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Doctor insights on: Multiple Sclrosis

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Is multiple sclerosis hereditary?

Is multiple sclerosis hereditary?

Complex: Multiple sclerosis is an issue of genetic susceptibility, not the usual heredity, and risk runs about 3-5% if mother has it, 1-2% if father has it. But without specific environmental triggers, the disease will be unlikely to manifest. ...Read more

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Dr. Hamid Sajjadi
3 doctors shared insights

Sclerosis (Definition)

We neurologists employ the term to describe localized damage involving the central nervous system, and sclerosis means scarring. If in many areas, might be multiple sclerosis. If affecting the motor nerve cell, ...Read more


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Is multiple myeloma hereditary?

Is multiple myeloma hereditary?

Rarely: There are a few families where it appears hereditary. Having said this, there are families where more than one individual has the disease and the thought is that this may be due to an environmental cause. ...Read more

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Is multiple sclerosis preventable?

Is multiple sclerosis preventable?

No: Population studies have suggest that mononucleosis in adolescence, smoking, and possibly childhood obesity are risks for developing ms. However ms is a complex variable disease requiring genetic predisposition along with some environmental trigger(s), possibly influenced by hormones, immune system priming from certain infectious agents. ...Read more

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Is multiple myeloma genetic?

Is multiple myeloma genetic?

Yes/No: In a sense all cancer is "genetic" involving changes to the DNA or epi-genetic - changes to DNA modifiers such as methylation. A related question is is multiple myeloma inherited. The answer is sometimes. The risk is about double with a family history. Here is one clinical trial studying this: https://clinicaltrials.gov/ct2/show/NCT00582621 ...Read more

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Is multiple sclerosis fatal?

Is multiple sclerosis fatal?

Not usually: Ms is a chronic neurological condition, characterized by episodes of neurological disability of variable severity and recovery. A minority of inidividuals can have a very aggressive course, and become so disabled that they are at risk of secondary medical complications which may be fatal. There are subtypes of MS which are so aggressive that a fatal outcome can happen. Fortunately these are rare. ...Read more

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Multiple sclerosis = demyelination?

Multiple sclerosis = demyelination?

Characteristic: Demyelination refers to damage to the coverings of the nerves in the brain and spinal cord, and is very characteristic of the inflammatory process that occurs in ms. This can also occur in children with hereditary leukodystrophies, and can be associated with acquired neurological disorders. The disease modifying drugs in MS are designed to control demyelination and many work well. ...Read more

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What symptoms of ms multiple sclerosis ?

What symptoms of ms multiple sclerosis ?

Variable: Please consult this site for information on early symptoms of MS http://www.webmd.com/multiple-sclerosis/guide/multiple-sclerosis-symptoms Wish you good health. ...Read more

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What disease might mimic multiple sclerosis?

What disease might mimic multiple sclerosis?

Several potentials: Cadasil, lupus, arteritis, clippers, pernicious anemia, cervical spondylosis, lyme disease, CNS lymphoma, sjogren's, melas. If you get the point, ms may be hard to diagnose, and often need to exclude other explanations. Patterns may or may not be different, and sometimes it is important to get testing and even several opinions. ...Read more

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What is multiple sclerosis? What is multiple sclerosis?

What is multiple sclerosis? What is multiple sclerosis?

What is MS: Multiple sclerosis is an autoimmune disease that affects the brain, spinal cord, and / or optic nerves. It may cause attacks of symptoms or follow a progressive course. It may affect different areas of the these body parts at different times over many years. It may be either aggressive or benign. ...Read more

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What multiple is sclerosis? What multiple is sclerosis?

What multiple is sclerosis? What multiple is sclerosis?

Multiple : Multiple sclerosis is an autoimmune disease that affects the protective covering around nerves in the spinal cord and brain. I've attached a few good websites below that discuss ms in much more detail. ...Read more

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What is multiple sclerosis? What is multiple sclerosis?

Multiple Sclerosis: http://www.ncbi.nlm.nih.gov/pubmedhealth/pmh0001747/.

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What is multiple sclerosis? What is multiple sclerosis?

What is multiple sclerosis? What is multiple sclerosis?

Multiple sclerosis : Multiple sclerosis is a neurological disorder in which the brain and spinal cord become the target of our own immune system. The myelin, important brain substance that facilitates brain cell communication, gets damaged in multiple areas over time as result of this inflammatory response. Patients symptoms may vary based on the area affected by the inflammation or demyelination. ...Read more

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What is multiple sclerosis?

Autoimmune condition: It is a condition where your own immune system attacks the sheaths (myelin) which covers your nerve fibers. Common symptoms include weakness in muscles due to slow/ damaged nerve conduction. Lowering Inflammation in your body via diet, stress reduction, anti-inflammatory supplements may delay, stabilize and improve the condition. ...Read more

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What are neuropsychiatric problems associated with multiple sclerosis ?

What are neuropsychiatric problems associated with multiple sclerosis ?

Significant at times: Main issue is evolution of progressive cognitive loss, which likely is present in at least 60% and creates an early disability. Lack of emotional control, such as crying or laughing without reason, or more persistent euphoria or depression gets even more challenging. Although delusions and hallucinations may be rarely seen, usually not an issue. ...Read more

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Is amyotrophic lateral sclerosis a type of multiple sclerosis (ms)?

Is amyotrophic lateral sclerosis a type of multiple sclerosis (ms)?

Not similar diseases: Als is very different, and is a disease of "mis-folded proteins" like alzheimers and parkinson's, and all of these affect older people. Ms is an autoimmune disease afflicting younger patients who have hereditary susceptibilities and environmental exposures. Ms can be successfully treated and controlled, but ALS does not respond well to current therapies. ...Read more

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Is multiple sclerosis a hereditary condition?

Is multiple sclerosis a hereditary condition?

In part: Hereditary risk is one factor, but the interplay between genetic background and environment is likely in this disease. Identical twins studies show about a 30% risk for MS if one twin has the disease (certainly not 100%). Population studies show certain ancestry may increase or decrease risk (e.g. Northern european ancestry high, whereas asian, african, aboriginal very low). ...Read more

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Common symptoms of multiple sclerosis?

Common symptoms of multiple sclerosis?

Varies, but often: The disease can present with loss of vision in one eye, electrical tingling on bending the neck, unexplained imbalance or falling, leg weakness and/or spasticity, bladder incontinence, fatigue, double vision, and problems with intellectual function. This can be isolated or grouped, and in 85% if pts symptoms come on rapidly and slowly remit, i.e., relapsing-remitting ms. Start rx asap. ...Read more

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What are signs of multiple sclerosis?

Many: Ms can present with a host of physical findings including optic neuritis, unilateral weakness and numbness, a band-like sensation around your chest or abdomen, hearing loss, gait ataxia, slurred speech, urinary incontinence, bilateral upper extremity/lower extremity weakness. Typically the initial presentation in the young may be a single symptom (optic neuritis), however hemiparesis is seen. ...Read more

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Is primary progessive multiple sclerosis always fatal?

Is primary progessive multiple sclerosis always fatal?

Not necessarily : Ms has been said to shorten life span, and untreated this is correct, but several studies have supported normal life if appropriate potent meds are employed. Primary progressive ms does not respond well to the usual meds, and mostly symptomatic interventions are used. There are many research projects nowadays, and best to contact a medical school and get involved. ...Read more