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Doctor insights on: Mycobacterium Tuberculosis Mechanism Of Infection

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Dr. Gurmukh Singh Dr. Singh
Pathology
45 years in practice
University of Pune, Armed Forces Medical College
1

1
Do people with mycobacterium tuberculosis infection have a lot of pain?

Do people with mycobacterium tuberculosis infection have a lot of pain?

Usually not: Mycobacterial tuberculosis infection can affect any part of the body and depending on the organ affected may have dull pain especially if skin and/or bone are involved. In vast majority of patients with TB pain is not a dominant symptom.

Dr. Scott Lindquist
609 Doctors shared insights

Mycobacterium Tuberculosis Infection (Definition)

Mycobacterium tuberculosis is an infectious organism that spreads by droplets coughed out by an infected person. Infection is established initially in lungs, but can spread within lungs & to other body parts, or can become latent, with reactivation occurring years to decades later. With effective treatment, it can be completely eliminated although drug resistant ...Read more


Dr. Gurmukh Singh Dr. Singh
Pathology
45 years in practice
University of Pune, Armed Forces Medical College
2

2
How common is it for somebody to get mycobacterium tuberculosis infection?

How common is it for somebody to get mycobacterium tuberculosis infection?

Common: World wide TB is an endemic illness affecting millions of people. In the US, TB is some times seen in immigrants from poor countries. It is also associated with immune deficiency, including AIDS.

Dr. Lokesh Guglani Dr. Guglani
Pediatrics - Pulmonology
17 years in practice
University of Arkansas for Medical Sciences/UAMS College of Medicine
3

3
What is the definition or description of: mycobacterium tuberculosis infection?

What is the definition or description of: mycobacterium tuberculosis infection?

Chronic infection: Mycobacterium tuberculosis is an infectious organism that spreads by droplets coughed out by an infected person. Infection is established initially in lungs, but can spread within lungs & to other body parts, or can become latent, with reactivation occurring years to decades later. With effective treatment, it can be completely eliminated although drug resistant strains are becoming common.

Dr. Douglas Arenberg Dr. Arenberg
Internal Medicine - Pulmonary Critical Care
27 years in practice
University of Illinois College of Medicine
4

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Which treatment works the best and fastest for mycobacterium tuberculosis infection?

Which treatment works the best and fastest for mycobacterium tuberculosis infection?

For TB: Treatment is empiric at first, most commonly using four drugs to avoid the development of resistant organisms. After testing of the bug (which can take 8 weeks), treatment can be narrowed to two drugs to which it is susceptible, but continued for a total of 6 months (at least). Treatment of TB works best when it is administered under direct supervision of a qualified public health official.

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Dr. Carlo Hatem Dr. Hatem
Internal Medicine - Pulmonary Critical Care
21 years in practice
American University of Beirut Faculty of Medicine
5

5
Will mycobacterium tuberculosis infection kill me if I don't get treatment?

Will mycobacterium tuberculosis infection kill me if I don't get treatment?

Yes: And you will hurt everyone you love and live with by infecting them as well. In many countries you don't get to decide. You either take the treatment voluntarily or you get detained and kept in isolation. This applies to open tuberculosis. If you have latent tuberculosis, it's a different story. Chances of death from latent TB are almost zero, unless it turns into the open form.

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David Miller Dr. Miller
Family Medicine
6 years in practice
Pacific Northwest University of Health Sciences
6

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What's the best treatment to get rid of mycobacterium tuberculosis infection?

What's the best treatment to get rid of mycobacterium tuberculosis infection?

Multi-drug therapy: Mycobacterium tuberculosis is the bacterium that causes tuberculosis. This was the among the most common causes of lung disease in the early 20th century when it was called "consumption." Nowadays it is unusual in the US but still common in the 3rd world and very serious. Treatment is a regimen of 2 to 4 drugs for many months. Resistant strains are cropping up, which complicates matters greatly.

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Dr. Ed Friedlander Dr. Friedlander
Pathology
40 years in practice
Northwestern University Feinberg School of Medicine
7

7
How can I culture mycobacterium tuberculosis?

You don't: The lab does, on special media. If you try it yourself, and you actually have somebody with active TB to grow it from, you'll generate a mass of nasty bacteria and if you don't know exactly what you are doing, you can make everybody around you very sick.

Dr. Larry Lutwick Dr. Lutwick
Internal Medicine - Infectious Disease
45 years in practice
George Washington University Medical School
8

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What is the pathophysiology of mycobacterium tuberculosis?

What is the pathophysiology of mycobacterium tuberculosis?

Complex: Mtb is acquired thru respiratory route and replicates in the lung before asymptomatically disseminates to other organs. After about 6-8 weeks, the immune system starts to respond to the bug, walling the bacilli off in granulomas. Other than a positive skin test, 90% of people stay well. Of the rest, half will "reactivate" within 2 yrs and the others later sometimes due to immune suppression.

Dr. Larry Lutwick Dr. Lutwick
Internal Medicine - Infectious Disease
45 years in practice
George Washington University Medical School
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Dr. Larry Lutwick Dr. Lutwick
Internal Medicine - Infectious Disease
45 years in practice
George Washington University Medical School
10

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What are the symptoms of mycobacterium tuberculosis?

What are the symptoms of mycobacterium tuberculosis?

Depends on where: But the most common site for tuberculosis is the lung and symptoms include fever, cough, night sweats and weight loss.

Dr. Lori Lange Dr. Lange
Family Medicine
years in practice
Philadelphia College of Osteopathic Medicine
11

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How does mycobacterium tuberculosis attack and spread?

Tb Infection: How does mycobacterium tuberculosis attack and spread? Usually by droplet transmission through the air. Cough, fatigue and being in an area with Tb carriers or in a high risk environment where you come in contact with infected people.

Dr. Michael Ein Dr. Ein
Internal Medicine - Infectious Disease
44 years in practice
McGill University Faculty of Medicine
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What could be the reason why mycobacterium tuberculosis is resistant to many biocides?

It's complicated: Tb needs to be treated with several drugs to which it is susceptable at the same time to prevent the emergence of mutational resistance. It also needs to be treated for at least 6 months. In many 3rd world countries TB meds can be purchased over the counter and people take them incorrectly and not long enough. In usa some pts are non compliant with treatment. Both these cause resistance.

Dr. Kathleen Mullane Dr. Mullane
Internal Medicine
28 years in practice
Midwestern University Chicago College of Osteopathic Medicine
13

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How is it that cord factor antigen aid in the diagnosis of mycobacterium tuberculosis?

Not for prime time: Cord factor is a molecule that enhances virulence of mtb. Usually the non-tuberculous mycobacterium don't have it so it can be used to differentiate between the infections. Why? Mtb is considered contagious & non-tb mycobacterium are not frequently so. Experimentally this factor has been looked at as a quick test to differentiate between the 2 types of infection. Not yet commercially available.

Dr. H. Hunter Handsfield Dr. Handsfield
Internal Medicine - Infectious Disease
49 years in practice
Columbia University College of Physicians and Surgeons
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What is Pcr test from menstrual blood for mycobacterium tuberculosis complex.

Test for genital TB: This is a test to see if you have genital tract tuberculosis, i.e. TB of the uterus, fallopian tubes, etc.

Dr. Klaus d Lessnau Dr. Lessnau
Internal Medicine - Pulmonary Critical Care
32 years in practice
Friedrich-Alexander University of Erlangen-Nurnberg
15

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What is mycobacterium tuberculosis complex? My endometrium biopsy report says this.

Clarify with doc: It is either mycobacterium tuberculosis or mycobacterium avium or something else. Probably the lab is working on it. Clarify with your doc although the final result may take a few more days.

Dr. Larry Lutwick Dr. Lutwick
Internal Medicine - Infectious Disease
45 years in practice
George Washington University Medical School
16
Dr. C. michael Bowman Dr. Bowman
Pediatrics
42 years in practice
University of Wisconsin School of Medicine and Public Health
17

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Is "mycobacterium tuberculosis " can cause kyphosis or scoliosis directly (without affecting the lungs)?!

Is "mycobacterium tuberculosis " can cause kyphosis or scoliosis directly (without affecting the lungs)?!

Yes: It is possible to get tuberculosis of the spine which can cause significant damage and deformity. However, it usually has pain along with the infection. The TB germs may enter the body through the lungs but then be controlled there but circulate and cause their major damage outside the lungs sometime later.

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Dr. Hushang Haghighat Dr. Haghighat
Pediatrics - Hematology & Oncology
years in practice
18

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Age 65, NHL in remission, Persistent cough. Sputum culture: Mycobacterium other than tuberculosis. Place suggest next steps.

Age 65, NHL in remission, Persistent cough. Sputum culture: Mycobacterium other than tuberculosis. Place suggest next steps.

Antibiotic: If culture positive for mycobacterium you should be treated with antibiotic and have chest Xray and follow up.

Dr. Nayana Trivedi Dr. Trivedi
Internal Medicine
35 years in practice
South Gujarat University, Government Medical College
19
Dr. Dennis Clifford Dr. Clifford
Internal Medicine - Pulmonary Critical Care
39 years in practice
University of Minnesota Medical School
20

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How can non-toxic bacteria such as mycobacterium tuberculosis cause pulmonary fibrosis?

How can non-toxic bacteria such as mycobacterium tuberculosis cause pulmonary fibrosis?

Inflammation: Tb is an infection which can cause an inflammatory reaction and scar tissue can be the result of that process.

Dr. Qamar Khan
9 Doctors shared insights

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Dr. Klaus d Lessnau
1,207 Doctors shared insights

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