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Doctor insights on: Natalizumab Multiple Sclerosis

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I was diagnosed with multiple sclerosis and dr wants me on tysabri;what is it?

I was diagnosed with multiple sclerosis and dr wants me on tysabri;what is it?

Tysabri: Tysabri is (natalizumab) injections.It is used to prevent episodes of symptons and slow the worsening of disability in people who have relapsing forms(course of disease where symptoms flare p from time to time)of multiple sclerosis. ...Read more

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Dr. Bennett Machanic
1,384 doctors shared insights

Multiple Sclerosis (Definition)

A disorder causing usually episodic loss of myelin (demyelination) which disrupts function of central nervous system. Can lead to nerve damage because nerve requires myelin to function best. Classically relapsing and remitting or chronic and progressive. The former is characterized by transient neurological episodes of dysfunction separate in time and in space ...Read more


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I have multiple sclerosis, should I take tysabri? For my medication

Maybe: Tysabri is a highly effective, once-monthly IV therapy for relapsing forms of ms. It is generally used as a second or third line treatment due to the risk of a rare brain infection. However, depending on how your ms is acting, the risk may well be worth it in order to control your disease. This is a decision between you and your treating neurologist. Discuss concerns with him/her. ...Read more

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Iis there anyone who has multiple sclerosis and taking tysabri?

Iis there anyone who has multiple sclerosis and taking tysabri?

Tysabri: I dont know the numbers but there are several patients who are taking injections of tysabri. ...Read more

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Can you tell me about having multiple sclerosis and being tested for the jc virus before starting tysabri?

Can you tell me about having multiple sclerosis and being tested for the jc virus before starting tysabri?

SEQUENCE: Tysabri is most potent MS drug on market, but risk of PML approaches 1 in 90, if 2 yrs of usage, prior chemotherapeutic agents, and positive anti-JCV index test. However, in many others with negative testing, risk is less than 1 in 40,000 at 2 yrs. Positive test does NOT exclude Tysabri, but maybe stop at 18-24 months, and switch to Gilenya at that point. ...Read more

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Which treatment would you recommend in multiple sclerosis (suggestions by our neurologist: gylenia, tysabri or fumaric acid - first treatment!)?

Which treatment would you recommend in multiple sclerosis (suggestions by our neurologist: gylenia, tysabri or fumaric acid - first treatment!)?

None of those: The drugs that i would recommend as a first treatment would either be Rebif or copaxone. These are shots, but they have many years over these meds you mentioned, the are safer than the meds you mentioned and they are likely just as affective. I have been on Rebif for 10 years. ...Read more

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What new treatments are there for multiple sclerosis?

What new treatments are there for multiple sclerosis?

Define new...: First line therapies include: -interferon beta-1a (avonex) im once a week. -interferon beta-1a (rebif) sc three times a week. -interferon beta-1b (betaseron, extavia) sc every other day. -glatiramer acetate sc (copaxone) sc daily. Second line therapies include: -mitoxantrone (novantrone) IV q3months. -natalizumab (tysabri) IV q4weeks. -fingolimod (gilenya) PO daily. ...Read more

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Can I catch multiple sclerosis?

No: MS is not an infectious disorder. Instead, there is varying genetic susceptibility triggered by environmental influences. ...Read more

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If I have multiple sclerosis, how can I reduce the effects of an attack?

Get relapse treated: All significant relapses should be treated ASAP. Choices include oral or intravenous steroids, injections of ACTH, plasmapheresis, and if pregnant, IVIG. Better yet, prevent relapses, by using potent MS meds such as Tysabri or Gilenya. ...Read more

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How do I know if someone has multiple sclerosis?

How do I know if someone has multiple sclerosis?

Might be difficult: In a friend who is being treated and controlled with potent meds, you might think they look completely normal. If undiagnosed, they might display inordinate fatigue, get confused with poor memory, have bad balance, trouble with visual loss, weakness in legs, etc. This is a complex area for most physicians, and an ms specialty focused neurologist is critical. ...Read more

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Can you still not be in a wheelchair after having multiple sclerosis for years?

Yes: Some people with MS have a more rapid progression of debilitation while others continue to function with less disability. The medications that are available today have helped manage the symptoms and in some cases slow the progression. ...Read more

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Sclerosis (Definition)

We neurologists employ the term to describe localized damage involving the central nervous system, and sclerosis means scarring. If in many areas, might be multiple sclerosis. If affecting the motor nerve cell, ...Read more