I have noticed weight gain. I want to switch to something that won't make me gain, what works best for my age? 17.

Talk w/psychiatrist: This is something you need to discuss with your own psychiatrist, preferably an adolescent psychiatrist. Some medications have additional risks in young people, and you want to be safe and well. Lexapro (escitalopram) is a reasonable choice in adults, but reviewing your concerns with your own doctor would be better than asking doctors who don't know you (like us on healthtap). Good luck! ...Read more

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What if im ok on 100mg Zoloft (sertraline) but don't feel effects of 1mg klonopin 2x a day should I ask to increase klonopin to 2mg 2x a day? I can't find a balance

Zoloft (sertraline) Klonopin : It would help to know what anxiety disorder you have and how you expect to feel on klonopin. That aside, a study was just completed that showed that a significant number of patients with social anxiety did well on zoloft (sertraline) and 3 mg per day of Klonopin along with psychotherapy. Am j psychiatry 2014 jan 1; 171:44. Best wishes. ...Read more

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What would happen if I have been taking 200mg of Zoloft (sertraline) and my body doesn't need it just wondering if I would have serotonin symdrome and what symptoms?

What would happen if I have been taking 200mg of Zoloft (sertraline) and my body doesn't need it just wondering if I would have serotonin symdrome and what symptoms?

Unprescribed?: If you've been taking zoloft (sertraline) & your body doesn't need it, you'd be exposed to potential side effects like GI upset, nausea, diarrhea, etc -- but none of the benefits. Side effects can happen even if your body does need zoloft (sertraline). If on 200mg zoloft (sertraline) and no other conflicting medications or drugs, serotonin syndrome is very unlikely. If taking unprescribed medications, this is another issue. ...Read more

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I've been on Zoloft (sertraline) 150mg for years now and my anxiety is under control but the last few days I can't sleep and im not anxious i done get it, what coul?

I've been on Zoloft (sertraline) 150mg for years now and my anxiety is under control but the last few days I can't sleep and im not anxious i done get it, what coul?

Anxiety ; insomnia: Have you added any new medicines, supplements, or recreational drugs -- or stopped any of the same? Do you drink alcohol? Any changes to your pre-sleep routine? Anything worrisome on your mind? How is your mood, and your energy? These are some things I'd ask in working with you -- your own psychiatrist will want to know the same. Cognitive behavioral therapy can help w/insomnia as well. ...Read more

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Can you explain how this combination works? I take 25mg Zoloft (sertraline) 1 MG Ativan at night. I had 3 drinks and blacked out with no memory for about 7 hours. I won't be doing this again but I am very curious as to the combination. I am planning on c

Can you explain how this combination works? I take 25mg Zoloft (sertraline) 1 MG Ativan at night. I had 3 drinks and blacked out with no memory for about 7 hours. I won't be doing this again but I am very curious as to the combination. I am planning on c

Not advisable: Ativan will commonly cause amnesia. You should not drink in combination with the Ativan, the result can be as you found, but can be more serious including death. Your dose of Zoloft (sertraline) is very low, and not likely an interaction with either the alcohol or ativan. ...Read more

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On Zoloft (sertraline) and feeling worse, can't think/focus. What do you suggest?

Zoloft (sertraline) side effect: Call your prescriber right away, explaining how you feel. There are many alternatives that can offer the effect you need. ...Read more

Dr. Heidi Fowler
1,043 doctors shared insights

Zoloft (Definition)

Zoloft is a serotonin reuptake blocker which is a kind of ...Read more