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Doctor insights on: Negli Aplastic Anemia

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Can neglis aplastic anemia be cured?

Can neglis aplastic anemia be cured?

What is neglis?: Regarding aplastic anemia, yes there are good treatments for it. Standard of care for a young person with severe aplastic anemia and a matched sibling donor is an hematopoietic stem cell transplant. For those without a suitable donor, immune suppression is standard of care. If you can clarify the word "neglis" for us, we are happy to provide additional info. Cheers. ...Read more

Dr. Steven Ginsberg
1,276 doctors shared insights

Anemia (Definition)

Any condition where there is a decrease in the red blood ...Read more


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Is polychromasia typically associated with microcytic anemia (iron deficient anemia)?

Is polychromasia typically associated with microcytic  anemia (iron deficient anemia)?

Iron deficiency is: Usually hypo chromic. Polychromasia is seen in rapidly changing circumstances like hemolytic anemia. ...Read more

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Can sickle cell anemia be fatal?

Can sickle cell anemia be fatal?

Yes: Individuals with sickle cell anemia are at high risk to develop invasive bacterial infections, e.g., meningitis and bacteremia, especially by pneumococcus. Penicillin prophylaxis, immunization, and prompt medical attention for febrile illness have greatly reduced fatality from serious infection. ...Read more

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Why is iron deficiency anemia a microcytic anemia?

Why is iron deficiency anemia a microcytic anemia?

Decreased Hemoglobin: Red blood cells (rbcs) are essentially little bags carrying lots of hemoglobin (hb). Iron is an important constituent of the hb molecule. Low iron = low hemoglobin = less packing into rbc. Since the RBC is now filled less, a microcytic anemia results. ...Read more

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How serious is iron deficiency anemia?

How serious is iron deficiency anemia?

Severity and cause: Will depend on how severe it is and whether you are pregnant or not. If you only have mild deficiency-you probably don't have any symptom. If severe enough, tired, fatigue, dizziness, chest pain, shortness of breath can be the symptoms. In pregnancy iron is very important for the fetus. It is crucial to know what is the cause. Bleeding? Malabsorption, cancer? Etc- this needs to be found out. ...Read more

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Can Lamotrigine cause aplastic anemia?

Unfortunately, yes: Unfortunately, the very good drug for epilepsy and to some extent mood disorders, Lamotrigine can cause aplastic anemia in a very rare number of individuals. AA is present worldwide at a rate of about 4 cases per 1 million (word wide). 3.2 cases per million would be ACQUIRED such as from exposure to medication or other reasons. Usually found in younger individuals on the drug. ...Read more

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Why MCHC is low in iron deficiency anemia but normal in pernicious anemia?

Why MCHC is low in iron deficiency anemia but normal in pernicious anemia?

MCHC: MCHC=mean corpuscular hemoglobin concentration This value is a calculated value of hemoglobin per red cell. In iron deficiency the body has difficulty making enough hemoglobin, and the resultant cells are both small and low on hgb. The defect with PA is not with hgb synthesis but with cell replication and nuclear maturation, so the amount of hgb/cell is unaffected. ...Read more

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Can normochromic or normocytic anemia cause leukemia?

Can normochromic or normocytic anemia cause leukemia?

No: Anemia (normochromic/cytic or not) can be a sign of leukemia (or a variety of other cancerous or non-cancerous conditions). That is it can associated with leukemia. However, it does not cause leukemia. Correlation does not equal causation. ...Read more

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28wks pregnant with hypothyroidism.Low = haemoglobin, platelets, RBC, haematocrit &lymphocytes. High MCH, MCV quite high. Anaemia? or possible cause?

28wks pregnant with hypothyroidism.Low = haemoglobin, platelets, RBC, haematocrit &lymphocytes. High MCH, MCV quite high. Anaemia? or possible cause?

Anemia and pregnancy: Being pregnant can cause anemia. Discuss with your obstetrician. It also depends what your haemoglobin was before you were pregnant. ...Read more

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Is sickle cell anemia hereditary?

Is sickle cell anemia hereditary?

Yes.: it is an autosomal recessive disorder, meaning that both parents must be carriers of the mutation. If they are, the chance of each child being affected is 1 in 4. ...Read more

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Does nomochromic normocytic anemia indicate renal impairment?

Does nomochromic normocytic anemia indicate renal impairment?

Not necessarily: Normocytic normochromic anemia can be caused by acute blood loss, early iron deficiency, bone marrow supression, anemia of chronic disease, anemia of renal insufficiency, anemia caused by endocrine problem etc. ...Read more

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Ferritinin 800, iron 167. And macrocytic anemia. Liver , kidney, wbc, platelets, neutrophil, B12 normal. Why? Is it preleukemia?

Ferritinin 800, iron 167. And macrocytic anemia. Liver , kidney, wbc, platelets, neutrophil, B12 normal. Why? Is it preleukemia?

At least 2 problems: You realize that we can't diagnose you. With the very high serum ferritin and up-there serum iron, assuming the blood was not drawn during an acute illness, you have hemochromatosis until proved otherwise. How anemic you are, whether this is real macrocytosis, what your physical findings and other labs are are best known to your hematology consultation. Hope nobody gave you iron supplements. ...Read more

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How dangerous is sickle cell anemia?

More info needed: Patients with sickle cell anemia have greater tendency for severe anemia and infection. Usually children have more difficulties. Sometimes frequent transfusion is needed to assist in crises, or to suppress sickle hemoglobin and decrease sickling issues which can be very painful. Hydroxyurea is used to help symptoms and to increase fetal hemoglobin, vaccinations, and antibiotics help. See MD. ...Read more

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Anemia? iron deficiency, blood loss or chronic illness? WBC 10.9, RBC 3.73, Hemo 117, Iron 10, TIBC 53, Ferritin 49, iron sat 0.19, urine protein 0.15

Anemia? iron deficiency, blood loss or chronic illness? WBC 10.9, RBC 3.73, Hemo 117, Iron 10, TIBC 53, Ferritin 49, iron sat 0.19, urine protein 0.15

Looks: Like iron deficiency green leafy vegetables are good b12 for good measure. But follow up with your doctor if you are losing body as in heavy menstrual bleeding or gi bleeding ...Read more

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Severe iron deficient anemia 12 yrs.mvp.new diagnosis of hepc.headaches.swollen spre tounge.require IV iron q 4mo. 417 IgM 8.2hgb 25hct iron low of 12. progn?

Severe iron deficient anemia 12 yrs.mvp.new diagnosis of hepc.headaches.swollen spre tounge.require IV iron q 4mo. 417 IgM 8.2hgb 25hct iron low of 12. progn?

Probably excellent: If society is wise enough to provide the new hepatitis C treatment to everyone at a reasonable cost, getting rid of hepatitis C will probably benefit you greatly. You need to find out why you are iron deficient -- a workup by a competent physician is in order, checking for malabsorption, ulcer, hookworm, tumor, more. Once done this will help greatly. ...Read more

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Does pernicious anemia cause high serum b12?

Low vitamin B12.: pernicious anemia is a LOW vitamin B12 state. This occurs when the body fails to make enough of a specific protein to enable the body to absorb vitamin B12. This usually occurs when the immune system attacks a specific cell in the stomach that produces the needed protein. Since the body can't absorb vitamin B12 through the stomach it can be given in a shot and even under the tongue. ...Read more

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Does autoimmune hemolytic anemia affect WBC ?

Does autoimmune hemolytic anemia affect WBC
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Not usually: It depends on the type of autoimmune disorder. In most cases autoimmune hemolytic anemia does not affect WBC. But some autoimmune disorders like SLE may cause hemolytic anemia and neutropenia as well. ...Read more

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I have iron deficiency anemia. Current bloodwork: Transferrin 379, iron 120, TIBC 565, iron saturation 21.2. Hgb 8.9, above results still anemia??

Yes indeed: Hemoglobin 8.9 is anemia, period. Please forgive my frankness. I hope that no one is forcing you to be a non-supplementing vegetarian. If you have blood loss, either monthly or from illness, I hope the source is discovered -- it could be ulcer, cancer, hookworm, etc. If you tolerate oral iron poorly, please consider an injectable form. Best wishes. ...Read more

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Ferritin13, Iron167, TIBC496, Transferrin392, %Sat.34, Hemoglobin13.9 Is this anemia or iron overload?

Ferritin13,  Iron167, TIBC496, 
Transferrin392, %Sat.34, Hemoglobin13.9
Is this anemia or iron overload?

Neither: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, the data you provided suggests that your iron stores at the low end, but you are not anemic.
For good health - Have a diet rich in fresh vegetables, fruits, whole grains, milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Drink enough water daily, so that your urine is mostly colorless. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form.
Practice safe sex, if you have sex. ...Read more

Dr. Keith Stockerl-Goldstein
79 doctors shared insights

Anemia, Aplastic (Definition)

Complete lack of blood cell reproduction. ...Read more