Top
10
Doctor insights on: Myasthenia Gravis

Share
Dr. Julian Bragg
358 doctors shared insights

Myasthenia Gravis (Overview)

Myasthenia gravis is an autoimmune condition in which the body produces a protein that blocks information transmission along nerves. This leads to symptoms such as droopy eyelids and weak muscles.


1

1
What is myasthenia gravis?

What is myasthenia gravis?

Fatigable weakness: Myasthenia gravis is an autoimmune disease that disrupts the neuromuscular junction, so that when motor nerves fire the muscle fibers do not reliably contract. It manifests as a "fatigable weakness" (one that gets worse with sustained effort) that can involve the limbs, the cranial nerves (hoarseness, double vision, difficulty swallowing), or, in some dangerous cases, muscles of breathing. ...Read more

See 2 more doctor answers
Dr. Julian Bragg
358 doctors shared insights

Myasthenia Gravis (Overview)

Myasthenia gravis is an autoimmune condition in which the body produces a protein that blocks information transmission along nerves. This leads to symptoms such as droopy eyelids and weak muscles.


2

2
How does mestinon (pyridostigmine) help myasthenia gravis?

How does  mestinon (pyridostigmine) help myasthenia gravis?

Activate muscle: Myasthenia disrupts the connection between nerve and muscle by reducing the number of receptors for a transmitter called acetylcholine. Mestinon (pyridostigmine) prevents acetylcholine from being broken down in the body, giving it more time to diffuse along the muscle and activate the remaining receptors. The net result is to restore effective transmission between nerve and muscle. ...Read more

See 1 more doctor answer
3

3
Are myasthenia gravis symptoms usually consistent throughout the day?

No, very variable: The hallmark of myasthenia is fatigable weakness that gets worse with activity. If the symptoms do not vary with time of day or activity, alternative (or additional) diagnoses should be considered. ...Read more

See 1 more doctor answer
4

4
What are the first symptoms of myasthenia gravis?

What are the first symptoms of myasthenia gravis?

Ptosis: Ptosis(droopiness of one or both eyes) or proximal muscle weakness of arm, thigh or neck. ...Read more

5

5
Need expert help here. What are some signs of myasthenia gravis?

Visual: Start out with double vision, droopy eyelids, and may just feel weak. A good evaluation from a neurologist is starting point if this is your concern. ...Read more

7

7
I went for a new member physical test for a merchant mariner job and put not fit for duty due to a new diagnose of myasthenia gravis, what to do?

Myasthenia gravis: This is a autoimmune neuromuscular problem that needs immediate attention. There is good treatment available. See myasthenia gravis foundation at www.Myasthenia.Org for lots of help finding the right doctors etc. ...Read more

See 1 more doctor answer
8

8
Does mestinon (pyridostigmine) effect diagnostic blood test results for myasthenia gravis?

NO, NOT AT ALL: Mestinon (pyridostigmine) enhances neuromuscular junctional efficiency by enhancing acetylcholine persistence, but is NOT an immune agent like a steroid. The standard testing for myasthenia gravis looks at antibody reactions, and would be positive or negative irregardless of use of Mestinon (pyridostigmine). ...Read more

9

9
Would the severity of symptoms of myasthenia gravis be visible in any blood tests?

May be: Severity of myasthenia gravis is a clinical issue and does not need lab tests. However lab tests are useful in diagnosis. See this site for more info. http://www.arupconsult.com/topics/mg.html. ...Read more

10

10
Recently diagnosed with myasthenia gravis and about to start mestinon (pyridostigmine). What do I need to know?

Recently diagnosed with myasthenia gravis and about to start mestinon (pyridostigmine). What do I need to know?

Symptom treatment: While myasthenia reduces the effectiveness of muscle activation, Mestinon (pyridostigmine) works to increase it. It works well and starts working quickly, but does not change the course of the underlying disease- typically an immune modifying drug is used in conjunction with it to prevent disease progression. Typical side effects include diarrhea, abdominal cramping, and muscle twitches. ...Read more

See 1 more doctor answer