Top
20
Doctor insights on: Neoadjuvant Therapy For Pancreatic Cancer

Share
1

1
Which chemo therapy is most effective for KRAS mutant metastic colon cancer ?

Which chemo therapy is most effective for KRAS mutant metastic colon cancer ?

Same drugs as other: Same chemotherapy drugs are used for treating both types of colon cancer. The only difference is lack of benefit from EGFR inhibitors(Cetuximab and Panitumumab). Avastin (bevacizumab) also works in both types. I trust that you know there are 3 chemo drugs that are widely used(5FU or Capecitabine, Irinotecan and Oxaliplatin) ...Read more

Dr. Barry Rosen
4,368 doctors shared insights

Cancer (Definition)

Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more


2

2
What is radiation therapy treatment for colon cancer?

What is radiation therapy treatment for colon cancer?

Energy beams: For certain types of colorectal cancer, energy beams are focused in the cancerous area. These beams are designed to kill cancer cells and decrease the chance of the tumor growing back. Depending on the situation, radiation can be used either before an operation or after an operation. ...Read more

See 1 more doctor answer
3

3
Hormone therapy for prostate cancer?

Hormone therapy for prostate cancer?

Treatment: Hormone therapy consists of medications that decrease the effects of testosterone on prostate cancer and a man's body. Prostate cancer growth is primarily fueled by testosterone. If testosterone is absent/ineffective, prostate cancer hopefully would stop growing. Hormone therapy has several varieties including pills and injections. Given for advanced disease or at times prior to radiation. ...Read more

See 1 more doctor answer
4

4
What is prognosis With chemotherapy for metastic colon Cancer ?

What is prognosis With chemotherapy for metastic colon
Cancer ?

So many variables: Too many variables to give you a pertinent answer. Consult your oncologist to help you with clinical decisions ...Read more

5

5
How effective is neoadjuvant therapy for treating colon cancer?

How effective is neoadjuvant therapy for treating colon cancer?

Partially: Chemotherapy in all of its forms is only partially helpful in improving the survival of colon cancer. When there is an effective neoadjuvant response the remaining lesion can be successfully resected. complete surgical extirpation is the needed result. As immunochemo becomes more effective then the combination with surgery will even produce better results. ...Read more

6

6
How effective is avastin (bevacizumab) as targeted therapy for the metastatic colorectal cancer?

See below: It is not a curall for colon cancer but is effective therapy to a large extent it depends onthe size and wehre it is. Almost certianly it requires more than this drug to get a cure if acure is possible. ...Read more

7

7
Compare and contrast chemotherapy for aml with chemo for prostate cancer?

Compare and contrast chemotherapy for aml with chemo for prostate cancer?

Different drugs. : Chemotherapy for a hematologic cancer such as AML differs in the drugs & regimens from an epithelial cancer like prostatic carcinoma. AML typically uses Cytarabine and an anthracycline on a specific schedule. In prostate cancer, docetaxel and cabazitaxel are frequently used drugs. Of note, chemotherapy is not as common a treatment for prostate cancer, where hormonal therapy is often used. ...Read more

See 1 more doctor answer
8

8
Is radiation therapy for lung cancer painful?

Is radiation therapy for lung cancer painful?

Possibly: Radiation is painless during the treatments. If the esophagus is in the treatment fields it can cause a painful condition called esophagitis about 3 weeks into the treatment. This is worse when a patient also takes chemotherapy. There are medicines that help this discomfort and when treatment is done it should resolve. ...Read more

See 2 more doctor answers
9

9
Hepatocellular carcinoma.All spleen and partial liver resection.Later,secondary systemic cancer metastasis.any targeted therapy or immunotherapy?

Hepatocellular carcinoma.All spleen and partial liver resection.Later,secondary systemic cancer metastasis.any targeted therapy or immunotherapy?

Yes, for both: Hepatocellular Carcinoma is commonly treated with Sorafenib which is a type of targeted therapy. This is a good choice of treatment in case you have not yet received this drug. Immunotherapy using PD-1 inhibitors has also shown some modest evidence of benefit although it is not yet FDA approved for this indication. Ask your oncologist to guide your treatment further. ...Read more

10

10
Dysphagia and chemotherapy for colon cancer?

Dysphagia and chemotherapy for colon cancer?

It depends ... : Dysphagia is a common side effect with many chemo therapeutic regimens. Some treatments can decrease a patient's ability to fight off fungal and bacterial overgrowth in the mouth and digestive systems. The diagnosis of this isn't usually difficult and can in many cases be treated with medications. ...Read more

See 1 more doctor answer
11

11
Does radiation therapy for lung cancer improve survival rates?

Does radiation therapy for lung cancer improve survival rates?

Yes: It improves survival significantly in stage 1-3 lung cancers. Cyberknife provides survival similar to surgery in stage 1 patients. For stage 2-3 patients, both chemo and radiation may be used to improve survival. In certain patients with stage 4 cancer (such as with spread to the brain) radiation may help improve survival. ...Read more

See 2 more doctor answers
12

12
Is radiation therapy possible for bile duct cancer?

Is radiation therapy possible for bile duct cancer?

Yes: Surgery is the first and most important treatment. Often radiation and chemo will be needed because these cancer can recur easily. ...Read more

See 3 more doctor answers
13

13
Is folfiri alone effective for metastic colon cancer than irinotecan alone ?

Is folfiri alone effective for metastic colon cancer than irinotecan alone ?

Two drugs vs one dru: Folfiri contains two drugs in the combination: 5-FY(Folinic acid) and Irinotecan. This combination is more effective than using irinotecan alone. It is often combined with Avastin (bevacizumab) in case it is being used to treat colon cancer. ...Read more

14

14
How effective is radiation therapy for treating colon cancer?

How effective is radiation therapy for treating colon cancer?

Partially effective: The best approach for colon cancer is resection. If lesion is large such as one in the rectosigmoid, then RT plus chemo can be employed to reduce the lesion for resection. While the end effect minimizes local recurrence, it does not alter overall survival. ...Read more

15

15
Prognosis for hormone refractory metastatic prostate cancer with pathological fracture?

Prostate cancer: This is an advanced stage of prostate cancer; the good news is there are many new drugs and treatments for men in this stage that have been shown to extend life; in this stage survival is extremely variable from months to years isn't impossible. ...Read more

See 1 more doctor answer
16

16
Treatments for prostate cancer with bone metastasis?

Treatments for prostate cancer with bone metastasis?

Many: The first line of treatment for this is androgen deprivation. In addition, there are medicines which reduce the risk of fractures with Denosumab showing the most efficacy compared to zoledronic acid, however with some risk of significant side effects. For more extensive disease, a newer IV radium therapy has shown improved survival. Localized radiation can be effective for painful foci. ...Read more

See 1 more doctor answer
17

17
Is brachytherapy helpful for a prostate cancer patient who has metastasized cancer cells?

Is brachytherapy helpful for a prostate cancer patient who has metastasized cancer cells?

No.: Brachytherapy is used in the treatment of localized prostate cancer, or cancer that has not spread outside of the prostate gland. If a patient has metastatic disease, treatments need to be systemic, with the aim of halting the growth & spread of the cancer throughout the body. These treatments include hormonal therapy, chemotherapy, and immunotherapy. Urologists & medical oncologists can help. ...Read more

See 2 more doctor answers
18

18
How effective is radiation therapy for breast cancer?

How effective is radiation therapy for breast cancer?

Very effective.: Radiation therapy (rt) is never a primary treatment for breast cancer, but rather a supplement to surgery for the local treatment of breast cancer. Rt is mandatory following breast conserving surgery: local recurrence rates are decreased from >25% to <5% with rt. Rt is also used after mastectomy for patients that are at high risk for local recurrence. ...Read more

See 2 more doctor answers
19

19
Experts, might someone recommend nexavar (sorafenib) for a stage 4 inactive neuroendocrine pancreatic cancer patient?

Experts, might someone recommend nexavar (sorafenib) for a stage 4 inactive neuroendocrine pancreatic cancer patient?

Possibly: Stage 4 indicates that you have net at a site distant from the pancreas or regional lymph node, likely the liver. Not clear what you mean by"inactive", whether you mean it is stable or not secreting any substance. In any case, sorafenib (nexavar) is being tested in metastatic net in clinical trials (http://clinicaltrials.Gov/ct2/show/nct00131911) & (http://www.Ncbi.Nlm.Nih.Gov/pubmed/23475104). ...Read more

See 1 more doctor answer
20

20
Can Radiotherapy be used for metastic colon cancer if chemotherapy is resistant ?

Not often: Radiotherapy can be useful in certain select cases where the Cancer is localized to one or two spots only. This means 1 patient in 5 may be suitable candidate. But you need to seek consultation with a radiation oncologist before you can get a clear cut answer for your circumstances. ...Read more

See 1 more doctor answer

Neoadjuvant (Definition)

Neoadjuvant therapy is the administration of therapeutic agents before a main treatment. One example is neoadjuvant hormone therapy prior to radical radiotherapy for adenocarcinoma of the prostate. Neoadjuvant therapy aims to reduce the size or extent of the cancer before using radical treatment intervention, thus making procedures easier and ...Read more


Dr. Barbara Lavi
3 doctors shared insights

Pancreas (Definition)

Abdominal organ. It is digestive organ: it secretes enzymes into the small bowel which break down food and help its absorption. It is also an endocrine organ: it produces hormones involved in sugar control and control of digestion. Insulin is one of these hormones. Diabetics either lack Insulin (type 1 diabetes) or have inadequate ...Read more