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Doctor insights on: My Chronic Pain Meds Stop Working Is There Such Thing As Drug Holidays

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My chronic pain meds stop working. Is there such thing as drug holidays?

My chronic pain meds stop working. Is there such thing as drug holidays?

Yes: A "drug holliday" is a period of time when you stop taking medication. The idea is to give your body a chance to cleanse itself and get rid of drug metabolites. It is thought that the drug will be more effective after a period of time off the drug. Another means of obtaining increased effect from pain medications is to change to another drug. This is called opioid rotation. ...Read more

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Dr. Praveen Mambalam
374 doctors shared insights

Persistent Pain (Definition)

Persistent pain is pain that occurs most of the day, on most days. Pain that last for more than 4-6 months is called chronic pain. Persistent pain doesn't go away in an expected time frame for the injury. for example, your doctor says it'll be fine in a couple of weeks; if the pain is still present, more days than not, at 3-4 weeks out, its persistent. And, it should be ...Read more


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I take other medications for other medical issues as well. Gralise is what the pain management doctor prescribed on my first visit. It's not doing muc?

I take other medications for other medical issues as well. Gralise is what the pain management doctor prescribed on my first visit. It's not doing muc?

Tell Dr of ALL meds!: Be sure that ALL doctors you see know about ALL meds you take. They need to know and your telling/reminding can really help. Also, if any seem to be ineffective or causing any side effects, discuss it ASAP. That's a big part of treatment. ...Read more

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What is the best longterm treatment for drug induced GERD and epigastric pain if someone take meds for chronic conditions,&name of drug please?

What is the best longterm treatment for drug induced GERD and epigastric pain if someone take meds for chronic conditions,&name of drug please?

Depends: The best drug for you depends on many factors, including what other medical conditions you have and medications you take. An antihistamine acid blocker or a proton pump inhibitor are most commonly prescribed to treat GERD. (examples are ranitidine or omeprazole) ...Read more

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I'm an addict foremost. Is there anything for pain in between nsaids and narcotics? Tordol works but why can it only be used sparingly?

I'm an addict foremost. Is there anything for pain in between nsaids and narcotics?  Tordol works but why can it only be used sparingly?

Stomach: Toradol is just a strong nsaid; try tylenol (acetaminophen) with aleve, they work by differing mechanisms. If you have chronic pain problems you may benefit from a low dose of suboxone. Pain issues can be pert of a spectrum of mood problems and may be linked to addiction and mood. Also the snri class of antidepressant is good for pain. Cymbalta at 30 mg is not addictive and indicated for arthritis. Good luck. ...Read more

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Is oxycontin bad for you longterm if used as prescribed (the same way benzos can have longterm negative effects)? My headache pain is too awful

Is oxycontin bad for you longterm if used as prescribed (the same way benzos can have longterm negative effects)?
My headache pain is too awful

Possibly: Oxycontin is an opiate, and may lead to dependence. In addition, your headache called an opiate withdrawal headache. I would recommend seeing your primary care provider or a neurologist to figure what's causing your headaches. (Migraines?/ Cluster headache?/ Tension headache/ withdrawal?/etc...) ...Read more

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Is it ok to take marajuana with other medicines for pain control ?

 Is it ok to take marajuana with other medicines for pain control ?

Usually: As long as you have had the pain properly evaluated to eliminate causes amenable to other methods, then marjijuana can be added to the mix to provide more effective control. It is helpful if you are in WA state or Colorade where this has been legalized for this purpose although be mindful that it is still illegal under Federal law. ...Read more

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I've tried all different meds for my idiopathic leg pain. No one can find the source. If opiods are the next step, is Tapentadol a good choice ?

I've tried all different meds for my idiopathic leg pain. No one can find the source. If opiods are the next step, is Tapentadol a good choice ?

Neuropathy: after dealing with thousands of cases of "leg pain", my guess is that you have a neuropathy. the problem I have seen is that when the testing comes back normal, i.e. nerve conductions studies and EMG, they assume nothing is wrong. The testing doesn't have to be abnormal to have a neuropathy, i.e. sensory neuropathy. yes, I really like nucynta (tapentadol) for neuropathic pain. ...Read more

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What's an alternative to norco (hydrocodone and acetaminophen) for pancreatitis pain? Prefer something less harsh on liver, but pain control is a must as it is debilitating sometime

What's an alternative to norco (hydrocodone and acetaminophen) for pancreatitis pain? Prefer something less harsh on liver,  but pain control is a must as it is debilitating sometime

Tramadol: Tramadol may be helpful, however check with your other medications as it is know to have interactions with other meds. Otherwise, you could try nsaids, muscle relaxants or even meds like gabapentin/lyrica to help. ...Read more

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Is there really a thing such a chronic bck pain and taking pain killer forever?

Depends: You are very young to have chronic back pain. Physical therapy would be the best initial treatment. You may need to see a doctor as there are other ailments which you may have that can be treated. ...Read more

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What is the main reason for suffering from colic and (wind) because i took some medications such as jasicone (105.8 mg simethicoe)?

What is the main reason for suffering from colic and (wind) because i took some medications such as jasicone (105.8 mg simethicoe)?

GI UPSET: You probably have hyperacidity that needs to be neutralized by antacid. If you feel good after taking rx, then next time make sure to eat on time so your stomach will not be colicky. ...Read more

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I'm taking meds for my fibromyalgia but is there anything else i can do such as diet, exercises, vitamins?

I'm taking meds for my fibromyalgia but is there anything else i can do such as diet, exercises, vitamins?

Psychotherapy: Can help cope with the challenges fibromyalgia doles out including pain and stress management. Support groups if available also are helpful. Many people do not understand or want to hear about it, so finding others who understand and can be supportive is important. ...Read more

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How common is urinary retention from chronic use of zyrtec (cetirizine)? Any other side effects? I was prescribed to take it everyday but doc never mentioned this

How common is urinary retention from chronic use of zyrtec (cetirizine)? Any other side effects? I was prescribed to take it everyday but doc never mentioned this

Not common: Any antihistaminic can cause urine retention, but it's a rare side effect, other side effects such as dry mouth, somnolence r more common, usually common side effects r written on the patient info leaflet dispensed with drugs, or on boxes for over-the-counter meds. ...Read more