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Doctor insights on: Neurofibromatosis 1 Nf1

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Dr. Hunter Handsfield
123 doctors shared insights

Hsv Type 1 And 2 (Definition)

A variety of infections caused by herpes simplex virus types 1 and 2. Type 1 infections are marked by the eruption of vesicles on lips or at the external nares; type 2 by such lesions on the genitalia. Both types often are dormant and reappear during febrile illnesses or even physiologic states such as menstruation. The viruses become latent and and may not ...Read more


Dr. Liawaty Ho Dr. Ho
1 doctor agreed:
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CML 10/12. Gleevec .5 log at 6 mths. Sprycel (dasatinib) .5 log at 6 mths. Stem cell transplant 4/14. 7/14 Blast crisis - 65% blast BM + Aspergillus F lung Help?

Dr. Liawaty Ho Dr. Ho
1 doctor agreed:
CML 10/12. Gleevec .5 log at 6 mths. Sprycel (dasatinib) .5 log at 6 mths. Stem cell transplant 4/14.  7/14 Blast crisis - 65% blast BM + Aspergillus F lung Help?

Difficult case: it is a complicated case obviously. first and foremost the infection has to be treated. i would suggest you to follow up with ID and oncologist very closely. importantly is to check if there is certain mutation like T315i mutation as this mutation is resistant to gleevec, sprycel, tasigna (nilotinib) - and should be treated with ponatinib or aurora kinase inhibitor etc. discuss with oncologist. God bless ...Read more

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Is SIRT worth doing for liver liver metastases 1x 7 cm 1x 6 cm 8 under 2 cm?

Is SIRT worth doing for liver liver metastases 

1x 7 cm
1x 6 cm
8 under 2 cm?

Yes: Multiple liver lesions can be treated by a number of approaches because what is in liver will not spread. Originally ligation of hepatic artery was used since portal vein supplies hepatocytes and hepatic artery the metastatic tumors.Can be used with SIRT which is a form of RT treatment wherein a dose of SIR-Spheres® microspheres are delivered up to 40 times higher than conventional doses. ...Read more

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Age 39 Smoker Male, Blood Sugar Normal; TIA Stroke 1 week back.Taking Ecosprin AV75. MRI Brain: Tiny ischemic foci on both froantal lobe. Any risk?

Age 39 Smoker Male, Blood Sugar Normal; TIA Stroke 1 week back.Taking Ecosprin AV75. MRI Brain: Tiny ischemic foci on both froantal lobe. Any risk?

Yes..serious stroke: Your info suggests brain vascular problems that are causing ischemia (reduced blood flow to brain tissue) which until now has been mild or transient but unless you quit smoking , among other preventive measures, you risk more serious ischemic brain injury or stroke ...Read more

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Till what age does wrist circumference increase? 20, wrist size 6.7 inches,height 173 cm, ankle 8.9 inches.

Till what age does wrist circumference increase? 20, wrist size 6.7 inches,height 173 cm, ankle 8.9 inches.

Varies somewhat: The mechanism by which the circumference of the wrist increases includes the growth of the bones that make up the wrist, the joint spaces in the wrist, and also the soft tissues of the wrist as well. Bone growth in males can vary quite a bit anywhere usually between 14 and 21. Muscle and tendon size vary with use. Even elderly patients can have increase in wrist circumference due to arthritis. ...Read more

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2001 Hysterctomy. 5.5x3.8x4.8cm mildly complex cyst w/in rt. ovary, total size of ovary 6.0,single thick avascular curvinlear septation.3.3 simple cyst on lft, Age 49. Calcium,ser-10.3; Fsh,133.6

2001 Hysterctomy.  5.5x3.8x4.8cm mildly complex cyst w/in rt. ovary, total size of ovary 6.0,single thick avascular curvinlear septation.3.3 simple cyst on lft, Age 49.  Calcium,ser-10.3; Fsh,133.6

Talk to your doctor: The size of your right ovary is about twice the size of a normal ovary and likely most of that is taken up by the cyst. The presence of a thick septation suggests the possibility of more than just a simple cyst but does not confirm anything. Your labs don't really confirm anything and you may need more imaging. Your doc may want a Ca125 test. You need to have a frank conversation with him/her. ...Read more

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Anyone heard of incontinentia pigmenti a rare genetic condition?

Anyone heard of incontinentia pigmenti a rare genetic condition?

Rare X linked pbm: Ip is a rare multisystem affliction that is seen in girl infants & fatal to males in the womb. Incidence estimates run 1/40000-1-50000 births. It appears sometimes as a blistering rash, warty or just increased pigmentation in a swirling or streaking pattern. For a more see: www.Ncbi.Nlm.Nih.Gov/pmc/articles/ pmc2729954/?Tool=pmcentrez. ...Read more

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What can be done for a 6.1 cm liver metastases ? Plus other 3 spots under 1 cm

What can be done for a 6.1 cm liver metastases ? Plus other 3 spots under 1 cm

Resect if possible: Liver metastases are an unfortunate consequence of some cancers. Sometimes they are can be removed with surgery if the patient can tolerate it. Many times surgery is not possible, so patients need to take chemotherapy. Chemotherapy would be chosen depending on the original cancer. Combinations of surgical removal and chemotherapy have led to long prognosis in colorectal cancer, for example. ...Read more

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What is: "r/o atypical Nevus" in doctor's note?

What is: "r/o atypical Nevus" in doctor's note?

Biopsy: An atypical Nevus is suspicious for malignancy. Therefore a biopsy is often done to establish a histopathological diagnosis and treatment plan. ...Read more

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Can a patient stage 1 papillary thyroid cancer with BRAF mutation positive live more than 20 years ( she is 51 years old) ? Thank you very much!

Can a patient stage 1 papillary thyroid cancer with BRAF mutation positive live more than 20 years ( she is 51 years old) ? Thank you very much!

Yes: Papillary thyroid cancer is very common and some people do not even know they have it as small tumors may be found on autopsy when they die of something else. Generally tumors are graded by how ugly they look to the pathologist and how far they've spread. Your tumor has also been molecularly characterized. There are new treatment options available. Please discuss with your oncologist. ...Read more

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What risk assessments tests to do with smoldering multiple myloma pls tel me is it smoldering myloma when m spike is below 1 but 14 percent plasma cel?

What risk assessments tests to do with smoldering multiple myloma pls tel me is it smoldering myloma when m spike is below 1 but 14 percent plasma cel?

Regular follow-up: Smoldering myeloma is a pre-malignant condition with about 10% people developing myeloma/year. You correctly defined your condition as smoldering myeloma. There is need to do repeated blood tests every 6-12 months. Please follow you doctor's advice. ...Read more

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How do 1 gain weight within 1 month?

How do 1 gain weight within 1 month?

See Dr., then eat...: If one is truly underweight (based on height, family background, and body type), a Dr. can evaluate for a hormonal, digestive, or other disorder. If no medical cause is found, then one can add weight by eating more calories of nutritious foods, while also doing weight-training to increase muscle. Proteins: egg white, chicken breast, salmon,... Better fats: olive oil, peanuts, almonds, tofu,... ...Read more

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I'm 22, female, type 1 diabetic 20 years & graves disease. Had baby 12/2 & sick for month. Angina, irregular heartrate, syncope, short of breath. Help?

I'm 22, female, type 1 diabetic 20 years & graves disease. Had baby 12/2 & sick for month. Angina, irregular heartrate, syncope, short of breath. Help?

PCP visit: I would suggest having your thyroid function tests obtained, and an evaluation for autoimmune disease. The other test that you should have while you are at the PCP, is an EKG. ...Read more

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Blue veins on pelvis sign of ovarian cancer?

Blue veins on pelvis sign of ovarian cancer?

Usually not.: Although a pelvic or abdominal tumor can lead to an increase in pelvic veins seen on the skin, there are more frequent causes such as malfunctioning (refluxing) valves in the saphenous system or even in the ovarian veins (pelvic congestion syndrome).A ct of the abdomen and pelvis as well as a leg venous ultrasound will help to make the diagnosis. See a vein specialist. ...Read more

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My mom has amyotrophic lateral sclerosis. (lou gehrigs). What is this exactly?

My mom has amyotrophic lateral sclerosis. (lou gehrigs). What is this exactly?

Bad disease: ALS damages the motor nerve cell in brain and spinal cord causing progressive arm and leg weakness, muscle flickering, with progressive disability. If the disease affects the lower part of the brain, problems with tongue atrophy, swallowing, and breathing can create major crises, and even need for tracheostomy. The sole available drug, Riluzole does delay trach, but no effect on strength. ...Read more

Dr. Gerald Mandell
171 doctors shared insights

Neurofibromatosis (Definition)

A condition that causes tumors to form in the brain, ...Read more