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Doctor insights on: My Sister Has Polyarteritis Nodosa What Does This Mean

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Dr. Charles Lombard
158 doctors shared insights

Polyarteritis Nodosa (Definition)

Polyarteritis Nodosa is a condition in which blood vessels called arteries are swollen and damaged. This disease is more common in adults, and the tissues that are supplied by the blood ...Read more


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If my younger sister has polyarteritis nodosa, what is likelihood that her older brother myself, will have it too, i have no symptoms at the moment?

If my younger sister has polyarteritis nodosa, what is likelihood that her older brother myself, will have it too, i have no symptoms at the moment?

Unlikely: This is a very rare disease to have. It most commonly is associated with untreated hepatitis B virus. It can also be idiopathic, meaning, no associated cause is found. With autoimmune diseases in general, there is some inherited component typically, but it does not mean that exact disease will be inherited by another family member or that a family will even develop an autoimmune disease. ...Read more

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What causes polyarteritis nodosa?

What causes  polyarteritis nodosa?

Polyarteritis nodosa: Pan ( poly arteritis nodosa) is a disease of unknown cause.It affects small to medium sized arteries reducing or cutting off blood supply to organs . Men are affected more than women between ages of 30 to 50 . In 25% of patients hepatitis b or c infection is seen. Small and medium arteries are attacked by immune cells . It can affect infants. Dilated arteries and strictures resemble rosary beads. ...Read more

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What are the tests for polyarteritis nodosa?

Polyarteritis nodosa: Diagnosis made by clinical suspicion based on patient symptoms and findings .Lab findings may include elevated wbc, ESR , CRP and in some patients positive p-anca when pan involves small vessels , positive hep b or c ag or a/b in some patients . Angiogram shows typical beaded medium or small arteries with aneurysms. Biopsy of affected tissues shows arteritis. Sural nerve is commonly biopsied. ...Read more

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What are the symptoms of polyarteritis nodosa?

What are the symptoms of polyarteritis nodosa?

Ployarteritis nodosa: Symptoms depends on organ or system affected. Symptoms are fatigue , fever, muscle , joint pains, unexplained weight loss, anorexia . Based on organ involved kidney failure, hypertension due to kidney involvement, stroke , seizures due to brain involvement, abdominal pain due to bowel perforation , chest pain , heart attack due to heart involvement wrist drop, foot drop due nerve involvement. ...Read more

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I want to know my options for treating polyarteritis nodosa?

I want to know my options for treating polyarteritis nodosa?

Limited: Despite many trials, corticosteroids are still the cornerstone of treatment. Cyclophosphamide may be added in more severe cases or in resistant cases of polyarteritis that are not hepatitis b related. Newer agents to treat this condition exist and treatment should only be attempted by a physician intimately familiar with the condition. ...Read more

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What is inflammatory polyarteritis nodosa? How is it treated?

Inflammation - vesse: It is inflammation of blood vessels, Depending on which blood vessel are involved is where the symptoms and signs are. as the muscle is inflammed, the vessel narrows interferring with the blood flow. This is how polyarteritis causes its problems. The physician will evaluate the patient, get labs and perform imaging to help evaluate for therapy. ...Read more

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Can polyarteritis nodosa lead to vasculitic neuropathy?

Can polyarteritis nodosa lead to vasculitic neuropathy?

Yes but . . . .: Since pan is a vasculitis, it like the other rheumatological illnesses of this type can cause an associated neuropathy. It would be important to rule out other potential causes like medications, vitamin deficiencies, alcohol, infections, hereditary, diabetes, neurological conditions or vascular compromise. Others too. The onset, time course, distribution, and anatomy can help define it. Emg done? ...Read more

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What new research is there regarding vasculitis and polyarteritis nodosa?

What new research is there regarding vasculitis and polyarteritis nodosa?

Treatment.: Polaryarteritis & temporal arteritis, are found to be quite treatable without high dose Prednisone and all it's side effects. The new drugs are tnf-a inhibitors and new research shows quick remission in most cases. ...Read more

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Is polyarteritis nodosa an autoimmune disease?

Is polyarteritis nodosa an autoimmune disease?

Polyarteritis causes: The answer to your question is "it may be" an auto-immune disorder. Polyarthritis is most often caused by an auto-immune disorder such as rheumatoid arthritis, amyloidosis, psoriatic arthritis, and lupus erythematosus. In addition, it may also be caused by infection with an alphavirus such as chikungunya virus and ross river virus. Ask your physician for more information in your instance. ...Read more