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Doctor insights on: Myelofibrosis Treatment

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I have myelofibrosis and complication of hardening of connective tissues. Is there a treatment for this complication ?

I have myelofibrosis and complication of hardening of connective tissues. Is there a treatment for this complication ?

Maybe.: Myelofibrosis is a unusual disease of blood and bone marrow where the marrow is replaced by what looks like scar tissue. This results in bone marrow cells moving to the liver and spleen, those organs enlarge and become hard. There is one drug, jakafi, (ruxolitinib) fda approved to shrink the spleen. There are other drugs like it in trial. Only cure is bone marrow transplant, but there are significant risks. ...Read more

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My sister is diagnostic to myelofibrosis. Which treatments would be more curable?

My sister is diagnostic to myelofibrosis. Which treatments would be more curable?

Primary myelofibrosi: Allogeneic bone marrow transplantation would be the only curative option for myelofibrosis. Other treatment like jak 2 inhibitor, immunomodulator agent, steroids, etc are only for symptom relief/ palliative therapy. ...Read more

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What is treatment for fibrosis of marrow, and what are chances of survival?

The prognosis in: Myelofibrosis can be quite variable. There is a scoring system which would be of help in an individual case. Talk to your doc about the specifics of your case. ...Read more

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Is there a complete cure for myelofibrosis?

Is there a complete cure for myelofibrosis?

Transplant: The only potential cure for myelofibrosis is an allogeneic stem cell transplant. This requires a stem cell donor and cannot be done with the patient's own stem cells. ...Read more

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Is myelofibrosis. Hereditary?

Is myelofibrosis. Hereditary?

Almost never: Common myelofibrosis and its cousin myeloid metaplasia are almost always sporadic. There are a few genetic marrow-failure syndromes but these are fairly easy to recognize. ...Read more

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What is prognosis for myelofibrosis?

What is prognosis for myelofibrosis?

Depends: They are several phases of the disease and it depends on how much fibrosis is present in the marrow. Since this is included in the group of disorders known as myeloproliferative neoplasms, it can develop into a leukemia. Hope this was helpful. ...Read more

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What cancer would cause myelofibrosis in a 57 year old woman?

What cancer would cause myelofibrosis in a 57 year old woman?

It is a disease: Myelofibrosis is a type of cancer itself although initially it may not show Cancer cells initially. Most such patients develop Leukemia after a period of one to two years. Go see a hematologist if you need further help ...Read more

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Do you know which cancer would cause myelofibrosis in a 57 year old woman?

Do you know which cancer would cause myelofibrosis in a 57 year old woman?

Unknown: The known forms of bone marrow cancer do not cause myelofibrosis Rather Myelofibrosis is a rare form of cancer of the bone marrow itself where the marrow is replaced by scar tissue and is not able to make healthy blood cells. It is considered to be a form of chronic leukemia and represent a group of blood disorders called myeloproliferative disorders . ...Read more

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I've been diagnosed with myelofibrosis after many years looking for a cause to my poor health. Will i ever be cured? Is it a cancer, i've read both.

I've been diagnosed with myelofibrosis after many years looking for a cause to my poor health. Will i ever be cured? Is it a cancer, i've read both.

Not cancer: It is a mutation in a protein jak2 that causes scar tissue in the bonemarrow where you don't make enough red cells. There are more treatments coming but now most treatment is aimed at your symptoms . At this point there is no cure. ...Read more

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My haemotologist told me I have around 5 years before I die from myelofibrosis. What can I expect? Am already in wheelchair as I fafaint when walking.

My haemotologist told me I have around 5 years before I die from myelofibrosis. What can I expect? Am already in wheelchair as I fafaint when walking.

None of us truly: knows when we will die but you have some information from your doc. Many will die before you so please make the very best to the time you have. Try to use your suffering to help others somehow, perhaps on line. Peace and good health. ...Read more