Top 20 Doctor insights on: Naloxone challenge test
Naloxone in urine: This will depend on the testing method used. I would ask the person ordering the test this question. ...Read more
If being tested SPECIFICALLY for naloxone, meaning only naloxone and nothing else, how long would it or its metabolites be detectable on a lab test?
Half life: Thank you for clarifying. To indirectly answer your question, half life of naloxone is about 1.6 hours. Metabolism is in the liver. 75% of all original product and metabolites will be cleared by 3days and over 90% in a week. The reported sensitivity of the serum test is to less than 1%, so extrapolating about 10 days would be required. ...Read more
Not usually: Naloxone is not screened for in most tests used for that purpose, although in larger amounts it may cross-react with the test for morphine/codeine. If confirmatory testing is done (gas chromatography/mass spectroscopy and others), Naloxone can be specifically identified, if one is looking for it. Did you od and get treated with naloxone? Your doctors need to know that immediately. ...Read more
If Suboxone was taken Friday and Saturday would the naloxone still be in the urine on tuesday? (yes the clinic here test for both ingredients in subs)
Probably: Not. Why not just be honest before you take the test? It's a lot better for trust!! ...Read more
Depends on how given: If given intravenously, it works literally in seconds (10-20 seconds to start working, works fully in couple minutes); if given intramuscularly (im) it takes 2-10 minutes to kick in. If given in a nasal spray (which is being used in several communitites to help addicts and their friends treat od) it works in-between IV and im, starting in 1-2 minutes, and taking full effect by 5-10 minutes. ...Read moreSee 1 more doctor answer
Nifty Naloxone: Naloxone, or Narcan (naloxone) is intended to reverse narcotic overdose and is usually given in the vein, muscle or breathing tube (in emergencies). It has a very rapid onset of action but a short life in the body. It's half life is 64 minutes, which means in approximately 4 hours it is completely out of the body primarily through the kidneys. Diminished kidney function could prolong the drug effect. ...Read moreSee 1 more doctor answer
I have been stable taking Bup/Naloxone 8/2, 1/2 tab 3-4 x day for 8 years for pain, but insurance no longer will pay, is there any other med option?
It is possible: It is possible to be allergic to any medication. A medication has other ingredients, such as stabilizers, preservatives, pH buffers, etc..., and a person may be allergic to one of the other ingredients. Also, a person can be ok with the drug, but react to a breakdown product of the drug, or react to a "bound" combination of the drug+substance (the substance may be from the person's own body). ...Read moreSee 1 more doctor answer