Doctor insights on:
Myasthenia Gravis Remission
Unknown: In most cases, myasthenia gravis is not inherited and occurs in people with no history of the disorder in their family. About 3 to 5 percent of affected individuals have other family members with myasthenia gravis or other autoimmune disorders, but the inheritance pattern is unknown. For more info please review the following: http://www.Myasthenia.Org/whatismg/faqs.Aspx. ...Read more
Activate muscle: Myasthenia disrupts the connection between nerve and muscle by reducing the number of receptors for a transmitter called acetylcholine. Mestinon (pyridostigmine) prevents acetylcholine from being broken down in the body, giving it more time to diffuse along the muscle and activate the remaining receptors. The net result is to restore effective transmission between nerve and muscle. ...Read moreSee 1 more doctor answer
Myasthenia gravis is a serious autoimmune disorderthis help alleviate symptoms of myasthenia gravis?
See neurologist : Please make sure that you have the proper diagnosis for myasthenia gravis. You will need blood tests for antibodies, and repetitive stimulation studies or even single fiber emg. You must be taken care of by a neurologist who can give you medicines to help with the disease if you to prove to have myasthenia gravis. ...Read more
Wide range of people: Conditions that increase your risk for developing myasthenia include: autoimmune disease (thyroid disease, lupus, rheumatoid, type i diabetes), a tumor called a thymoma, and exposure to certain medications (most famously an immunosuppressant and chelating agent called penicillamine). ...Read more
Fatigable weakness: Myasthenia gravis is an autoimmune disease that disrupts the neuromuscular junction, so that when motor nerves fire the muscle fibers do not reliably contract. It manifests as a "fatigable weakness" (one that gets worse with sustained effort) that can involve the limbs, the cranial nerves (hoarseness, double vision, difficulty swallowing), or, in some dangerous cases, muscles of breathing. ...Read moreSee 2 more doctor answers
Usually very serious: Myasthenia gravis is typically seen in the young and the elderly. In the latter group, they typically have ocular mg, that is there symptoms are confined to the eye muscles. In the young, symptoms include muscle weakness, breathing difficulties, swallowing difficulties, visual problems(double vision, droopy eye lids), problems chewing. Symptoms worsen during the day.If not treated, it can be fatal. ...Read moreSee 2 more doctor answers
Removing a source: In select patients, a thymectomy may lead to a significant reduction in symptoms by removing the organ responsible for producing antibodies responsible for initiating symptoms. This works better in patients who have had some response to medical therapy, and who have an enlarged thymus gland, but this is not absolute. Before choosing this option, you should discuss this with your treating doctor. ...Read moreSee 2 more doctor answers
Yes: Several approaches to Myasthenia Gravis are used to control the immune problems at the Neuromuscular junction, and steroids have proven to be very helpful. Other approaches such as thymectomy or use of Mestinon (pyridostigmine) could be initial interventions. Complex disease that should be handled by skilled neurologist who focuses on neuromuscular areas. ...Read more
Nerve disease: In patients with myasthenia, the acetylcholine receptor that helps form the neuromuscular junction is destroyed by the immune system. This causes nerves to be unable to trigger muscle contraction, leading to fatigable weakness. In demyelinationg disease, the myelin insulation surrounding the nerve is attacked by the immune system, disrupting signal transmission. ...Read more
Women>men: Before the age of 40 mg is 3x more common in women, but at older ages both sexes are equally affected. Familial cases are rare. Congenital mg in children are rarely encountered. Their mothers are asymptomatic, and the condition is often familial. Limb weakness is present but eye movement weakness is the dominant sign. There are also neonatal forms characterized by weak suck, and juvenile forms. ...Read moreSee 1 more doctor answer
NO, NOT AT ALL: Mestinon (pyridostigmine) enhances neuromuscular junctional efficiency by enhancing acetylcholine persistence, but is NOT an immune agent like a steroid. The standard testing for myasthenia gravis looks at antibody reactions, and would be positive or negative irregardless of use of Mestinon (pyridostigmine). ...Read more
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