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Doctor insights on: Neoadjuvant Chemotherapy Breast Cancer

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How effective is chemotherapy for treating breast cancer?

How effective is chemotherapy for treating breast cancer?

Very effective: Chemo initially started with combinations like CMF and then changed to combinations of antibody plus chemo such as taxol plus Herceptin (trastuzumab). These drugs alone and in combination best used as a neoadjuvant prior to surgical resection or when at high risk in the adjuvant setting to prevent recurrence. Once metastasis happens, there can be chemo control but cure is rare. ...Read more

Dr. Barry Rosen
4,316 doctors shared insights

Cancer (Definition)

Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more


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Should someone go through chemotherapy if she has breast cancer?

Should someone go through chemotherapy if she has breast cancer?

Maybe: As with most other cancers, it depends on many factors but it would be safe to say that in certain situations, chemo is an integral part of the treatment for breast cancer. You need to talk to an oncogist about it. The goals of therapy should justify the potential toxicity. Best regards. ...Read more

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How to boost white blood counts during chemotherapy for breast cancer?

How to boost white blood counts during chemotherapy for breast cancer?

Growth factors: If your blood counts are severely low then use of growth factor injections(neulasta (pegfilgrastim) or neupogen) can help boost the recovery of your blood counts after chemotherapy. ...Read more

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What are other options other than chemotherapy for stage 2 breast cancer?

What are other options other than chemotherapy for stage 2 breast cancer?

Depends: This depends on the type of breast cancer you have. Treatment is now individualized to the type of cancer, lymph node involvement and hormone status of the cancer cells. A special test called a oncotype DX can help determine if chemotherapy is beneficial or not but the cells have to have hormone receptors. I recommend speaking with your oncologist. Don't be afraid to get a 2nd opinion. ...Read more

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Could you give me some advice about a portacath for breast cancer chemotherapy?

Could  you give me some advice about a portacath for breast cancer chemotherapy?

Minor pricedure: Minor surgical procedure for insertion. Small chamber under the akin attached to a catheter that goes into a main vein. Oncologist or their nurse inserts a needle through the skin into the port to deliver the medications. No specific patient care needs. The port can be removed when no longer needed. ...Read more

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Could you tell me what are other options other then chemotherapy for stage 2 breast cancer?

Could you tell me what are other options other then chemotherapy for stage 2 breast cancer?

"Options": The standard and recommended treatment in premenopausal patients would usually included chemotherapy and an anti-hormone regimen. Chemo is only used in about 15% of postmenopausal women, those who have hormone negative tumors. Radiation is used in breast sparing procedures, and is used to supplement mastectomy patients. If you are unsure, get a second oncological opinion. Good luck. ...Read more

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Does chemotherapy work for breast cancer?

Does chemotherapy work for breast cancer?

It depends: Chemo treats the whole body to kill cancer cells that may have escaped from the breast tumor. Sometimes chemo is used to shrink the breast tumor before surgery (neoadjuvant chemotherapy). Breast cancers that respond best to chemotherapy are those with a high ki-67 (proliferation rate), er negative, and/or her2 positive. ...Read more

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What sorts of chemotherapy are most common for breast cancer?

What sorts of chemotherapy are most common for breast cancer?

Many diff regimens: There are many different regimens utilizing multiple drugs and ranging 3-6 months. Common drugs are anthracyclines, taxanes, and Cytoxan (cyclophosphamide) in various combinations - acx4, tcx4(or 6), tac x 6, acx4 ->tx4, dose dense ac->t, weekly taxol. Other options/drugs can also be considered in the metastatic setting. A patient should seek a medical oncologist experience in breast to rec the best regimen. ...Read more

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How effective is the TAC chemotherapy regimen for treating breast cancer?

How effective is the TAC chemotherapy regimen for treating breast cancer?

Very!: TAC stands for Taxotere, Adriamycin, (doxorubicin) and Cyclophosphamide. It is one of the strongest regimens for treating breast cancer, and some would say too strong. Depending on the type of breast cancer you have, or the stage, you might be able to receive a gentler regimen. If you want to know more, get a second opinion. ...Read more

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How long is the chemotherapy for a stage 2a node negative breast cancer?

How long is  the chemotherapy for a stage 2a node negative breast cancer?

It depends: There are several chemotherapy options for stage 2a breast cancer. Characteristics of the patient and the cancer are required to make a decision on the type of chemotherapy (and whether chemotherapy is even necessary). Chemotherapy would be anywhere from about 8 weeks to a year (herceptin-or trastuzumab treatment, if recommended, requires a year of treatment). ...Read more

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How can I support my friend who has undergone chemotherapy for breast cancer?

How can I support my friend who has undergone chemotherapy for breast cancer?

Do support her: She may need your emotional support and other help. Go meet her and ask if you can help her with any probelms or issues of concern to her. She would appreciate your concern for her welfare and your offer to help her.Just the company of a good friend can be a big morale booster. ...Read more

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Please tell me what are other options besides chemotherapy for breast cancer?

Please tell me what are other options besides chemotherapy for breast cancer?

It depends: It depends on the type of breast cancer. If positive for estrogen and/or Progesterone receptors ("er" and "pr") there are other options, though in some cases it may not be as good as taking these meds in conjunction with chemo. If stage 4 breast cancer, there are many clinical trials. Again, it depends on the cancer stage, and the markers er/pr, and her2 from the cancer specimen. ...Read more

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I'm just wondering, if you opt out for chemotherapy for breast cancer what is the process you go through?

I'm just wondering, if you opt out for chemotherapy for breast cancer what is the process you go through?

Not sure if 'opt: Out' means 'refuse' or 'decide to stop'. Either is a serious decision that requires discussion with 1 or more medical oncologists. The 'oncotype' process defines benefit and risk of chemo in some. However, depending on many factors (size, nodal status, receptors), the consequences vary. Perfect for second or third opinion. ...Read more

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Hormonal effects of chemotherapy for breast cancer?

Please clarify.: It is unclear from your question what you are asking. Most breast cancers are estrogen-sensitive and can be treated with anti-estrogen medication (tamoxifen, aromatase inhibitors). Many women who are peri menopausal when receiving traditional chemotherapy develop ovarian suppression from the chemo and effectively "go into" menopause. I hope this helps. ...Read more

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Is there cardiac failure risk involved in breast cancer chemotherapy?

Yes: Chemotherapy may affect heart function, for that reason a nuclear study of the heart is done before starting some type of chemotherapy for breast cancer. ...Read more

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Is it possible there is a way to keep my hair with breast cancer chemotherapy?

Is it possible there is a way to keep my hair with breast cancer chemotherapy?

YES! Peguin Caps!: They are expensive and annoying, but they work really well. Here is their website: https://penguincoldcaps.Com/. ...Read more

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Patients with advanced breast cancer,Has received chemotherapy,Is there any need for radiotherapy?

Patients with advanced breast cancer,Has received chemotherapy,Is there any need for radiotherapy?

Breast Cancer: As you see on TV cancer Dx and Rx is very individualized. Some need radiation and some may not. So discuss this with your Dr. ...Read more

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Im a breast cancer positive, stage 1 with her2 positive, is completly necesary the chemotherapy in my case?

Breast CA: It really depends on your risk factors and tumor characteristics. You should have a through consultation with a medical oncologist to determine the best course. ...Read more

Dr. Barry Rosen
1,365 doctors shared insights

Breast Cancer (Definition)

Occurs when glandular cells lining the milk ducts and lobules of the human breast begin to grow in an unregulated manner. Often curable if found early and treated effectively with surgery, hormonal therapy, chemotherapy and targeted therapy, or a combination thereof. Early detection before the malignancy becomes large enough to be felt depends on mammography/sonography and MRI imaging of the breast ...Read more


Neoadjuvant (Definition)

Neoadjuvant therapy is the administration of therapeutic agents before a main treatment. One example is neoadjuvant hormone therapy prior to radical radiotherapy for adenocarcinoma of the prostate. Neoadjuvant therapy aims to reduce the size or extent of the cancer before using radical treatment intervention, thus making procedures easier and ...Read more