Doctor insights on:
Nephrolithiasis Caused From Multiple Myeloma
I had not heard of "kahler's disease" until seeing multiple questions on healthtap. It is multiple myeloma (mm). "multiple" is from the often seen "multiple" bone lesions (especially in advanced disease). Mm is a cancer of plasma cells [highly specialized b white blood cells (lymphocytes)] that produce antibodies. Sx are crab: hypercalcemia, renal insufficency, anemia, ...Read more
No, usually...: Seeing renal vascular calcification is not uncommon and usually an incidental finding on imaging studies for other causes such as hematuria, kidney infection, stones, etc. . Of course, such patient needs to look into if having similar calcification in other arteries like aorta, since it is merely a part of systemic vascular disease. Besides, kidney function and size have to be watched and.... ...Read more
The myeloma: Family is a proliferation of plasma cells, which produce antibodies or immunoglobulins. Igm is ass.Ociated with waldenstrom macro globulin, igg is the most familiar, but there is also iga, these further produce subunits, kappa and lambda chains. The abnormal clone usually is a xerox machine gone bad producing a copy of one of these chains. Myeloma causes problems by these cells destroying bone. ...Read moreSee 1 more doctor answer
Is increase in plasma cell 15 percent only related to multiple myloma of other malignancies or infection also?
Myeloma or infection: Multiple myeloma is based on all three of the following for diagnosis: 1) 10% or more monoclonal plasma cells; 2) serum or urine monoclonal protein; 3) organ dysfunction (high serum calcium, high serum creatinine, low hemoglobin, or lytic bone lesions/osteoporosis). If 2) is not present, then bone marrow needs 30% plasma cells. Plasma cells can occur with infections. See a doctor for further help ...Read more
Pituitary: No association.Get a more detailed answer ›
Very likely: Get checked for infections e.g. TBGet a more detailed answer ›
No: Granulosa cell tumors of the ovary (and more rarely the testicle in men) are not aquired from sexual activity. These are rare tumors and know specific risk factors are known. However, some studies have shown that the majority if these tumors have a mutation in the flox2 gene. It is not known what causes this mutation to occur or if it is the cause if the tumor. ...Read more
Disseminated peritoneal disease with long segment bowel wall thickening, multiple hepatic and renal nodules - are in favour of neoplastic etiology?
7 YO? Can't post yet: Have to be 17 to post. Seven years old is too young to post, and requires speaking to your pediatrician about your questions until you're old enough to post. Thanks! ...Read more
Location of inflam: Agree with dr. Edmisson. Pbc is autoimmune disease affecting bile ducts; can eventually lead to progressive liver disease and cirrhosis (scarring). Othe types of cirrhosis usually involve inflammation of the liver cells, due to infection (like hep b, c), toxic chemicals, metabolic disease e.g.Nonalcoholic fatty liver (seen in obesity, diabetes) iron overload, damage from alcohol, autoimmune. ...Read moreSee 1 more doctor answer
Unknown: We do not know why some folks get spinal tumors, although some could be secondary to tumor spread from elsewhere, such as lung cancers, maybe associated with smoking. Genetics may play a role. Ms susceptibility can be associated with genetics and environmental influences, but the final cause remains unclear. ...Read more
See a urologist.: The management of multiple kidney stones depends on the size, position, and location of the stones. If they are small & unobstructing, they may be observed. If treatment is necessary, many techniques such as shockwave lithotripsy, ureteroscopy with laser lithotripsy and removal are possible. Large stones may require pcnl or percutaneous removal. See a urologist for assessment and evaluation. ...Read moreSee 1 more doctor answer
Can you have benign microscopic hematuria that isn't caused by bladder cancer, kidney stones, kidney disease etc?
Here are some ...: More than 100 reasons can be listed for microhematuria, i.e., >3 RBCs / HPF, and the odd from urinary malignancy is low at around 3 % in thorough work-up with imaging studies and cystoscopy, etc. Although Doc could not specifically give definite DX for all occasions, a proper attention to ?UTI, ?obstruction, ?stones, ?tumors, and ?kidney inflammation of a wide range of causes should well cover... ...Read more
Treatment for multiple calcified densities at pelvis could represent phleboliths versus distal uretral lithiasis?
Treatment different: Phleboliths are calcified small veins that are not usually clinically important. There usually is no treatment unless associated with hemangiomas, usually in children. Calculus or stone in ureter is referred to ureterolithiasis. This can cause pain and obstruction to the ureter. The stone either passes on its own, or sometimes has instrumentation by urologist. ...Read more
Please explain: renal cortex contains 29 glomeruli, 13 of which
are globally sclerosed. There is focal segmental mesangial
Sclerosis: So Glomeruli are Filteration units of Kidney. Since kidney's main function is Filteration; the health of glome is directly related to renal function. Sclerosis in layman term means scarring. So 13/29 glomes are scarred. Which means approximately 50% of functional units are scarred or non functional. Mesengial hypercellularity refers to the inflammation in the kidney. Very common with FSGS ...Read more
Solutes precipitate and combine to form stones formed of calcium oxalate usually around a nidus of uric acid. Other solutes that form stones are ca and mg phosphates, cystine, and uric acid staghorn calculi form in the presence of chronic urinary tract infections. Stones can be painful, may require ...Read more
- Talk to a doctor live online for free
- Stages of kidney failure from multiple myeloma
- Can black mold cause multiple myeloma?
- Multiple myeloma
- Ask a doctor a question free online
- Multiple myeloma treatment guidelines
- Staging for multiple myeloma
- Multiple myeloma survival statistics
- Multiple myeloma and myelodysplastic syndrome
- Talk to a oncologist online for free