Doctor insights on:
Natalizumab Multiple Sclerosis
A disorder causing usually episodic loss of myelin (demyelination) which disrupts function of central nervous system. Can lead to nerve damage because nerve requires myelin to function best. Classically relapsing and remitting or chronic and progressive. The former is characterized by transient neurological episodes of dysfunction separate in time and in space ...Read more
Maybe: Tysabri is a highly effective, once-monthly IV therapy for relapsing forms of ms. It is generally used as a second or third line treatment due to the risk of a rare brain infection. However, depending on how your ms is acting, the risk may well be worth it in order to control your disease. This is a decision between you and your treating neurologist. Discuss concerns with him/her. ...Read moreSee 1 more doctor answer
Can you tell me about having multiple sclerosis and being tested for the jc virus before starting tysabri?
SEQUENCE: Tysabri is most potent MS drug on market, but risk of PML approaches 1 in 90, if 2 yrs of usage, prior chemotherapeutic agents, and positive anti-JCV index test. However, in many others with negative testing, risk is less than 1 in 40,000 at 2 yrs. Positive test does NOT exclude Tysabri, but maybe stop at 18-24 months, and switch to Gilenya at that point. ...Read more
Which treatment would you recommend in multiple sclerosis (suggestions by our neurologist: gylenia, tysabri or fumaric acid - first treatment!)?
None of those: The drugs that i would recommend as a first treatment would either be Rebif or copaxone. These are shots, but they have many years over these meds you mentioned, the are safer than the meds you mentioned and they are likely just as affective. I have been on Rebif for 10 years. ...Read moreSee 1 more doctor answer
Define new...: First line therapies include: -interferon beta-1a (avonex) im once a week. -interferon beta-1a (rebif) sc three times a week. -interferon beta-1b (betaseron, extavia) sc every other day. -glatiramer acetate sc (copaxone) sc daily. Second line therapies include: -mitoxantrone (novantrone) IV q3months. -natalizumab (tysabri) IV q4weeks. -fingolimod (gilenya) PO daily. ...Read moreSee 2 more doctor answers
Might be difficult: In a friend who is being treated and controlled with potent meds, you might think they look completely normal. If undiagnosed, they might display inordinate fatigue, get confused with poor memory, have bad balance, trouble with visual loss, weakness in legs, etc. This is a complex area for most physicians, and an ms specialty focused neurologist is critical. ...Read moreSee 2 more doctor answers
- Talk to a doctor live online for free
- Multiple sclerosis
- High heart rate and multiple sclerosis
- Can multiple sclerosis cause sciatica pains?
- Ask a doctor a question free online
- Primary progressive multiple sclerosis life expectancy
- Multiple sclerosis head pressure
- How does multiple sclerosis spread to other parts of the body?
- Multiple sclerosis and xanax
- Talk to a neurologist online