Doctor insights on:
Nexavar Side Effects
Nexavar (sorafenib): Nexavar (sorafenib) is a targeted therapy that can block the ability of tumor to recruit blood vessels and stop the tumor from growing. This can be used in conjunction with locoregional therapy (chemoembolization) in certain situations or on its own. ...Read moreSee 1 more doctor answer
What to expect at the last few days of life for my mom, 84, stage 4 hepatoma, on nexavar, (sorafenib) but she is refusing to use the med. What to expect?
Yes, for Stage 4: Nexavar, or sorafenib, is used to treat advanced, unresectable hepatocellular carcinoma. It is also used to treat patients with advanced kidney cancer. This drug is a multikinase inhibitor and works by decreasing tumor growth and replication, by inhibiting the formation of blood vessels that tumors rely on to get nourishment. This is not a curative treatment, prolonging survival on average 7 mo. ...Read more
My husband has been diagnosed with hepatocellular carcinoma and he is taking nexavar; I would like to know if you have experience with this drug resu?
Yes: Nexavar, also called sorafenib, is an oral drug that was approved in 2007 for treating hepatocellular carcinoma that cannot be surgically removed. It delays the growth of the tumor, but it does not cure it. Diarrhea, hair loss, and hand/foot syndrome (redness and peeling of hands and feet) are the main side effects. Good luck to you both! ...Read moreSee 2 more doctor answers
My father 62 year is being treated with stage4 hcc. Tace is done 3 week s ago. He has been put on nexavar (sorafenib). How much time left for him. Please help?
It varies: Hcc is a serious disease with a variable survival depending on his liver functions( child pugh score). Average surviival is 6-12 months, with occasional surviors living up to two years. ...Read more
Hi dear doctor
my son 21 yo is inoperabl stage 4a sınce dıagnosed october 2013 with pvt. he use sorafenib and he had yıtrıum embolization in march 2014.the tumor diagnosed withaout any symptom or marcer by me at usg.the tumor minimized 2 CM and now sin
Sounds complicated: With a question like this you are best suited trying to find an oncologist on HealthTap that has a "Concierge" practice. You may then inquire to join his/her practice and consult them directly in regards to your question(s). Otherwise, this is too complicated to be answered in this 400 character or less format. Remember if you seek a formal online consultation, have all available info ready. ...Read more
Does advanced liver cancer mean anything but death? Is there any chance to survive? My father has been taking nexavar (sorafenib) for 2 months...
If the cancer is: A single lesion, it can sometimes be completely resected( cut out), and one can be cured. ...Read more
Used for Stage 4: Nexavar, or sorafenib, is used to treat advanced, unresectable hepatocellular carcinoma. It is also used to treat patients with advanced kidney cancer. This drug is a multikinase inhibitor and works by decreasing tumor growth and replication, by inhibiting the formation of blood vessels that tumors rely on to get nourishment. This is not a curative treatment, prolonging survival on average 7 mo. ...Read more
My mom, 84, if she stop her nexavar (sorafenib) for her primary liver cancer, what would her life expectancy be?
8 months: Without more details it's hard to know. Best supportive care would be 8 months. Why has she not had liver directed therapy? An elevated AFP is not a contraindication to treatment. I recently treated an 84 yo otherwise healthy woman with hcc with an AFP of 3500. The tumors are now gone and her AFP is 2! if your mom is healthy and you wish more aggressive treatment, it can be done. ...Read moreSee 1 more doctor answer