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Doctor insights on: Neoadjuvant Chemotherapy Breast Cancer

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How effective is chemotherapy for treating breast cancer?

How effective is chemotherapy for treating breast cancer?

Very effective: Chemo initially started with combinations like CMF and then changed to combinations of antibody plus chemo such as taxol plus Herceptin (trastuzumab). These drugs alone and in combination best used as a neoadjuvant prior to surgical resection or when at high risk in the adjuvant setting to prevent recurrence. Once metastasis happens, there can be chemo control but cure is rare. ...Read more

Dr. Barry Rosen
1,336 doctors shared insights

Breast Cancer (Female) (Definition)

Breast cancer results when glandular cells lining the milk ducts and lobules of the human breast begin to grow in an unregulated manner. The growth occurs initially inside the ducts but eventually breaks outside into the breast tissue and ultimately spreads both to the lymph nodes in the armpit and via the bloodstream to other parts of the body. Because of the promoting affect of estrogen almost all breast cancer occurs in women and is a rarity in men. The unregulated growth is due to both inherited and acquired genetic defects. It is the most common malignancy in women but it often curable if found early and treated effectively with surgery, hormonal therapy, chemotherapy and targeted therapy, or a combination thereof. Early detection before the malignancy becomes large enough to be felt depends on mammography/sonography and MRI imaging of the breast on an annual basis. ...Read more


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Should someone go through chemotherapy if she has breast cancer?

Should someone go through chemotherapy if she has breast cancer?

Maybe: As with most other cancers, it depends on many factors but it would be safe to say that in certain situations, chemo is an integral part of the treatment for breast cancer. You need to talk to an oncogist about it. The goals of therapy should justify the potential toxicity. Best regards. ...Read more

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How to boost white blood counts during chemotherapy for breast cancer?

How to boost white blood counts during chemotherapy for breast cancer?

"growth factors": Your oncologist can use bone marrow growth factors ("gcsf") to stimulate production of white blood cells. These drugs, developed and tested in the 1980's, became available in the ~spring of 1991 and (along with drugs to treat/prevent nausea) completely changed the field of oncology. It went from being a mostly inpatient discipline, to one almost entirely practiced in the outpatient setting. ...Read more

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What are other options other than chemotherapy for stage 2 breast cancer?

What are other options other than chemotherapy for stage 2 breast cancer?

Depends: This depends on the type of breast cancer you have. Treatment is now individualized to the type of cancer, lymph node involvement and hormone status of the cancer cells. A special test called a oncotype DX can help determine if chemotherapy is beneficial or not but the cells have to have hormone receptors. I recommend speaking with your oncologist. Don't be afraid to get a 2nd opinion. ...Read more

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Is it possible there is a way to keep my hair with breast cancer chemotherapy?

Is it possible there is a way to keep my hair with breast cancer chemotherapy?

YES! Peguin Caps!: They are expensive and annoying, but they work really well. Here is their website: https://penguincoldcaps.Com/. ...Read more

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Could you give me some advice about a portacath for breast cancer chemotherapy?

Could  you give me some advice about a portacath for breast cancer chemotherapy?

Minor pricedure: Minor surgical procedure for insertion. Small chamber under the akin attached to a catheter that goes into a main vein. Oncologist or their nurse inserts a needle through the skin into the port to deliver the medications. No specific patient care needs. The port can be removed when no longer needed. ...Read more

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Could you tell me what are other options other then chemotherapy for stage 2 breast cancer?

Could you tell me what are other options other then chemotherapy for stage 2 breast cancer?

"Options": The standard and recommended treatment in premenopausal patients would usually included chemotherapy and an anti-hormone regimen. Chemo is only used in about 15% of postmenopausal women, those who have hormone negative tumors. Radiation is used in breast sparing procedures, and is used to supplement mastectomy patients. If you are unsure, get a second oncological opinion. Good luck. ...Read more

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Does chemotherapy work for breast cancer?

Does chemotherapy work for breast cancer?

It depends: Chemo treats the whole body to kill cancer cells that may have escaped from the breast tumor. Sometimes chemo is used to shrink the breast tumor before surgery (neoadjuvant chemotherapy). Breast cancers that respond best to chemotherapy are those with a high ki-67 (proliferation rate), er negative, and/or her2 positive. ...Read more

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What sorts of chemotherapy are most common for breast cancer?

What sorts of chemotherapy are most common for breast cancer?

Many diff regimens: There are many different regimens utilizing multiple drugs and ranging 3-6 months. Common drugs are anthracyclines, taxanes, and Cytoxan (cyclophosphamide) in various combinations - acx4, tcx4(or 6), tac x 6, acx4 ->tx4, dose dense ac->t, weekly taxol. Other options/drugs can also be considered in the metastatic setting. A patient should seek a medical oncologist experience in breast to rec the best regimen. ...Read more

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Dr. Barry Rosen
4,214 doctors shared insights

Cancer (Definition)

Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more


Neoadjuvant (Definition)

Neoadjuvant therapy is the administration of therapeutic agents before a main treatment. One example is neoadjuvant hormone therapy prior to radical radiotherapy for adenocarcinoma of the prostate. Neoadjuvant therapy aims to reduce the size or extent of the cancer before using radical treatment intervention, thus making procedures easier and ...Read more