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Doctor insights on: My Brother Has Myelodysplastic Syndromes Should I Be Worried About This

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My brother has myelodysplastic syndromes. Should I be worried about this?

My brother has myelodysplastic syndromes. Should I be worried about this?

Possibly: This would depend upon your brothers age, and his risk factors. For instance if he is elderly, and has significant chemical exposure, than no. If he is young, under the age of 50, mds is uncommon and i would seek a second opinion to confirm the diagnosis. If it turns out to actually be mds than yes, you would be at a higher risk. ...Read more

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Myelodysplastic syndromes are what?

Blood disease: These are a group of blood disorders that cause anemia or problems with the white cells, platelets or all three. There are several different forms that have varied prognosis. Some are very close to leukemia. These are diagnosed on bone marrow testing. There are some damaged chromosomes that can be found with this group of diseases. Some are very treatable, and some not so. ...Read more

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What are the tests for myelodysplastic syndromes?

Bone marrow: The only way to diagnose a myelodysplastic syndrome completely and accurately including prognostic factors is by performing a bone marrow biopsy and aspiration with subsequent multi-pronged assessment: morphology, flow cytometry, cytogenetics, and molecular studies. Some changes in the peripheral blood may suggest mds but a complete diagnosis still relies on bone marrow examination. ...Read more

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Are some people more prone to getting myelodysplastic syndromes?

Yes: There are some risk factors for myelodysplastic syndrome(mds). People exposed to certain chemotherapy drugs are at increased risk due to damage to the bone marrow dna from some chemo drugs. There is a higher risk of mds as people age. Certain genetic disorders (such as down syndrome) put people at risk for mds. Tobacco use is also associated with an increased risk of mds. ...Read more

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What are the symptoms of myelodysplastic syndromes (mds)?

What are the symptoms of myelodysplastic syndromes (mds)?

It varies: There may be none or the patient may feel tired from anemia, show signs of bruising from low platelets or infections from low white blood counts. ...Read more

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Are there treatment guidelines for myelodysplastic syndromes?

Are there treatment guidelines for myelodysplastic syndromes?

Yes: Nccn, a nationaly recognized organization publishes guidlines for the treatments of all malignancies including mds. ...Read more

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What is myelodysplastic syndromes (mds)?

Bone marrow disease: MDS is a disease of bone marrow that causes blood precursor cells to have an abnormal appearance ("dysplasia"), and prevents normal production of mature RBC or WBC. This can cause seriously low blood cell counts. It arises from gene mutations acquired during your lifetime, in bone marrow cells. There is a risk that, with additional mutations, it can evolve into acute leukemia. ...Read more

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What are effective treatments for myelodysplastic syndromes (mds)?

What are effective treatments for myelodysplastic syndromes (mds)?

Treatment options: As mentioned it depends on the clinical situation. Sometimes treatment is just with observation, transfusions when needed. Drugs called growth factors can be used in some situations. There are some chemotherapy drugs that are effective and for aggressive cases a stem cell transplant can be used. ...Read more

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Are there any herbal supplaments that may help my mom who has myelodysplastic syndromes?

Are there any herbal supplaments that may help my mom who has myelodysplastic syndromes?

MDS: B12, Folate, (folic acid) Fe: Supplements in MDS is complex and depends on patient blood levels. In general, B12, folate (folic acid), (folic acid) and iron levels should be checked. If B12 or folate (folic acid) levels are low, then these should be replaced because they can help with red blood cell production. Iron can be normal or high in MDS. I generally recommend avoiding iron because many MDS patients can become iron overloaded by blood transfusions. ...Read more

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