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Multiple Sclerosis Panel
Autoimmune: Ms is a disease where the immune system attacks the coverings of nerves in the brain and spinal cord. Susceptibility due to heredity and environment seem to affect who gets afflicted. The prognosis is improving dramatically these days due to new medicines. Therapies include tysabri, (natalizumab) gilenya, copaxone, betaseron, rebith, extavia, etc. ...Read more
A research study: Actually, no such terminology has been introduced yet, since we are in very early stages of examining the potential of stem cells to treat ms patients. Some of this is being done in europe, and expect more in future. Outcomes unclear currently, but stay tuned. ...Read more
Autoimune regulation: Increasing evidence points to the common link of failure of the auto immune system and progressive systemic disease in people who were otherwise healthy at birth. The immune systems can be overwhelmed by toxic exposures, food allergies, physical and mental stress, infectious disease, intestinal dysbiosis and lack of sufficient nutrients to generate the reserves we need to keep the body healthy. ...Read moreSee 1 more doctor answer
See below: 85% of all initial ms diagnoses are for relapsing-remitting forms, but about 10% are primary progressive with slow gradual deterioration without exacerbations or improvement. When the r/r form gets out of control, by 10-20 yrs , there is also a steady progression, secondary progressive ms. A rare form, called progressive relapsing is a mix of both. ...Read more
See below: Autoimmune type of attack on brain, spinal cord, and optic nerves in genetically susceptible young individuals, who are exposed to a variety of environmental events. Can lead to profound impairment and disability, but can be controlled and stabilized in most cases with modern potent meds. An expert neurologist who is experienced can work wonders. ...Read more
Try this approach: Do you or anyone close have ms? It is important to understand that we have 9 medications on the market, and not all pts are appropriate for all. I do recommend that most pts take the most potent meds, such as tysabri (natalizumab) or gilenya, maybe tecfidera as a third choice. Information can be found at aan.Com, and your local ms society, but need neurologist to help select correct med. ...Read more
Variable: Copaxone (glatiramer) is a first line agent which may not be useful for many pts, and may take up to 4-6 months to reach maximal potency in some pts. If relapses continue to occur, and your MRI shows active lesions, other meds may be better choices for you. Discuss thoroughly with your neurologist. ...Read more
My wife is 37 and has multiple sclerosis. She wants to get pregnant but i'm afraid that stopping her medication will do her harm. Is it safe?
Multiple sclerosis: It is a concern. Removing certain medications can increase the relapse rate immediately after stopping the medication (immune reconstitution syndrome). This is not seen with the older "platform" therapies. Copaxone (glatiramer) is category b for pregnancy. Nevertheless, all my patients have opted to stay off medication during their pregnancies. Good thing is relapse rate is reduced during 2-3rd trimester. ...Read moreSee 3 more doctor answers
Is it safe for people who have multiple sclerosis to go under anesthesia for a mini tummy tuck? If I have ms, can I safely go under anesthesia in order to have a mini tummy tuck?
Many conditions: Initially the ms patient goes through many diagnostic considerations. Stroke, drug effects, malingering, viruses, toxic reactions, lupus, pinched nerves, are just some of the common initial concerns. It may take hundreds of tests and repeated bouts before a definite diagnosis can be made. ...Read moreSee 1 more doctor answer
Risk: liver tóxic: In excessive amount may be seriously toxic to the liver ( not in usual prescribed dosis). Since there is nothing proven to cure multiple sclerosis you should ask whoever recommended it what is suppose to do. It is considered an opium antagonist. Hopefully your neurologist is aware. Do not take it unless supervised by someone experienced in using it for ms. ...Read moreSee 1 more doctor answer
Actually common: A variety of painful symptoms can occur. Some studies suggest up to 60 % of ms pts can encounter pain. Severe facial pain (tic doloureux), spasms associated with spasticity, vague discomfort in legs, feet, arms, and electrical sensations down the spine are among the symptoms. ...Read moreSee 1 more doctor answer
I am 30 yrs old painful stomach probs headaches menstrual probs and generally pain all over could this be fibromyalgia or multiple sclerosis?
Not Ms: Multiple sclerosis is not commonly associated with gastrointestinal symptoms or headache. Recurrent headaches in young people, especially when pulsatile, unilateral, lasting hours, causing nausea and disability, are usually due to migraine. Sometimes migraine patients can also suffer from other problems such as fibromyalgia or irritable bowel syndrome. Menstrual probs not typically related. ...Read moreSee 1 more doctor answer
What symptoms: Multiple sclerosis is a disorder of the central nervous, the brain and spinal cord of unknown etiology, due to inflamation of the nerves. You can have pain with multiple sclerosis, usually due to involvement of the spinal cord. Hard to answer question without knowing what you mean by symptoms of multiple sclerosis. Too many potential symptoms to list here. ...Read moreSee 1 more doctor answer
Help! is multiple sclerosis a result of single or multiple gene disorder or a chromosomal abnormality?
Not genetic mostly: There are no signs that multiple sclerosis is a sign of a chromosome disorder. Although there is likely a genetic component, this appears to be a very small role. This is not the type of disease where if you have the gene, you get the disease. It tends to be sporadic. It is an auto-immune disease where antibodies attack the white matter of the brain and/or spinal cord. ...Read moreSee 1 more doctor answer
MRI DATA: The diagnosis is certainly based on history and exam, but the MRI is also confirmatory. We discuss "dissemination in time", with lesions emerging and disappearing on serial studies. Also, "dissemination in space", with lesions in different parts of brain and/or spinal cord. Location of lesions are helpful. If there is indication of active inflammation, this prompts aggressive therapy. ...Read more
Uhthoff's phenomenon: Ms used to be diagnosed using the "hot tub test": demyelination, or loss of insulation around nerve fibers in the brain or spinal cord can slow or drop the impulse when core body temperature rises. It is reversible, and causes no permanent damage. A patient with ms put in a hot tub may find the legs become numb and heavy, thus needing help getting out! ...Read moreSee 2 more doctor answers
I was wondering how many lesions a year were considered normal for relapseing remitting multiple sclerosis in a young adult? 25yrs old.
Predicting Outcome: Factors that predict unfavorable prognosis are: 1. Primary or secondary progressive course 2. Older age at onset (> 25) 3. Male sex 4. First interval between attacks shorter than one year 5. Initial cerebellar or pyramidal (motor) symptoms 6. Moderate to severe disability within the first 2 years. Link to more info: http://www.Ncbi.Nlm.Nih.Gov/pmc/articles/pmc1073365/pdf/jnnpsyc00027-0030.Pdf. ...Read moreSee 2 more doctor answers
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