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Doctor insights on: Neuroblastoma

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Dr. Troy Reyna
554 doctors shared insights

Neuroblastoma (Overview)

A type of cancer that forms in certain types of nerve tissue. It most frequently starts from one of the adrenal glands.


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What are the tests for neuroblastoma?

What are the tests for neuroblastoma?

Urine VMA/HVA: In about 90 % of children with neuroblastoma, the chemicals called vma and/or hva in urine are increased. Thus this can be used as a screening if one suspects neuroblastoma. But it does not detect 100 % of patients, thus normal urine vma/hva does not exclude the diagnosis of neuroblastoma. This is particularly true in newborn infants with neurobllastoma or children with neuroblastoma in the chest. ...Read more

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Dr. Troy Reyna
554 doctors shared insights

Neuroblastoma (Overview)

A type of cancer that forms in certain types of nerve tissue. It most frequently starts from one of the adrenal glands.


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How does neuroblastoma show up?

How does neuroblastoma show up?

Early: Neuroblastoma usually shows up in childhood. Usually under two years of age. It is a cancer of the sympathetic nervous system. It can appear anywhere from head and neck to pelvis. There are four stages plus a special 4s. The higher the stage the more extensive and virulent the tumor. It is treated with combination surgery, chemotherapy and sometimes radiation. ...Read more

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Is nausea a symptom of neuroblastoma? What are other symptoms?

Is nausea a symptom of neuroblastoma? What are other symptoms?

It can be-see below.: Symptoms of neuroblastoma can vary (depending on where it's growing, where it spreads to, and metabolically active by-products), but can include abdominal fullness or distension, nausea/vomiting, abdominal pain, fatigue, bone pain, change in bowel or bladder habits, fevers, weight loss, decreased appetite, general malaise, irritability, fractures, high blood pressure, eyelid bruising, and others. ...Read more

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What are the symptoms of neuroblastoma?

What are the symptoms of neuroblastoma?

Mass, pain: Neuroblastoma is a solid cancer of infants and children. It presents with a swelling in the abdomen, pain, weakness, pallor. If it occurs in the chest it may be silent until a chest xray is done for some other purpose and found by accident or if big enough can cause resiratory symptoms. ...Read more

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Looked it up and all of these are signs of neuroblastoma.But how old is too old to be diagnosed with that?

Looked it up and all of these are signs of neuroblastoma.But how old is too old to be diagnosed with that?

Adults get disease: While the vast majority of patients who are diagnosed with neuroblastoma are young (<10 years old), adults (defined as those >20 years old) can get the disease. Thus, it is never too old to be diagnosed with neuroblastoma. Getting a 2nd opinion for a new adult diagnosis of neuroblastoma would be a quite reasonable thing to do, given how rare it is. ...Read more

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In the diagnosis for neuroblastoma, why should a tissue sample be taken?

In the diagnosis for neuroblastoma, why should a tissue sample be taken?

Staging: Beyond confirming the diagnosis, tissue is needed for neuroblastoma staging which then determines the therapy that will be recommended. You need to know if the tumor has "favorable" or " not favorable" appearance under the microscope as well as if certain genetic changes are present in the tumor tissue (myc amplification and others) to fully stage the tumor and recommend appropriate therapy. ...Read more

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Do you have to have a biopsy to diagnose neuroblastoma?

Do you have to have a biopsy to diagnose neuroblastoma?

Usually: The diagnosis is usually suspected by age of patient, symptoms and imaging results. However it is generally confirmed by a pathologist who looks at the biopsied tissues under a microscope. Neuroblastoma tumors have a specific look under the microscope and are often described as small, blue and round cells. ...Read more

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Does anyone know if there is a link between neuroblastoma and infant seizures my son was recently diagnosed with both?

Does anyone know if there is a link between neuroblastoma and infant seizures my son was recently diagnosed with both?

Can be associated: Neuroblastoma may indirectly cause seizures by causing high blood pressure, which then results in hypertensive encephalopathy- which can cause seizures, however this is pretty rare. Most often neuroblastoma presents first with vague symptoms like tiredness, fever and decreased appetite. Neuroblastoma is also the only known tumor that may spontaneously regress in specific infant cases. ...Read more

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Could neuroblastoma cause pain?

Different forms of : Pain are possible. Mayo clinic is an excellent resource: http://www.Mayoclinic.Org/diseases-conditions/neuroblastoma/basics/symptoms/con-20027487. ...Read more

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What does occult neuroblastoma mean?

Neuroblastoma: I have not heard of the term "occult" neuroblastoma - a patient either has a neuroblastoma or does not, the use of the term "occult" is not typically used here. ...Read more

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How do you treat children with neuroblastoma?

How do you treat children with neuroblastoma?

Depends on the stage: Low stage disease, which occurs mainly in very young infants, at times needs surgical resection followed by observation (no chemo). More advanced stages or neuroblastoma occuring in older children usually requires surgery and chemo. Very high risk disease (based on many factors) requires chemo, high dose chemo, stem cell infusion, radiation and more chemo. Good luck. ...Read more

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Is there any really effective treatment of neuroblastoma in children?

Is there any really effective treatment of neuroblastoma in children?

Yes: Thankfully treatment of neuroblastoma has improved dramatically over the last decade. That is not to say that all children are curable; the outcome is greatly dependent on the risk stratification that your oncologist perform to tailor treatment. As expected children in the high risk group do not do as well as those in the low risk group. ...Read more

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How can we cure neuroblastoma?

How can we cure neuroblastoma?

Support new research: Depending on the risk group, we cure the majority of children with neuroblastoma using a combination of surgery, chemotherapy, radiation and stem cell transplant. However, there are a significant number of children with high-risk neuroblastoma that ultimately succumb to their disease. Immunotherapy, alk inhibitors, mibg therapy and others are being tested now. More targeted therapy is needed... ...Read more

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What is neuroblastoma?

What is neuroblastoma?

Cancer: Neuroblastoma is a cancer of the nerve cells in the adrenal gland, neck, chest or spinal cord. It is usually found in young children under the age of 5, most under 2. The outcome of treatment is determined by the age of the child, stage of the tumor, location, spread and histology. ...Read more

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What is a neuroblastoma?

Cancer: Neuroblastoma is a cancer of the nervous system. It usually occurrs in children ages 1-5. The younger the child the better the prognosis. There are four stages of the disease from mild to severe and this affects prognosis also. Ttreatment requires surgery and/or chemotherapy. ...Read more

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How common is neuroblastoma?

Relatively common: Childhood cancer is rare. That being said, neuroblastoma makes up 8-10% of childhood cancer, and is the most common cancer in infants. About 700 children are diagnosed with neuroblastoma in the us each year. ...Read more

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What is occult neuroblastoma?

What is occult neuroblastoma?

Difficult to say: Neuroblastoma is a pathological diagnosis depending upon a certain tissue type. It may be referring to a variant of neuroblastoma, since neuroblastoma is well known to evolve into more mature or less malignant tissue types like ganglioneuroma. Etc. ...Read more

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