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Doctor insights on: Neuro Endocrine Features In Small Cell Lung Cancer

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Dr. Michael Gabor Dr. Gabor
Diagnostic Radiology
29 years in practice
University of Connecticut School of Medicine
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How common is a false negative ct when scanning for small cell lung cancer. Weight loss and fatigue present with some endocrine issues.

How common is a false negative ct when scanning for small cell lung cancer.  Weight loss and fatigue present with some endocrine issues.

Very uncommon.: In some respects it depends on how the scan was performed, but, for example, with low dose screening chest CTs, reported sensitivities are generally well above 90%, and in some studies, approach 100% ...Read more

Dr. Barry Rosen
4,316 doctors shared insights

Cancer (Definition)

Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more


Dr. Amy Deeken Dr. Deeken
Pathology
16 years in practice
Northeastern Ohio Universities College of Medicine
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How do you cure small cell lung cancer?

How do you cure small cell lung cancer?

Rarely is cured.: It depends on the stage and if the cancer has spread. Small cell lung carcinoma is usually treated with chemotherapy and radiation. It is one of the most aggressive subtypes of lung cancer. Definitely consult with an oncologist, but patients with small cell should weigh the benefits of participating in treatment offered in clinical trials at university centers. ...Read more

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Dr. Peter Sadow Dr. Sadow
Pathology
13 years in practice
University of Chicago Pritzker School of Medicine
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What can be done for small cell lung cancer?

What can be done for small cell lung cancer?

Chemotherapy: Small cell lung cancer is a neuroendocrine carcinoma that shows some response to specialized chemotherapy, although this tumor type tends to follow a fairly aggressive clinical course. ...Read more

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Dr. Myron Arlen Dr. Arlen
Surgery - Oncology
60 years in practice
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What is the definition or description of: Small cell lung cancer?

What is the definition or description of: Small cell lung cancer?

Neuroendocrine tumor: Primary lung lesions are comprised mainly of malignant cells of the bronchus or squamous cell cell and malignant cells of lung glandular tissue or adenocarcinoma of lung. The 3 rd tumor is neuroendocrine or small cell Ca. It is similar in structure and response to the carcinoid of bowel.Tumors other than mets are therefore classed as small cell and non small cell tumors. ...Read more

Dr. Richard Michaelson Dr. Michaelson
Pathology
36 years in practice
Medical University of South Carolina College of Medicine
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There's small cell lung cancer, but are the small cell other cancers?

There's small cell lung cancer, but are the small cell other cancers?

Yes: Small cell carcinomas may arise in many organs. They typically show evidence of differentiation toward certain glandular structures, called 'neuroendocrine' differentiation. Small cell cancers tend to be rapidly proliferating tumors, and thus may be treated initially with chemotherapy. ...Read more

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Dr. Liawaty Ho Dr. Ho
Internal Medicine - Hematology & Oncology
19 years in practice
Udayana University Faculty of Medicine
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What are the tests for non-small cell lung cancer?

What are the tests for non-small cell lung cancer?

Nsclc: First of all, a biopsy will need to be done to the lung mass/nodule not only to establish diagnosis but also to find the histology and genetic profile of the cancer. Then, complete staging work-up with pet/ ct scan need to be done to stage the cancer. The treatment will depend on the histology/molecular-genetic mutation status, stage, as well as overall condition and preference of a patient. ...Read more

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Dr. Scott Moon Dr. Moon
Radiation Oncology
26 years in practice
University of Hawaii John A. Burns School of Medicine
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What's the prognosis for non small cell lung cancer ?

5yr suvival bystage : Ia = 49% ib = 45% iia = 30% iib = 31% iiia = 14% iiib = 5% iv = 1% http://www.Cancer.Org/cancer/lungcancer-non-smallcell/detailedguide/non-small-cell-lung-cancer-survival-rates. ...Read more

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Dr. Gurmukh Singh Dr. Singh
Pathology
45 years in practice
University of Pune, Armed Forces Medical College
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Could you explain what is non small cell lung cancer?

Could you explain what is non small cell lung cancer?

One type of lung: Cancer. It is not easy to explain. There are multiple subtypes within in this type. These are due to smoking and tend to spread locally as compared to early spread through blood for small cell cancer. See this site for more info. http://www.cancer.gov/cancertopics/pdq/treatment/non-small-cell-lung/patient/page1. ...Read more

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Dr. Liawaty Ho Dr. Ho
Internal Medicine - Hematology & Oncology
19 years in practice
Udayana University Faculty of Medicine
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How responsive to?Chemotherapy? Is small cell lung cancer?

How responsive to?Chemotherapy? Is small cell lung cancer?

Very responsive: Small cell lung cancer in general is very responsive to chemotherapy as well as to radiation therapy. However, the problem is that the risk for recurrence is very high. ...Read more

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Dr. Liawaty Ho Dr. Ho
Internal Medicine - Hematology & Oncology
19 years in practice
Udayana University Faculty of Medicine
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What is the survival percentage non small cell lung cancer?

What is the survival percentage non small cell lung cancer?

The stage and others: Will depend on the stage and other prognostic factors. In general, the 5 year overall survival for stage 1 is 60-80%., stage 2 is 40-50%; stage 3 is 10-23%, and stage 4 is less than 10%. These however are the statistics obtained when using regular cytotoxic chemotherapy. With more personalized and more targetted therapy-we are hoping the number will improve. ...Read more

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Dr. Liawaty Ho Dr. Ho
Internal Medicine - Hematology & Oncology
19 years in practice
Udayana University Faculty of Medicine
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What is the treatment for small cell lung cancer?

What is the treatment for small cell lung cancer?

Small cell lung ca: In limited disease, tx would be combination chemo and radiation . In a very limited case, surgery can be done if size is very small, absolutely no spreading to any area/adjacent lymp glands etc. Prophylactic radiation to brain is recommended. In extensive disease, chemo will be the tx.Palliative radiation as needed. For chemo responder, prophylactic radiation to brain can increase survival. D/w md. ...Read more

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Dr. Thomas Birdas Dr. Birdas
Surgery - Thoracic
22 years in practice
National University of Athens Faculty of Medicine
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How is ecog ps2 related to small cell lung cancer?

How is ecog ps2 related to small cell lung cancer?

Not directly: Ecog ps (performance status) refers to the functional status of patients with cancer (any type, not just small cell). Ps 2 describes pts that " are ambulatory and capable of all selfcare but unable to carry out any work activities. Up and about more than 50% of waking hours" ps scores are used to decide how intense of treatment cancer patients should undergo. ...Read more

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Dr. David Cooke Dr. Cooke
Surgery - Thoracic
18 years in practice
Harvard Medical School
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What is surgery like for non small cell lung cancer?

What is surgery like for non small cell lung cancer?

Often cures: Surgery is the standard of care for stage i and ii lung cancer in the physically fit patient, and should be considered as an option in many patients with stage iiia. Often can be done minimally invasively thorascopically or with a robot. Recovery varies with the level of invasiveness. Lung surgery has best outcomes by a board certified thoracic surgeon. ...Read more

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Dr. Richard Zimon Dr. Zimon
Internal Medicine
55 years in practice
Harvard Medical School
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Is muscle loss an early symptom of small cell lung cancer?

Is muscle loss an early symptom of small cell lung cancer?

"Paraneoplastic: syndrome" may include muscle WEAKNESS but muscle loss is RARE ....and only occurs when cancer is advanced and nutritional difficulties occur! Hope this is helpful! Dr Z ...Read more

Dr. Amy Levine Dr. Levine
Radiology
19 years in practice
University of Toledo College of Medicine
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What should I know about nsclc (non small cell lung cancer)?

Smoking: It is frequently caused by smoking. There is too much to discuss in 400 words! try this: http://www.Cancer.Gov/cancertopics/pdq/treatment/non-small-cell-lung/patient/page1. ...Read more

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Dr. Loki Skylizard Dr. Skylizard
Surgery - Thoracic
16 years in practice
University of Michigan Medical School
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What are the surgical options for non-small cell lung cancer?

What are the surgical options for non-small cell lung cancer?

Robot or VATS: Optimal lung cancer surgery, in appropriate candidates, is anatomic lobectomy (part of lung) or pneumonectomy (whole lung). Complete lymph node sample or dissection is integral part of case. Traditional centers use thoracotomy as primary approach. Modern minimally invasive approaches include vats and robotic techniques. Optimal lung cancer treatment is by comprehensive multidisciplinary approach. ...Read more

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Dr. Vamsidhar Velcheti Dr. Velcheti
Internal Medicine - Oncology
4 years in practice
University of Pune, Armed Forces Medical College
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Can you tell me about the best small cell lung cancer treatment nowadays?

See below: Treatment of small cell lung cancer depends on the stage. If it is limited stage the treatments involve chemotherapy along with radiation and if it is extensive stage then chemotherapy is the main stay of treatment (though in some situations palliative radiation can be considered). ...Read more

Dr. Farid Qazi Dr. Qazi
Internal Medicine - Hematology & Oncology
34 years in practice
University of Karachi, Dow Medical College
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How long will someone with non small cell lung cancer with a plural effusion survive?

How long will someone with non small cell lung cancer with a plural effusion survive?

Poor prognosis: If it has not metastasized it is called a wet stage 3 b and in new classification it is stage 4 the prognosis is bad 9 months to a year with modern chemotherapy it is somewhat better but still very limited nber of patients survive beyond a year. ...Read more

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Dr. David Cooke Dr. Cooke
Surgery - Thoracic
18 years in practice
Harvard Medical School
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What are the chances and lifespan of someone who is stricken with non-small cell lung cancer?

What are the chances and lifespan of someone who is stricken with non-small cell lung cancer?

Depends on stage: Lower stage non-small cell lung cancer (nsclc) has better survival based on stage appropriate therapy than later stage tumors. The standard of care therapy for stage i and ii nsclc is surgery. For stage iiia chemoradiation followed by surgery or chemoradiation alone and stage iiib and IV chemotherapy +/- radiation. ...Read more

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Lung (Definition)

Deoxygenated blood enters the lungs from the right side of the heart and travels to the lungs. When you inspire, oxygen flows into the lungs, transverses the capilliares and attaches to hemoglobin down a gradient. At the same time, co2 diffuses into the capilaries and is expelled with exhalation. Oxygen rich blood then flows to the left side of the heart and into the ...Read more


Dr. Tyrone Malloy
251 doctors shared insights

Endocrine System (Definition)

The endocrine system is a group of organs composed of glands that secrete hormones. These hormones have important regulatory functions such as growth, metabolism, ...Read more