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Neurochemistry 101: Persistent activation of central nervous system nmda receptors by the excitatory Amino Acid glutamate has been hypothesized to contribute to the symptomatology of alzheimer’s disease. Namenda (memantine) is postulated to exert its therapeutic effect through its action by blocking nmda receptors. Namenda (memantine) is approved by the fda for the treatment of moderate to severe alzheimer's dementia. ...Read moreSee 2 more doctor answers
Used for Alzheimer: It's used to treat the symptoms of alzheimer's disease. It works by decreasing abnormal activity in the brain. Can help people with alzheimer's disease to think more clearly and perform daily activities more easily, but it is not a cure and does not stop the progression of the disease. ...Read more
Alzheimer's: Indicated for moderate to severe alzheimer's dementia, and used best in combination with anticholinergic drugs. Seems to slow memory loss, improve behavior, especially agitation, and maybe very useful in nursing homes, where has been noted to improve tv watching. Actually very safe, but only modestly effective. ...Read moreSee 2 more doctor answers
I take Namenda (memantine) 10mg once a day but have not noticed an improvement, just noticed that it has gotten worse. It has been a month, when does it kick in?
Step-by-step: The mfg suggests a weekly step up over a month from once a day 5mg thru twice a day 10mg. So, your dose is only half that. Also, it is intended for Alzheimer's not vascular - so, it might not be the best for you depending on your condition. Your doctor is the best person to discuss this all with. It's follow-up to the prescribing. Best! ...Read moreSee 1 more doctor answer
Dizziness: The main side-effect (3%) compared to placebo in fda trials was dizziness. However a small percentage of demented patients may have varying symptoms including aggressiveness, apathy, depression. Behavioral changes happen within the first few weeks as a rule but are reversible with discontinuation. ...Read more