Doctor insights on:
Myoglobin Secondary Structure
Does peripheral edema cause structural damage to the tissue that is swollen? Does increased interstitial fluid break cellular junctions?
Yes and yes: If present for a long time, the first answer is yes and I think the second answer is probably also yes. ...Read more
Muscle growth: Many men desire muscular development and this has been so probably for many thousands of years. As a physician I have seen this done consistently well and healthy through sensible weight training which stimulates muscle development through human growth factor, Testosterone and other natural endogenous substances. Avoid exogenous supplements (such as steroids and probably Mechano ) Go natural! ...Read more
How come the myocardium be replaced by connective tissue rather than muscle tissue if an injury occurs?
Connective tissue: This is the bodies response to cell injury and cell death as muscle does not regenerate. ...Read more
Could undifferentiated connective tissue disease cause pain in muscles such as traps, upper arms etc?
Can complex renal cysts cause inflammation around surrounding tissue? Would that be indicative of cancer?
Why are proximal tubular cells not affected in chronic renal failure and thereby not causing glucosuria?
Good question: Chronic renal disease is most often caused by damage to the blood vessels or the glomeruli / filters, leaving the proximal tubular cells able to work on however much filtrate is present. ...Read more
What can cause high blood levels of myoglobin other than damage to skeletal muscle or heart muscle?
Which pain-causing diseases/disorders cause malfunction in transient receptor potential cation channels of subclass a type (trpa1)? Autoantibodies?
TRPA1 Gene Family: The best article i've read on this gene family is ===> http://www.Genecards.Org/cgi-bin/carddisp.Pl?Gene=trpa1. The clinical significance of mutations in this gene has been related to caffeine and nicotine sensitivity disorders, and rare environmentally-triggered pain disorders. The complete function of this gene family is not known. ...Read more
Kidney failure labs: You would look at the BUN and creatinine (c)levels which would be elevated. C is dependent on the age, sex, race and weight of the patient. You would also expect to see high levels of potassium, phosphorous, and parathyroid hormone in the blood. The carbon dioxide would be low as would be the hemoglobin level. Ask to be sent to a nephrologist for further evaluation and diagnostic studies. ...Read moreSee 1 more doctor answer
What doesthis mean
Small wedge shaped intrinsically t1 hyper intense area adjacent to the falciform ligament likely represents a perfusion abnormality?
What type of tissue is the stroma in your iris? A connective tissue , nervous tissue, or epithelial tissue?
Iris: Stroma is made up of fibers & cells. ...Read more
Can hemolytic anemia cause low blood vol. Thereby causing autonomic dysfunction? Does body see hemolysis as trauma thereby triggering stress hormones?
Whoa: Hemolytic anemia won't affect blood volume but will affect oxygen carrying capacity. Further, if the cause is microangiopathy, lupus, malaria, or any of a variety of others, there may be a huge number of different problems. I'm glad you have an inquiring mind, but there's no need to invoke "stress hormones"; you'd do well to stop reading "pop" explanations if someone's actually seriously sick. ...Read more
In which theory does coarcatation aorta with arch hypoplasia fit in? The hemodynamic or the eptopic ductal tissue theory?
Not truly separate: I don't think that these causation theories are completely separate. Coarctation with arch hypoplasia tends to present with symptoms in the early neonatal period, and coarctation without arch hypoplasia may present later in life, but coarcation without arch hypoplasia is commonly seen in the neonatal period, too. Further discussion is beyond the space limitations here. ...Read more
Not likely.: Most congenital cardiac defects are due to multifactorial inheritance and environmental factors such as Folic Acid deficiency. I am not aware of specific studies linking them to a faulty signal transduction pathway, although such mechanisms frequently become the final common pathway of multiple etiological pathogenic factors. ...Read more