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Doctor insights on: Myeloproliferative Disorders

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Dr. Robert Hawley
186 doctors shared insights

Myeloproliferative Disorders (Overview)

You may consult this site for info on this topic: http://www.umm.edu/health/medical/altmed/condition/myeloproliferative-disorders


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What are the real symptoms of myeloproliferative disorders?

What are the real symptoms of myeloproliferative disorders?

Varaible: There are 3 main types- essential thrombocytosis (et), polycythemia vera (pv) and myelofibrosis (mf). In et, there is increased clotting and risk for strokes. In pv, there is generalized itchiness, ruddy face, and stroke risk. In mf, patients get low blood counts over time causing fatigue, large spleen, poor appetite, abdomen pain, transfusion need. ...Read more

Dr. Robert Hawley
186 doctors shared insights

Myeloproliferative Disorders (Overview)

You may consult this site for info on this topic: http://www.umm.edu/health/medical/altmed/condition/myeloproliferative-disorders


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How do you know who is most likely to get myeloproliferative disorders?

How do you know who is most likely to get myeloproliferative disorders?

Not able to know: We do not know who is most likely to develop a myeloproliferative disorder. It is, however, a disease that increases in incidence with age. ...Read more

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Dr. Miroslava Fox Dr. Fox
<b>1</b> doctor agreed:
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Living with Manic Depressive Disorder (Checklist)

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Are there any treatments for acute transformation of overlap myelodysplascity/myeloproliferative disorder in an elderly patient If so, what are they?

Are there  any treatments for acute transformation of overlap myelodysplascity/myeloproliferative disorder in an elderly patient  If so, what are they?

Try hypomethylating: CMML is common form of overlap syndrome, can be treated with hypomethylating agent (VADAZA) as MDS. Efficay? If acute transformation to acute leukemia (AML), then should treat leukemia. If pt is older and not a candidate for intense induction, hypomethylating is also an option. For other acute transformation, treat them accordingly. Sometime, just supportive care or clinical trial consideration. ...Read more

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What are the real symptoms of myeloproliferative disorders?

Varaible: There are 3 main types- essential thrombocytosis (et), polycythemia vera (pv) and myelofibrosis (mf). In et, there is increased clotting and risk for strokes. In pv, there is generalized itchiness, ruddy face, and stroke risk. In mf, patients get low blood counts over time causing fatigue, large spleen, poor appetite, abdomen pain, transfusion need. ...Read more

Dr. Barbara Lavi Dr. Lavi
<b>1</b> doctor agreed:
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How do you know who is most likely to get myeloproliferative disorders?

Not able to know: We do not know who is most likely to develop a myeloproliferative disorder. It is, however, a disease that increases in incidence with age. ...Read more

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What is the definition or description of: Myeloproliferative disorders?

See below: You may consult this site for info on this topic: http://www.umm.edu/health/medical/altmed/condition/myeloproliferative-disorders ...Read more

Dr. Adam Lewis Dr. Lewis
<b>3</b> doctors agreed:
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Living with Borderline Personality Disorder (Checklist)

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Can myeloproliferative disorder be diagnosed by an mri?

Can myeloproliferative disorder be diagnosed by an mri?

Myeloid and: Lymphoid refer to blood and marrow elements. Mri cannot greatly help, but can show marrow signal abnormalities. A bone marrow follows evaluation of a smear to discern type and yes no to leukemia, imaging not in the line up unless symptom point to a bone, . ...Read more

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What blood tests would indicate a Myeloproliferative disorder?

What blood tests would indicate a Myeloproliferative disorder?

Abnormal(high) blood: This disorder is suspected in individuals who have a very high WBC count(Like in CML) and also has a genetic abnormality(Philadelphia Chromosome present). Other patients have Myelofibrosis where there is a very big enlargement of the spleen. Occasionally it is just very platelet count(Essential Thrombocythemia(ET) ...Read more

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What is the prognostic significance of a jak2 mutation in a person without the defining criteria for a myeloproliferative disorder ?

What is the prognostic significance of a jak2 mutation in a person without the defining criteria for a myeloproliferative disorder ?

Need close follow-up: The specificity of the jak2 v617f pcr test for the diagnosis of myelpproliferative disorder is very high, near 100%. After excluding sample mix-up, any patient with a positive jak2 mutation should be carefully followed for the development of polycythemia vera, myelofibrosis, or essential throbocythemia. ...Read more

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Treating Obsessive Compulsive Disorder (Checklist)

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What does myeloproliferative disorder with essential thrombocythemia mean?

What does  myeloproliferative disorder with essential thrombocythemia mean?

Too many platelets: The myeloproliferative neoplasms (mpns) involve terminal myeloid cell expansion in the peripheral blood, resulting in various combinations of erythrocytosis (rbc's), leukocytosis (wbc's), thrombocytosis (platelets), bone marrow hypercellularity/fibrosis, and splenomegaly (enlarged spleen). Essential thrombocythemia is a diagnosis of exclusion, made when other forms of mpn are ruled out. ...Read more

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What is a myeloproliferative disorder that includes essential thrombocythemia?

What is a myeloproliferative disorder that includes essential thrombocythemia?

Too many platelets: Myeloproliferative disorders are a set of marrow malignancies characterized by excessive production of certain types of blood cells. Essential thrombocytopenia is one of them, in which marrow makes too many platelets. There are well-tolerated oral agents which help. Other myelodysplastic syndromes are polycythemia vera and chronic myelogenous leukemia. ...Read more

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Is overlap myelodysplasticity myeloproliferative disorder a name for one disorder with common features of two disorders or the one blood disorder ?

Is overlap myelodysplasticity myeloproliferative disorder a name for one disorder with common features of two disorders or the one blood disorder ?

Spectrum of disease : Myelodyaplastic syndrome is a type of myeloproliferative disorder. So it's one disease but there is a spectrum. Myelodyaplasia means abnormal looking blood cells seen in your blood or in the bone marrow. This is usually due to an underlying bone marrow issue like infection or a possible bone marrow cancer and a bone marrow biopsy could be warranted at this point. Talk to your doctor . Take care. ...Read more

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If a 91 year old has an acute transformation of his myeloproliferative disorder & is treated then would the treatment normally be given an in ICU?

If a 91 year old has an acute transformation of his myeloproliferative disorder & is treated then would the treatment normally be given an in ICU?

Depends: Doctors usually recommend treatment based on the patients needs. ICU ensures close monitoring and fast response to any sign of major complication. For a 91 y/o it depends on his overall health status, prognosis and the extent of treatment elected by patient or his proxy. ...Read more