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I have myelofibrosis. How does the disease progress? Does your marrow just keep becoming scar tissue that can't produce blood? Is bone pain common?
Possibly: This would not be an early sign of this problem. As you know, this condition can cause an anemia and this could cause your heart to beat faster, but your would have to be very anemic to experience palpitations. If you are concerned get it check out by your doctor. ...Read moreSee 1 more doctor answer
Not initially: Myelofibrosis is a disease of the bone marrow which causes increasing fibrosis (scarring) over time and loss of the marrow to function normally. Thus until the marrow is harmed to the degree where you develop anemia or low platelets or low white blood cells you will normally not experience any symptoms. ...Read moreSee 1 more doctor answer
I've been diagnosed with myelofibrosis after many years looking for a cause to my poor health. Will i ever be cured? Is it a cancer, i've read both.
Unknown: The known forms of bone marrow cancer do not cause myelofibrosis Rather Myelofibrosis is a rare form of cancer of the bone marrow itself where the marrow is replaced by scar tissue and is not able to make healthy blood cells. It is considered to be a form of chronic leukemia and represent a group of blood disorders called myeloproliferative disorders . ...Read more
Multiple options: Depending on symptoms, options include transfusions, drugs to stimulate red cell production (erythropoietin, androgens), thalidomide derivatives (lenolidomide, pomalidomide), jak2 inhibitors (jakafi), splenectomy, radiation therapy, chemotherapy (hydroxyurea) or bone marrow transplant. ...Read more
I have myelofibrosis and complication of hardening of connective tissues. Is there a treatment for this complication ?
Maybe.: Myelofibrosis is a unusual disease of blood and bone marrow where the marrow is replaced by what looks like scar tissue. This results in bone marrow cells moving to the liver and spleen, those organs enlarge and become hard. There is one drug, jakafi, (ruxolitinib) fda approved to shrink the spleen. There are other drugs like it in trial. Only cure is bone marrow transplant, but there are significant risks. ...Read more
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