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Doctor insights on: Nephrotic Syndrome And Edema

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Is periorbital edema a sign of nephrotic syndrome?

Is periorbital edema a sign of nephrotic syndrome?

It can be: Periorbital edema can be one of the initial symptoms of nephrotic syndrome, but it is always accompanied by edema in other parts of the body (legs, chest, abdomen, etc). The diagnosis is made by checking the amount of proteins that are being excreted in the urine, as well as blood tests that measure the protein (albumin) levels. The exact cause should be evaluated by your doctor. ...Read more

Dr. W. james Chon
3 doctors shared insights

Edema (Definition)

Fluid in the tissues, either caused by something local to the swollen area like an injury or inflammation, or from the body's retention of water. Gravity brings the fluid to the feet & legs in that case. As a general rule, if one foot is swollen, something is wrong with the foot. If both feet are swollen, it's not the feet, but water ...Read more


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Why is there selective proteinuria in nephritic and nonselective proteinuria in nephrotic syndrome?

Why is there selective proteinuria in nephritic and nonselective proteinuria in nephrotic syndrome?

Whoa: Who's your instructor? In nephrotic syndrome, the proteinuria may be selective (mostly albumin, as in most cases of minimal changed disease and any other cause of proteinuria in which the gbm is only modestly damaged) or nonselective (lots of globulin also, as see in the more severe nephrotic syndromes). ...Read more

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Why is there hematuria in nephritic syndrome and not in nephrotic syndrome?

Different physiology: The blood vessels in the glomeruli are damaged by inflammation in the nephritic syndrome sufficient for at least a few of them to bleed. They merely leak protein in the nephrotic syndrome, in which obvious inflammation in the classic sense is not visible but protein-retaining molecules in the gbm are lost. Famously, the membranoproliferative glomerulonephritis family produces both syndromes. ...Read more

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Can people with sjogrens syndrome and severe dry eye syndrome have Lasix (furosemide) eye surgery?

Can people with sjogrens syndrome and severe dry eye syndrome have Lasix (furosemide) eye surgery?

Better not: Lasik surgery tends to make eyes more dry. In the setting of sjogren's syndrome, this could potentially be devastating. Patients who have severe dry eyes can have pain, fluctuating and even poor vision. And this will get worse with age. If you want surgery, you might consider refractive lens exchange, as this will be less drying to the eye and may also get rid of the need for bifocals. ...Read more

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What are the issues with hemolytic uremic syndrome?

What are the issues with hemolytic uremic syndrome?

Concern about kidney: Hemolytic uremic syndrome (hus) is a condition that results from the abnormal premature destruction of red blood cells. Blood cells start to clog the filtering system in the kidneys, which may eventually cause the life-threatening kidney failure seen in hus. Most cases of hus develop in children after colon infection due to e.Coli. Adults can also get hus but often the reason is not due to e.Coli. ...Read more

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What disease would cause nephrotic syndrome?

What disease would cause nephrotic syndrome?

Proper medication: Minimal change (or nil) disease. Correctly diagnosed by biopsy but frequently diagnosed by the symptoms of proteinuria, edema and intact renal function with a bland urine sediment. This responds to steroid therapy most of the time. The presence of blood in the urine, or failure to respond to steroids indicates need for biopsy of kidney with therapy based on those results. Case needs nephrologist. ...Read more

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Is cystic medial necrosis associated with ehlers-danlos syndrome (eds)?

Is cystic medial necrosis associated with ehlers-danlos syndrome (eds)?

Yes: Eds is a disease of the connective tissue with several sub-types. The connective tissue layer of the arteries can be affected and this can lead to cystic medial necrosis. This is a degenerative disease of the media of the aorta and other arteries with loss of elastic tissue and muscle cells. It is a pathological substrate for aortic dissection. Not all people affected get cmn. ...Read more

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Dr. Jay Park Dr. Park
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How serious is nephrotic syndrome?

Dr. Jay Park Dr. Park
3 doctors agreed:
How serious is nephrotic syndrome?

Depends on...: Nephrotic syndrome is a condition resulting from heavy protein loss through urine. A number of different kidney diseases are underlying pathologies. Therefore, the prognosis depends upon the underlying pathology ...Read more

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Can severe pedal edema be associated with smoking?

Can severe pedal edema be associated with smoking?

Ischemia: Smoking causes vasoconstriction of blood vessels and in general is bad for circulation. It can directly or indirectly cause all kinds of circulatory disturbance. Usually, the main concern is ischemia or lack of blood flow though. ...Read more

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Treatment of pitting pedal edema?

Treatment of pitting pedal edema?

Edema: The treatment depends on the cause of the pitting edema. When caused by congestive heart failure it is certainly different from when it is caused by venous insufficiency or hepatic cirrhosis. ...Read more

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Why nephrotic syndrome cause massive proteinuria but no hematuria?

Why nephrotic syndrome cause massive proteinuria but no hematuria?

See below: Nephrotic syndrome can be caused by many diseases . Diseases such as diabetic nephropathy, membranous gn, fsgs may cause nephrotic syndrome hematuria and proteinuria occur in eg lupus nephritis the prescence of only proteinuria helps the clinician narrow down to certain diseases before resorting to a biopsy. ...Read more

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Patient 75 yrs hypertensive diabetic with coarse crepitation and bilateral lower limb oedema ECG RBBB X_RAY cardiomegaly with congestion?

Patient 75 yrs  hypertensive diabetic with coarse crepitation and bilateral lower limb oedema 
ECG RBBB
X_RAY cardiomegaly with congestion?

The question?: Hi, what is the question, it seems the patient has a CHF exacerbation with fluid overload, needs evaluation and treatment at the ER or even hospital setting. Also one needs to find out the cause of exacerbation which is usually is non-compliance with medication and diet. ...Read more

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Are uremia and uremic syndrome the same thing?

Are uremia and uremic syndrome the same thing?

Uremia: uremia is high blood urea. Uremic syndrome is the constellation of symptoms that come from having too much urea in the blood. The higher the urea the more manifestations of the syndrome you will have. Uremic frost is found only when it is very high. ...Read more

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Nephrotic sydrome -kidney can totally recovery?

Nephrotic sydrome -kidney can totally recovery?

Yes: It depends on the cause of the nephrotic syndrome. There are many different causes and further diagnostic evaluation is required to define the cause. Often a treatable cause is found and the syndrome can be reversed. ...Read more

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With acute diffuse proliferative glomerulonephritis caused by systemic lupus erythematosus, why would a patient have uremia and hyperkalemia?

With acute diffuse proliferative glomerulonephritis caused by systemic lupus erythematosus, why would a patient have uremia and hyperkalemia?

SLE DPGN is bad.: The degree of remaining renal function dictates the inability of the kidney to excrete waste products and manage potassium levels. In any severe kidney disease when egfr approaches 15 ml/min uremia and elevated k+ levels are frequently noted. ...Read more

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Can thyroid and poly cystic ovarian syndrome cause ankles to swell?

Can thyroid and poly cystic ovarian syndrome cause ankles to swell?

Possibly: Hypothyroidism can cause swelling and fluid retention. Pcos causes weight gain, but not fluid swelling. However, if your thyroid levels are normal, i would look for a different cause for the swelling. In your age group, the most common causes would be varicose veins, weight related swelling, and/or excess salt intake. ...Read more

Dr. David Schleimer
1,498 doctors shared insights

Swelling (Definition)

Swelling is the enlargement of organs, skin, or other body parts. It is caused by a buildup of fluid in the tissues. The extra fluid can lead to a rapid increase in weight over a short period of time (days to weeks). Swelling can occur all over the body (generalized) or only in one part ...Read more


Dr. Donald Batisky
84 doctors shared insights

Nephrotic Syndrome (Definition)

A condition caused by dysfunction of the kidney, in which large amounts of protein ...Read more