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Doctor insights on: Myelodysplastic Syndrome

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What are the symptoms of myelodysplastic syndromes (mds)?

What are the symptoms of myelodysplastic syndromes (mds)?

It varies: There may be none or the patient may feel tired from anemia, show signs of bruising from low platelets or infections from low white blood counts. ...Read more

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Dr. Aurea Tomeski
42 doctors shared insights

Pre Leukemia (Myelodysplastic Syndrome) (Definition)

Myelodysplastic syndrome (MDS) is a bone marrow disorder which causes low blood counts (anemia and low white cells and platelets) and a tendendency to develop leukemia. There are several different forms of MDS and many different types of treatment. Hematologists and oncologists specialize in treating this condition. The diagnosis is made by performing a bone marrow biopsy. ...Read more


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What are the tests for myelodysplastic syndromes?

Bone marrow: The only way to diagnose a myelodysplastic syndrome completely and accurately including prognostic factors is by performing a bone marrow biopsy and aspiration with subsequent multi-pronged assessment: morphology, flow cytometry, cytogenetics, and molecular studies. Some changes in the peripheral blood may suggest mds but a complete diagnosis still relies on bone marrow examination. ...Read more

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What are effective treatments for myelodysplastic syndromes (mds)?

What are effective treatments for myelodysplastic syndromes (mds)?

Treatment options: As mentioned it depends on the clinical situation. Sometimes treatment is just with observation, transfusions when needed. Drugs called growth factors can be used in some situations. There are some chemotherapy drugs that are effective and for aggressive cases a stem cell transplant can be used. ...Read more

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What are the symptoms of myelodysplastic syndromes (mds)?

It varies: There may be none or the patient may feel tired from anemia, show signs of bruising from low platelets or infections from low white blood counts. ...Read more

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My husbands mother wad diagnosed with myelodysplastic syndrome in her mid 50's , passed away she was deficient of chromosome 8. Is this hereditary?

My husbands mother wad diagnosed with myelodysplastic syndrome in her mid 50's , passed away  she was  deficient of chromosome 8. Is this hereditary?

Probably not: Even though a history of mds in first degree relatives may slightly increase the overall risk to develop mds, the risk is still minimal and these diseases are usually not hereditary. ...Read more

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What are the tests for myelodysplastic syndromes?

Bone marrow: The only way to diagnose a myelodysplastic syndrome completely and accurately including prognostic factors is by performing a bone marrow biopsy and aspiration with subsequent multi-pronged assessment: morphology, flow cytometry, cytogenetics, and molecular studies. Some changes in the peripheral blood may suggest mds but a complete diagnosis still relies on bone marrow examination. ...Read more

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If myelodysplastic syndrome is mainly caused by exposure to certain elements. How long ago would that exposure have been ?

If myelodysplastic syndrome is mainly caused by exposure to certain elements. How long ago would that exposure  have been ?

MDS Carcinogens: Alkylating chemotherapies can cause MDS 5-7 years from last dose. Radiation can cause MDS 10-40 years after last dose. Although it's debatable whether modern radiation therapy can cause MDS (see my PubMed article: 24577814). Benzene can cause bone marrow aplasia, MDS or AML 4-14 years after exposure. Tobacco (benzene et al) smoking is significantly associated with MDS with onset 10-20 years. ...Read more

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I have mgus and myelodysplastic syndrome and my dr is not treating me should I change drs?

See below...: Both monoclonal gammopathy of undetermined significance (mgus) and myelodysplastic syndrome (mds) are disease entities that may be managed by watchful waiting. If your physician is a hematologist/oncologist then he or she probably has significant experience with these diseases and manages them accordingly. ...Read more

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What is the treatment for myelodysplastic syndrome?

See below...: Myelodysplastic syndromes (mds) represent a group of bone marrow cancers similar to leukemias in many respects but usually with a less aggressive evolution. Like many other types of cancer, treatment includes chemotherapy and sometimes bone marrow transplantation; however, if the mds is low grade sometimes treatment is not necessary, at least not initially (watchful waiting). ...Read more

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