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Doctor insights on: Multiple Schlerosis Society

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Who discovered multiple sclerosis?

Who discovered multiple sclerosis?

Charcot: The French neurologist Charcot is credited with identifying MS as a distinct entity for the first time. ...Read more

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Dr. Jan Lei Iwata
3 doctors shared insights

Sclerosis (Definition)

We neurologists employ the term to describe localized damage involving the central nervous system, and sclerosis means scarring. If in many areas, might be multiple sclerosis. If affecting the motor nerve cell, ...Read more


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Optic neuritis (nmo) or multiple sclerosis (ms)? What are the different victims?

Optic neuritis (nmo) or multiple sclerosis (ms)? What are the different victims?

Say what???: This question is confusing! optic neuritis (abbreviated on) is one of many symptoms of ms and results from inflammation in one or both optic nerves. It is one of the most common symptoms of ms and typically causes eye pain and decreased vision in one eye. It does not typically cause complete blindness. Multiple sclerosis (ms) is an autoimmune disorder of the center nervous system. See below. ...Read more

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Is multiple sclerosis hereditary?

Is multiple sclerosis hereditary?

Complex: Multiple sclerosis is an issue of genetic susceptibility, not the usual heredity, and risk runs about 3-5% if mother has it, 1-2% if father has it. But without specific environmental triggers, the disease will be unlikely to manifest. ...Read more

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Is multiple sclerosis preventable?

Is multiple sclerosis preventable?

No: Population studies have suggest that mononucleosis in adolescence, smoking, and possibly childhood obesity are risks for developing ms. However ms is a complex variable disease requiring genetic predisposition along with some environmental trigger(s), possibly influenced by hormones, immune system priming from certain infectious agents. ...Read more

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What's the present mortality rate of multiple sclerosi. Are there surgical options for multiple sclerosis?

What's the present mortality rate of multiple sclerosi. Are there surgical options for multiple sclerosis?

Two questions: 1. There is no surgical process that will beneficially help ms, other than possibly deep brain stimulation to control cerebellar tremors. 2. If treated with a potent medication, the lifespan should be similar to a patient without ms. 3. Forget this business with surgery to veins draining from the brain, it is life-threatening and does not work. ...Read more

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What's are future treatments for amyotrophic lateral sclerosis (als)?

What's are future treatments for amyotrophic lateral sclerosis (als)?

Hope it arrives.: There is a lot of research and we have identified a misfolded protein as playing a role (superoxide dismutase). But we do not have a cure. Best we can do is Riluzole and palliative supportive care at this time. However, a variety of meds and approaches are being studied. Stayed tuned. ...Read more

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Is multiple myeloma genetic?

Is multiple myeloma genetic?

Yes/No: In a sense all cancer is "genetic" involving changes to the DNA or epi-genetic - changes to DNA modifiers such as methylation. A related question is is multiple myeloma inherited. The answer is sometimes. The risk is about double with a family history. Here is one clinical trial studying this: https://clinicaltrials.gov/ct2/show/NCT00582621 ...Read more

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Doctors, what are the major downsides of multiple myeloma cancer?

Bone pain possible: Multiple myeloma is a malignant proliferation of plasma cells. This is a serious disease that can be fatal without treatment. Some symptoms include possible recurrent infections, bone pain, poor circulation, and kidney impairment. If you are concerned about myeloma please talk with your doctor. Use this link: http://my.Clevelandclinic.Org/disorders/multiple_myeloma/bm_overview.Aspx. ...Read more

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Is amyotrophic lateral sclerosis a type of multiple sclerosis (ms)?

Is amyotrophic lateral sclerosis a type of multiple sclerosis (ms)?

Not similar diseases: Als is very different, and is a disease of "mis-folded proteins" like alzheimers and parkinson's, and all of these affect older people. Ms is an autoimmune disease afflicting younger patients who have hereditary susceptibilities and environmental exposures. Ms can be successfully treated and controlled, but ALS does not respond well to current therapies. ...Read more

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What are neuropsychiatric problems associated with multiple sclerosis ?

What are neuropsychiatric problems associated with multiple sclerosis ?

Significant at times: Main issue is evolution of progressive cognitive loss, which likely is present in at least 60% and creates an early disability. Lack of emotional control, such as crying or laughing without reason, or more persistent euphoria or depression gets even more challenging. Although delusions and hallucinations may be rarely seen, usually not an issue. ...Read more

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Best multiple sclerosis medications?

Interferons ? : There is no best medication , some would suit the patient better than others but interferons are the most widely used for prevention of attacks. ...Read more

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Doctors, what are the genetic links with MS and motor neurone disease (als)?

None : Als and ms are completely different disorders, and have no known common genetic profiles. ...Read more

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Is there research into any genetic, autoimmune or other condition that links nerve sheath disorders (tarlov cysts, nerve sheath tumor) with autoimmune hypophysitis targeting acth cells? Ctla-4 gene?

Is there research into any genetic, autoimmune or other condition that links nerve sheath disorders (tarlov cysts, nerve sheath tumor) with autoimmune hypophysitis targeting acth cells? Ctla-4 gene?

None that I find: I cannot locate any literature on the two conditions being studied simultaneously. Perhaps one of my more research savvy colleagues here will come up with something . Great question by the way. ...Read more

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Are multiple sclerosis and myasthenia gravis conditions of the neuroglia?

Are multiple sclerosis and myasthenia gravis conditions of the neuroglia?

Neither of them: Neither of these conditions is a condition of the neuroglia. To some extent, glial cells are involved in the repair of damage that occurs in MS. Myasthenia is a condition that occurs at the junction of the nerve and muscle, no glia cells are present there. ...Read more

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How many people have multiple sclerosis?

How many people have multiple sclerosis?

200 cases each WK: It is estimated approximately 250, 000. To 350, 000. People are affected in usa and 200 cases are diagnosed each week. ...Read more

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Is there treatment of multiple scelerosis desease?

Yes: Nmss.Org msaa.Org there are several approved therapies. If you have been diagnosed with ms then surely the doctor who made the diagnosis has discussed this with you. ...Read more

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What disease might mimic multiple sclerosis?

What disease might mimic multiple sclerosis?

Several potentials: Cadasil, lupus, arteritis, clippers, pernicious anemia, cervical spondylosis, lyme disease, CNS lymphoma, sjogren's, melas. If you get the point, ms may be hard to diagnose, and often need to exclude other explanations. Patterns may or may not be different, and sometimes it is important to get testing and even several opinions. ...Read more

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Multiple sclerosis TMJ. Any relationship? I read some article about similar symptomps

Multiple sclerosis TMJ. Any relationship? I read some article about similar symptomps

No: Multiple sclerosis is strictly a disease of the brain and spinal chord and doesn't affect the joints. If you have one autoimmune disorder like MS, you can however be prone to another like rheumatoid that can cause arthritis, including arthritis of the TM joint. ...Read more

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Is multiple sclerosis a hereditary condition?

Is multiple sclerosis a hereditary condition?

In part: Hereditary risk is one factor, but the interplay between genetic background and environment is likely in this disease. Identical twins studies show about a 30% risk for MS if one twin has the disease (certainly not 100%). Population studies show certain ancestry may increase or decrease risk (e.g. Northern european ancestry high, whereas asian, african, aboriginal very low). ...Read more

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