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Doctor insights on: Neoadjuvant Chemo For Breast Cancer

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Colon cancer chemo necessary?

Colon cancer chemo necessary?

Depends on stage: Chemotherapy is never used for stage 1 cancers (early). It is sometimes used in stage 2 cancers (early but more advanced than stage 1). Chemotherapy is definitely beneficial in stage 3 cancers (locally advanced) and in stage 4 cancers (distant spread). ...Read more

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Dr. Barry Rosen
4,364 doctors shared insights

Cancer (Definition)

Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more


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Does chemotherapy work for breast cancer?

Does chemotherapy work for breast cancer?

It depends: Chemo treats the whole body to kill cancer cells that may have escaped from the breast tumor. Sometimes chemo is used to shrink the breast tumor before surgery (neoadjuvant chemotherapy). Breast cancers that respond best to chemotherapy are those with a high ki-67 (proliferation rate), er negative, and/or her2 positive. ...Read more

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Compare and contrast chemotherapy for aml with chemo for prostate cancer?

Compare and contrast chemotherapy for aml with chemo for prostate cancer?

Different drugs. : Chemotherapy for a hematologic cancer such as AML differs in the drugs & regimens from an epithelial cancer like prostatic carcinoma. AML typically uses Cytarabine and an anthracycline on a specific schedule. In prostate cancer, docetaxel and cabazitaxel are frequently used drugs. Of note, chemotherapy is not as common a treatment for prostate cancer, where hormonal therapy is often used. ...Read more

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How effective is Xeloda (capecitabine) for metastatic breast cancer?

How effective is  Xeloda (capecitabine) for metastatic breast cancer?

It depends: As the first treatment for metastatic breast cancer, Xeloda (capecitabine) works in 40-60% of people treated. If it is the second, third or later treatment after failure of other agents, the effectiveness is much less. ...Read more

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Dr. Liawaty Ho Dr. Ho
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Chemotherapy hormone receptor positive node breast cancer?

Dr. Liawaty Ho Dr. Ho
4 doctors agreed:
Chemotherapy hormone receptor positive node breast cancer?

D/W oncologist: Treatment will depend not only the stage but also the biology of the cancer- whether it is estrogen positive, her2neu positive, whether it is lymph node positive or not. Also depends on your preference and overall health condition. Different test like oncotype dx, mammaprint can give you more info-re- recurrence risk of cancer and will be helpful in choosing the right therapy for you.D/w your md. ...Read more

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Stage 2B IDC breast cancer, her2+/ER/PR+Neoadjuvant taxol, (paclitaxel)A/C,lumpectomy,rads, lymphovascular invasion. What does this mean for prognosis & follow up?

Stage 2B IDC breast cancer, her2+/ER/PR+Neoadjuvant taxol, (paclitaxel)A/C,lumpectomy,rads, lymphovascular invasion. What does this mean for prognosis & follow up?

Prognosis fair: Stage IIb breast cancer is usually palpable at 2-5 cm. and at time of procedure to remove lesion, sentinel nodes are + suggesting axillary dissection and reason for neoadjuvant therapy. Lymphovascular invasion increases chance for recurrence. With Her2+ Herceptin (trastuzumab) with chemo should be used and PET/CAT needed to assure met foci not missed in distal organs. Carful follow up needed. ...Read more

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Is radiation effective for breast cancer?

Is radiation effective for breast cancer?

Very effective.: Radiation therapy (rt) is never a primary treatment for breast cancer, but rather a supplement to surgery for the local treatment of breast cancer. Rt is mandatory following breast conserving surgery: local recurrence rates are decreased from >25% to <5% with rt. Rt is also used after mastectomy for patients that are at high risk for local recurrence. ...Read more

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Hormonal effects of chemotherapy for breast cancer?

Hormonal effects of chemotherapy for breast cancer?

Please clarify.: It is unclear from your question what you are asking. Most breast cancers are estrogen-sensitive and can be treated with anti-estrogen medication (tamoxifen, aromatase inhibitors). Many women who are peri menopausal when receiving traditional chemotherapy develop ovarian suppression from the chemo and effectively "go into" menopause. I hope this helps. ...Read more

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How effectice is Xeloda (capecitabine) for metastatic breast cancer?

Quite effective: Xeloda (capecitabine) is quite an effective drug and has been used in metastatic breast cancer. The response will be higher when it is combined with other chemotherapy agent- with additional possible side effects. Discuss further with you oncologist in detail. ...Read more

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When is tamoxifen for breast cancer treatment?

When is tamoxifen for breast cancer treatment?

Chemotherapy: Tamoxifen is a very effective drug for the treatment of hormone-sensitive (estrogen receptor +) breast cancers. It may be used alone or in combination with traditional IV chemotherapy, depending on the cancer stage. Furthermore, tamoxifen has been shown to be effective reducing the chance of developing breast cancer in high-risk women ("chemoprevention"). ...Read more

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Estrogen receptor ER positive breast cancer adjuvant Taxol (paclitaxel) benefits?

Estrogen receptor ER positive breast cancer adjuvant Taxol (paclitaxel) benefits?

Get Oncotype: In order to answer this question, more details are needed (size of tumor, lymph node involvement, etc). A test that will help to decide if you need chemotherapy or not is the oncotype dx. I highly recommend you speak with your oncologist and even consider a 2nd opinion. ...Read more

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Dysphagia and chemotherapy for colon cancer?

Dysphagia and chemotherapy for colon cancer?

It depends ... : Dysphagia is a common side effect with many chemo therapeutic regimens. Some treatments can decrease a patient's ability to fight off fungal and bacterial overgrowth in the mouth and digestive systems. The diagnosis of this isn't usually difficult and can in many cases be treated with medications. ...Read more

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Is Xeloda (capecitabine) effective for breast cancer?

Is Xeloda (capecitabine) effective for breast cancer?

Xeloda (capecitabine) for breast ca: Xeloda (capecitabine) also known as Capecitabine is a very effective oral chemotherapy drug used for metastatic or stage 4 breast cancer. It can be used by itself (mono therapy) or as part of combination chemotherapy. Major side effects include diarrhea, hand foot syndrome, nausea and small chance of coronary spasm. It is well tolerated. Patients on Xeloda (capecitabine) need to be followed closely by medical oncologists. ...Read more

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Dr. Liawaty Ho Dr. Ho
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How effective iressa (gefitinib) for lung cancer after chemo?

Dr. Liawaty Ho Dr. Ho
5 doctors agreed:
How effective iressa (gefitinib) for  lung cancer after chemo?

Only if ..: Gefitinib will only work if there is a egfr mutation detected on the cancer. It will not be effective if there is no egfr mutation detected. ...Read more

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Can radiation therapy for breast cancer give me leukemia?

Can radiation therapy for breast cancer give me leukemia?

Not likely: Leukemia is more likely as a cancer caused by chemotherapy since it exposes more bone marrow. Radiation to the breast will expose very little bone marrow and leukemia is not likely but nothing is impossible. ...Read more

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How is stage IV breast cancer different from stage III breast cancer?

How is stage IV breast cancer different from stage III breast cancer?

Location: In stage iii, the cancer still hasn't spread far beyond the breast and nearby lymph nodes. However, in this stage there typically are many lymph nodes involved or the tumor is so large it extends to the chest wall or involves the skin of the breast. stage IV breast cancer has spread to distant sites of the body. ...Read more

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Adjuvant tamoxifen or other chemotherapy for ER pr negative cancer?

Adjuvant tamoxifen or other chemotherapy for ER pr negative cancer?

Chemotherapy: Tamoxifen is only used for patients whose tumors are positive for er and/or pr. ...Read more

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Do people with stage IV metastatic breast cancer often undergo chemo?

Do people with stage IV metastatic breast cancer often undergo chemo?

Yes.: Under certain circumstances hormone therapy might be the initial treatment, but most stage 4 patients eventually undergo chemotherapy treatment. This will depend on age, tolerence for treatment, hormone responsiveness and other tumor characteristics. ...Read more

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What is prognosis With chemotherapy for metastic colon Cancer ?

What is prognosis With chemotherapy for metastic colon
Cancer ?

So many variables: Too many variables to give you a pertinent answer. Consult your oncologist to help you with clinical decisions ...Read more

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Chemo drugs for lung cancer ?

Chemo drugs for lung cancer
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Yes: Depending on the stage, how advanced the disease is and what type of lung cancer it is, chemotherapy can play a major role in treatment of lung cancer. ...Read more

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Neoadjuvant (Definition)

Neoadjuvant therapy is the administration of therapeutic agents before a main treatment. One example is neoadjuvant hormone therapy prior to radical radiotherapy for adenocarcinoma of the prostate. Neoadjuvant therapy aims to reduce the size or extent of the cancer before using radical treatment intervention, thus making procedures easier and ...Read more


Dr. Mark Hoepfner
1,065 doctors shared insights

Breast Carcinoma (Definition)

Most breast cancers are carcinomas. This is a type of breast cancer. These cancers start in the cells that line organs and tissues. In fact, breast cancers are often a type of carcinoma called adenocarcinoma, which starts in cells that make glands (glandular tissue). Breast adenocarcinomas start in the ducts (the milk ducts) or ...Read more