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Doctor insights on: Myasthenia Gravis Autoimmune Diseases

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Dr. Tracy Lovell
492 doctors shared insights

Autoimmune Disease (Definition)

In auto immune disease the enemy is from with in . As name implies "auto" is self and "immune " is immune system . One 's own immune system for unknown reason turns against self and destroys or damages tissues or cells . List of auto immune disease are many and growing . End result is destruction of of tissues such as thyroid , pancreas or cells such as white ...Read more


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Since myasthenia gravis is a systemic autoimmune disease, why does it often present with asymmetrical ptosis (instead of bilateral)?

Since myasthenia gravis is a systemic autoimmune disease, why does it often present with asymmetrical ptosis (instead of bilateral)?

Fluctuating weakness: Myasthenia is a neuromuscular disease characterized by fluctuating weakness, not all muscles are affected at the same time or to similar degrees. ...Read more

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What does it mean to have the autoimmune disease called myasthenia gravis?

What does it mean to have the autoimmune disease called myasthenia gravis?

Muscle weakness: It causes muscle weakness. It is autoimmune because it has antibodies to your own body, in this case they react with acetylcholine receptors at the neuromuscular junction. Thus the muscles do not get the stimulation to help them function due to the decreased availability of acetylcholine. It is treated with acetylcholinesterase inhibitors that interfer with the the breakdown of acetylcholine. ...Read more

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Myasthenia gravis is a serious autoimmune disorder in which the body produces antibodies to what?

Ach receptor: Mg is a condition in which the body makes antibodies to the muscle receptor for acetyl choline which is the neurotransmitter chemical involved in the transmission of nerve impulses to muscle contraction. These antibodies prevent efficient nerve transmission to muscle and result in weakness and easy fatigue of muscles. ...Read more

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How safe is alloderm for people suffering from auto-immune diseases? I am suffering from myasthenia gravis for a long time now. I am on a moderate dose of corticosteroids for my condition. I know that they suppress the immune system and also slow down hea

How safe is alloderm for people suffering from auto-immune diseases? I am suffering from myasthenia gravis for a long time now. I am on a moderate dose of corticosteroids for my condition. I know that they suppress the immune system and also slow down hea

Alloderm : Alloderm is a processed human skin graft which results in an acellular dermal matrix which can be used for a variety of purposes, including treatment of wounds, reconstructive surgery and hernia repairs. Unlike allograft skin grafts (i.e. Skin from another human), which are eventually rejected, the proprietary processing technique retains the normal collagen bundling and intact basement membrane complex of skin, but without the components (skin and connective tissue cells) that cause an immune reaction. In one study (wainwright dj: use of an acellular allograft dermal matrix (alloderm) in the management of full-thickness burns. Burns. 1995 jun;21(4):243-8) alloderm was used in burn patients and the patients did not demonstrate a specific immune response, either by histology or immunologically. In addition, in your case, the use of corticosteroids would blunt any immune reaction, minimizing the possibility of an immune reaction. This would howver, slow down the healing process, due to the effect of corticosteroids on wound healing. ...Read more

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Myasthenia gravis is a serious autoimmune disorderthis help alleviate symptoms of myasthenia gravis?

See neurologist : Please make sure that you have the proper diagnosis for myasthenia gravis. You will need blood tests for antibodies, and repetitive stimulation studies or even single fiber emg. You must be taken care of by a neurologist who can give you medicines to help with the disease if you to prove to have myasthenia gravis. ...Read more

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How safe is it to have a baby if I have myasthenia gravis? I know people do it, but what are the risks? Both to me and the baby? Will I have to go off my meds? Will i pass the disease on to my baby? I’d really like to have a baby, but i’m worried. My doc

How safe is it to have a baby if I have myasthenia gravis? I know people do it, but what are the risks? Both to me and the baby?  Will I have to go off my meds? Will i pass the disease on to my baby? I’d really like to have a baby, but i’m worried. My doc

The : The more common kind of myasthenia gravis is an acquired condition: your body is tricked into making antibodies that attack its own acetylcholine receptors on the surface of your muscles, reducing the ability of your nerves to activate them, and leading to weakness. There is another, much rarer type of myasthenia gravis that is not acquired, but genetic. Women with acquired myasthenia gravis won't pass the disease itself on to their children, but since the myasthnia antibodies made by mom can cross the placenta into the circulation of the fetus, the fetus can be affected temporarily (mom's antibodies can stay in the baby up to several weeks after birth). This condition is called neonatal myasthenia gravis. Newborns with neonatal myasthenia can have temporary weakness of limb muscles, breathing muscles, and feeding muscles. They can also have a condition called arthrogryposis, stiff joints with limited range of flexibility because they didn't move as much in the womb as they might have otherwise. This is why it is important to have acquired myasthenia gravis well-controlled throughout pregnancy. There are many different kinds of medications used to control myasthenia. Some of them, particularly the immunosuppressants (like methotrexate, azathioprine, mycophenolate mofetic) are known to cause harm to the baby if taken during pregancy, while breastfeeding, or even prior to conception. Other treatments such as steroids and ivig are less risky (but not zero risk). Women with myasthenia who are considering pregnancy should work very closely with a team including a neurologist experienced in the treatment of myasthenia gravis, an obstetrician and a neonatologist. This is the best way to reduce worry, and risk, as much as possible. For general information about myasthenia gravis, visit the myasthenia gravis foundation of america website at www.Myasthenia.Org. ...Read more

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Is myasthenia gravis disorder on agent orange list for benefits?

Contact the VA: This is a question for the va/dept of defense. Contact them to start the process. ...Read more

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What diseases are similar to myasthenia gravis?

Muscle weakness: Nerves and muscle disorders can give pictures similar to that of myasthenia gravis especially if the facial muscles and the muscles of the shoulder and pelvic girdle are involved. Please make sure that you have the proper diagnosis for myasthenia gravis. You will need blood tests for antibodies, and repetitive stimulation studies or even single fiber emg. You must be taken care of by a neurolog. ...Read more

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Which type of diseases could be mistaken for myasthenia gravis?

Rep stim studies: Many diseases that give few muscle weakness especially that of the muscles of the face, shoulder and pelvic girdle can give symptoms similar to myasthenia gravis. You need to have nerve conduction studies and repetitive stimulation studies to differentiate these diseases from one another. Please have yourself be evaluated by a neurologist or specialist in physical medicine and rehabilitation. ...Read more

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What happens in the disease myasthenia gravis?

Block receptor: Increased abnormal activity of the immune system can create antibodies that block communication between nerves and muscles. Specifically the nerve transmitter, acetylcholine (ach) is blocked from activating the ach receptor on muscles, which causes weakness. Mg can be treated by increasing the amount of ach reaching the receptor to overcome the blockade and by controlling the immune response. ...Read more

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What diseases could be mistaken for myasthenia gravis?

Muscle weakness: Other reasons for decreased use of muscles. This could be muscle diseases and neurological diseases. The usual clue is the occular involvement. ...Read more

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What kinds of diseases could be mistaken for myasthenia gravis?

Many conditions: Myasthenia gravis can mimic a large number of conditions, from muscle disease, ophthalmological disorders , general medical problems to anxiety state and psychological disorders. ...Read more

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What is dyemilinating disease & myasthenia gravis?

What is dyemilinating disease & myasthenia gravis?

Nerve disease: In patients with myasthenia, the acetylcholine receptor that helps form the neuromuscular junction is destroyed by the immune system. This causes nerves to be unable to trigger muscle contraction, leading to fatigable weakness. In demyelinationg disease, the myelin insulation surrounding the nerve is attacked by the immune system, disrupting signal transmission. ...Read more

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What other diseases can give the same symptoms as systemic myasthenia gravis when antibodies against the acetylcholine receptor are negative?

What other diseases can give the same symptoms as systemic myasthenia gravis when antibodies against the acetylcholine receptor are negative?

Anti-titin: There is a second type of antibody that is a perfect mimic. Eaton-Lambert antibodies are worth checking if you smoke. You may also be weak for other reasons, of if life's difficult, that itself can make you floppy and feel like you are getting MG. ...Read more

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Myasthenia gravis disease can be cured. Or take medicines long life?

No cure.: There is no cure for MG but the sufferer can lead a functional and happy life with the current treatments, such as Thymectomy, Plasmapheresis, VIG or immunoglobulin, corticosteroids for the acute process and immunosuppressants. The acetylcholinesterase and keep the disease in remission. Mestinon (pyridostigmine) helps keeps the choline-esterase in the neuromuscular junction is often used. ...Read more

Autoimmune (Definition)

The immune system developed to tell our own, normal cells (self) from foreign and abnormal cells (non-self). This lets the immune system eliminate viruses, bacteria, fungi and cancer cells from our body without harming normal cells. Sometimes the immune system fails to tell self from non-self and it attacks normal cells, for example in ...Read more


Dr. Julian Bragg
366 doctors shared insights

Myasthenia Gravis (Definition)

A chronic autoimmune neuromuscular disease characterized by varying degrees of weakness of the skeletal (voluntary) ...Read more