Doctor insights on:
Mycobacterium Chelonae Treatment
Complex: M. Avium- intracellulare (mac) infections can result in lung and other organ damage, depending on the severity of immunodeficiency. In people with an intact immune system, mac infection is a slow process and can take years before therapy is initiated (2 or 3 antibiotics- e.g. Ethambutol, cipro, (ciprofloxacin) and rifabutin). Therapy can last a minimum of 12 months if a lung infection is involved. ...Read moreSee 1 more doctor answer
For TB: Treatment is empiric at first, most commonly using four drugs to avoid the development of resistant organisms. After testing of the bug (which can take 8 weeks), treatment can be narrowed to two drugs to which it is susceptible, but continued for a total of 6 months (at least). Treatment of TB works best when it is administered under direct supervision of a qualified public health official. ...Read moreSee 1 more doctor answer
And you will hurt everyone you love and live with by infecting them as well. In many countries you don't get to decide. You either take the treatment voluntarily or you get detained and kept in isolation.
This applies to open tuberculosis. If you have latent tuberculosis, it's a different story. Chances of death from latent TB are almost zero, unless it turns into the open form. ...Read more
Multi-drug therapy: Mycobacterium tuberculosis is the bacterium that causes tuberculosis. This was the among the most common causes of lung disease in the early 20th century when it was called "consumption." Nowadays it is unusual in the US but still common in the 3rd world and very serious. Treatment is a regimen of 2 to 4 drugs for many months. Resistant strains are cropping up, which complicates matters greatly. ...Read moreSee 1 more doctor answer
Many mycobacteria: There are >200 species of mycobacteria. We worry about mycobacterium tuberculosis because it can be transmitted between people. Atypical mycobacterium, like mai, are not contageous. These are in our h2o supply ; we drink/inhale them. Most are problematic in people w/lung diseases (copd/cystic fibrosis) or those who are immunocompromised (hiv/transplant patients). In normal hosts usually no worry. ...Read more
Complex: Mtb is acquired thru respiratory route and replicates in the lung before asymptomatically disseminates to other organs. After about 6-8 weeks, the immune system starts to respond to the bug, walling the bacilli off in granulomas. Other than a positive skin test, 90% of people stay well. Of the rest, half will "reactivate" within 2 yrs and the others later sometimes due to immune suppression. ...Read more
Chronic infection: Mycobacterium tuberculosis is an infectious organism that spreads by droplets coughed out by an infected person. Infection is established initially in lungs, but can spread within lungs & to other body parts, or can become latent, with reactivation occurring years to decades later. With effective treatment, it can be completely eliminated although drug resistant strains are becoming common. ...Read more
It's complicated: Tb needs to be treated with several drugs to which it is susceptable at the same time to prevent the emergence of mutational resistance. It also needs to be treated for at least 6 months. In many 3rd world countries TB meds can be purchased over the counter and people take them incorrectly and not long enough. In usa some pts are non compliant with treatment. Both these cause resistance. ...Read more
Not for prime time: Cord factor is a molecule that enhances virulence of mtb. Usually the non-tuberculous mycobacterium don't have it so it can be used to differentiate between the infections. Why? Mtb is considered contagious & non-tb mycobacterium are not frequently so. Experimentally this factor has been looked at as a quick test to differentiate between the 2 types of infection. Not yet commercially available. ...Read more
I have been in contact with laboratory-grown specimens of Mycobacterium phlei. I would like to know the symptoms just in case of. Thank you.
Mycobacteria are unlikely to infect you thus symptoms "just in case" are impossible to predict!
Hope this is helpful
Dr Z ...Read more