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Doctor insights on: Necrosis

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Necrosis (Overview)

Necrosis is the the death of cells and tissue. In dentistry, root canals are often needed when the pulp tissue inside a tooth has gone necrotic.


Necrosis (Overview)

Necrosis is the the death of cells and tissue. In dentistry, root canals are often needed when the pulp tissue inside a tooth has gone necrotic.


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What can cause nerve necrosis?

Many concerns: Necrosis is "death" or destruction of a nerve, and this sometimes is necessitated to alleviate pain, by an alcohol injection. If a nerve is cut or transected, or if a nerve cell body dies (apoptosis), from a variety of inflammatory or degenerative causes, recovery is not possible. So, nerve death can occur both in central and peripheral nervous systems. Timely treatment is always best. ...Read more

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What is the definition or description of: necrosis?

Cell / tissue death: Necrosis is the death of cells and tissue. In dentistry, root canals are often needed when the pulp tissue inside a tooth has gone necrotic. ...Read more

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What is a decreased necrosis and is it bad. Can you also tell me how to cure it.

Ok...clarify: Where, when, in what context? Decrease of necrosis means less of cell death/damage/destruction......which is always good. ...Read more

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How long can fat necrosis last?

Depends: Upon the cause. There's a rare autoimmune disease which is sort of lifelong but goes dormant with intense immunosuppression.
There's necrosis from infection, trauma, surgical trauma and these don't last long at all if the underlying problem stops. ...Read more

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Extensive tumor necrosis! How to diagnose, what to do?

Remove if possible: When tumor get very large and essentially loose blood supply necrosis can set in. If extensive, tumor necrosis syndrome develops and release of toxins into the blood stream can occur. At this point debulking of the lesion is beneficial. ...Read more

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I was told I have papilary necrosis what does that mean?

Renal disease: Kidney tissue is damaged and is not functioning correctly.

You need to take stock of all medication you have been taking and stop any that has an effect on the kidney. Also, deal with any kidney infection.

Medical care is important and following advise very closely to avoid progression of the condition is essential. ...Read more

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How do subarachnoid haemorrhages result in cell necrosis?

Cell death: Necrosis is cell death. Anything that disrupts the complex system that keeps cells alive can cause cell death. Subarachnoid hemorrhage is a bleed in the brain. The pressure from extra blood in a small space can crush cells, and disrupt fragile capillaries that bring oxygen to cells. This, cell death ...Read more

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What is the best test to diagnose or rule out necrosis due to pancreatitis.?

Probably CT scan: Clinical and laboratory criteria to assess inflammatory responses (Ranson grade, Acute Physiology and Chronic Health Evaluation II score) and contrast-enhanced dynamic computed tomography (dynamic CT) imaging to evaluate pancreatic necrosis are frequently used. Not all patients with pancreatic necrosis identified on dynamic CT scanning develop local complications ...Read more

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Does the term degenerative on a pathology report mean the same thing as necrosis?

Does the term degenerative on a pathology report mean the same thing as necrosis?

No: In fact, "degenerative" is a term often used by pathologists to convey that the changes observed in a specimen are different from necrosis. The exact significance of this term varies depending on where the sample was taken from, so discussion with your doctor is important as mentioned. ...Read more

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What is it about cold injury that kills the organs? Could I ng term exposure cause organ necrosis and kill the victim?

What is it about cold injury that kills the organs? Could I ng term exposure cause organ necrosis and kill the victim?

GivinTheColdShoulder: Your question is a bit vague. But generally, if tissue is actually frozen (frostbite), water crystals form inside the cells and that messes-up the works. When thawed, the tissue is mush. If you are talking about hypothermia, the colder you get the slower your metabolism to the point that the lack of energy formation overcomes the overall slowness of the metabolic processes and then the cells die. ...Read more

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What happens to the testicle as it enters necrosis?

Testis: Necrosis means death of the testicle. It eventually shrinks and essentially disappears. If you are concerned about fertility, necrosis of the testicle in the scrotum may lead to production of antibodies that may lead to infertility. ...Read more

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How is a tubular necrosis diagnosed?

ATN: Acute tubular necrosis is classified as a "renal" (i.e. Not pre-renal or post-renal) cause of acute kidney injury. Diagnosis is made by a fena (fractional excretion of sodium) > 3% and presence of muddy casts (a type of granular cast) in urinalysis and by histopathology. ...Read more

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Is fat necrosis or abscess dangerous?

Is fat necrosis or abscess dangerous?

They're different: Fat necrosis is typically painful but jot dangerous. Abscesses can be dangerous if not properly treated. ...Read more

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Can you explain acute tubular necrosis?

Can you explain acute tubular necrosis?

Ischemia, drugs: Acute tubular necrosis (atn) can happen if the kidney has severely reduced blood supply (ischemia).

This could be caused by hypotension (very low blood pressure), volume depletion (as a result of illness or trauma), problems with the blood vessels supplying the kidneys (renal artery blockage), and drugs that affect the flow of blood to the kidneys.

Drugs and toxins can also directly cause atn. ...Read more

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Which test can diagnose pancreatic necrosis?

Imaging: Hi. The blood tests, amylase & lipase (two pancreatic digestive enzymes) can diagnose pancreatitis, but the best rests for pancreatic necrosis are probably imaging. Best imaging for p. necrosis would be CT with contrast. Abdominal MRI with contrast is also excellent, although not done as routinely. Transabdominal ultrasound doesn't see the pancreas super well, by transesophageal ultrasound is good ...Read more

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Does skin necrosis require immediate surgery?

Does skin necrosis require immediate surgery?

Yes, it may: You should be evaluated immediately, hopefully, the skin can be saved! ...Read more

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What are the causes of acute tubular necrosis?

What are the causes of acute tubular necrosis?

Ischemia, drugs: Acute tubular necrosis (atn) can happen if the kidney has severely reduced blood supply (ischemia).

This could be caused by hypotension (very low blood pressure), volume depletion (as a result of illness or trauma), problems with the blood vessels supplying the kidneys (renal artery blockage), and drugs that affect the flow of blood to the kidneys.

Drugs and toxins can also directly cause atn. ...Read more

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I have necrosis of the liver what can I expect?

I have necrosis of the liver what can I expect?

What's the cause?: An elite athlete can kill off huge numbers of his liver cells in a prolonged endurance event and they grow right back with the liver restored perfectly. This also happens after prolonged shock with recovery. If you have a chronic hepatitis (viral, immune) with ongoing cell damage, the outcome is whatever is expected for the hepatitis. Insist your physician tell you what's killing liver cells. ...Read more

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What can you tell me about the tumor necrosis factor?

Cytokine: Tumor necrosis factor was a cytokine first isolated from macrophages and CD4 cells in response to understanding how Coley's toxin worked. It was felt to be the factor that induced destruction of malignancies but when sequenced proved to be the same molecule as cachexin, a chemical produced by tumor like pancreatic cancer that induced cachexia in patients. ...Read more

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What is the role of mitochondria on apoptosis and necrosis?

Apoptosis: You ask and important tough question. I suggest you go online and read the several articles available. It will take some time but will be worth it. If you have difficulty with that please send another request with more specific questions. I think you won't need to but don't be shy. ...Read more

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What is the difference between kidney nephrosis & kidney necrosis?

What is the difference between kidney nephrosis & kidney necrosis?

Protein: Necrosis refers to the death of cells, usually tubular kidney cells, also found though are vascular necrosis with vasculitis and glomerulonephrtis.

Nephrosis refers to the presence of lots of protein in the urine. ...Read more

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What happens to testicle after necrosis? What time needs to shrink?

What happens to testicle after necrosis? What time needs to shrink?

4th time: What are your symptoms? How did you diagnose yourself? There will be a lot of pain but you previously said no pain. Please see doctor if you still have not. Wish you the best. ...Read more

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Hip necrosis and still young please tell me where to turn for help?

Hip necrosis and still young please tell me where to turn for help?

Orthopaedic Surgeon: You need to see an orthopaedic surgeon who specializes in hip reconstruction. If surgery is recommended, there are many options available. ...Read more

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On PET scan the phrase "central photopenia suggesting necrosis" what does this mean?

On PET scan the phrase "central photopenia suggesting necrosis" what does this mean?

Usually necrosis: PET scan uses F18 FDG (a glucose metabolite) to localize active metabolic processes such as tumors. The uptake of the radiopharmaceutical is considered hot when increased over normal tissues or background Sometimes central portion of tumor is photogenic or cold reflecting necrosis or death of some tumor. Necrosis can be related to chemotherapy or on presentation when tumor outgrows blood supply ...Read more

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Predinisone for 6 days. 100mg, 90, 70, 60, 60, 40 then done. Was this safe? Am I at risk for adrenal damage or necrosis now?

Totally safe!: Hi. Yes, a prednisone taper such as you describe is 100% safe. Can't say if it was effective, because you don't even tell us what your doc is/was treating. But a taper of those doses over that time is 110% safe. And "adrenal necrosis" is NEVER an issue with a glucocorticoid burst & taper! It's pituitary corticotroph suppression we worry about with prolonged high-dose glucocorticoid therapy. Cheers ...Read more

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Prominent interface hepatic score 4/4 Spotty necrosis score 2/4 Fibrous expation of portal area score 3/6 What would that mean?

Prominent interface hepatic score 4/4
Spotty necrosis score 2/4
Fibrous expation of portal area score 3/6
What would that mean?

GI: Its best you consult a Gastroenterologist to explain this to you. I'm sure a healthtap doctor specializig in GI can be of some assistance. ...Read more

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What is necrosis? Just irrevesible cell then dead off and cause inflammation? Does it mean whenever there is a mild injury, our cell die and necrosis?

What is necrosis? Just irrevesible cell then dead off and cause inflammation? Does it mean whenever there is a mild injury, our cell die and necrosis?

Necrosis: Cell death is said to occur by two alternative, opposite modes: apoptosis, a programmed, managed form of cell death, and necrosis, an unordered and accidental form of cellular dying. ...Read more