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Need To Biliary Cirrhosis
I need information on primary biliary cirrhosis I am a 69 year female was diagnosed in 2010. What is the best test to confirm the disease. And where would be the best place for a second opinion? What should I look for as signs of progessing in the dise
Liver biopsy: Is the gold standard, and a diagnosis cannot really be made without it, although blood tests, scans and medical history/family history can strongly suggest it. Most major medical centers. Like emory university hospitals in atlanta, have liver specialists who further sub-specialize in primary biliary cirrhosis. Increasing fatigue is most common symptom of progression, with jaundice and itching. ...Read moreSee 1 more doctor answer
Liver problems: With primary biliary cirrhosis the small bile ducts in the liver are affected. As time goes on cirrhosis of the liver can result. This results in jaundice and itching. As cirrhosis worsens people have issues with enlarged veins around the esophagus, stomach and rectum. These can cause severe bleeding. Also complete liver failure can result. ...Read moreSee 1 more doctor answer
Autoantibody &Biopsy: In addition to abnormal blood tests due to malfunction of liver, patients with primary biliary cirrhosis have peculiar autoantibodies, anti-mitochondrial antibodies. Blood tests and imaging suggest cirrhosis, confirmation requires biopsy (usually needle biopsy) and examination of the tissue by a pathologist. ...Read more
Bad if untreated: An immuno-genetic disease, of which 90% are female, typically 40-60 years old. The disease affects asians, caucasians, jews, african. Family clustering is common. Early symptoms are fatigue, itching before jaundice, RUQ pain. Untreated pbc leads to progressive liver failure with its sequelae. Advanced age, liver/spleen enlargement, ascites, low albumin, fibrosis, cirrhosis predict worst prognosis. ...Read more
Depends: The degree or severity of the cirrhosis determines what symptoms are present. Early cirrhosis can not cause any symptom. Severe cirrhosis can cause many symptoms including but not limited to bleeding, fluid build up in the abdomen, turning yellow skin and eyes, death. ...Read moreSee 1 more doctor answer
Family risks for PBC: 90% of pbc patients are female. Age ranges 20-80, but typically patients are 40-60. The disease is world-wide, & affects asians, caucasians, jews, african. Family clustering is common in sisters, twins, daughters, mothers. While environmental factors can't be ignored, a strong immunogenetic background for pbc that runs in families is suggested. Early sxs: fatigue, itching before jaundice, RUQ pain. ...Read more
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