Doctor insights on:
Multiple Myeloma With One Kidney
I had not heard of "kahler's disease" until seeing multiple questions on healthtap. It is multiple myeloma (mm). "multiple" is from the often seen "multiple" bone lesions (especially in advanced disease). Mm is a cancer of plasma cells [highly specialized b white blood cells (lymphocytes)] that produce antibodies. Sx are crab: hypercalcemia, renal insufficency, anemia, ...Read more
Depends: This can best be answered by your treating physician. It often depends on age, other medical disorders, previous treatments, response to velcade (bortezomib). Most patients will have improvement in renal failure if this is the first treatment they receive, and the treatment usually includes velcade (bortezomib). ...Read more
Immunosuppression: I am not a kidney transplant specialist, but i still think i can answer. Patients that receive an organ transplant usually need ongoing immunosuppression to prevent rejection. That can include a variety of drugs including steroids. Diabetes, bone loss - steroid induced cancer - immunosuppression drugs. ...Read moreSee 1 more doctor answer
It depends: Survival in myeloma depends on a number of factors. First, is stage. Second is chromosomal abnormalities. Some have a good prognosis, others not so good. In general we think that myeloma is not usually curable with standard therapies, but survival is getting better with our newer agents, so that living 10 years is not unusual. Cure may be possible with allogeneic bone marrow transplant. ...Read more
What is the prognosis of life expectancy of someone diagnosed with NSCLC WITH mets to, liver, multiple bones, multiple lymph nodes and brain?
NSCLC: Unfortunately, the prognosis isn't good. One year survival is about 30%. 5 year survival with distant mets is less than 4%. Just remember that statistics are valid for groups. Who knows what grace God might bestow on any individual? ...Read more
What medications for peripheral neuropathy are safest for someone with reduced kidney function (gfr = 38, all other kidney tests are normal)?
Good article: Try this article by mayo clinic: http://www.Mayoclinic.Com/health/kidney-failure/ds00682. ...Read more
Multiple parenchymal nodules less than 4mm & multiple pleural nodules less than 5mm with a dominant nodule 6.4mm all solid in lower lobes next action?
Mgt: The cause of the nodules can be further assessed by a biopsy, screening of washings for infections and malignancy. Are you a smoker? do you have a family history of lung cancer? At your age without risk factors, lung cancer is not likely. I would suggest an appointment with your pulmonary specialist. ...Read more
Ultrasonography of 68 yr male parkinson patient: echogenic renal cortices-could be parenchymal disorder & lots of residual urine (59 cc).Is it risky?
Ultrasound: Echogenic kidneys on ultrasound may represent medical renal disease. This should be correlated with the patient's renal function and BUN and creatinine. A valatta with a large amount of urine may be normal. A pre-and post void bladder sonogram should be performed. This may be related to a enlarged prostate or a neurogenic bladder. Discuss with nephrologist/urologist. ...Read more
About bilateral multiple renal stones the largest being 12mm and 7mm on each and a renal cyst 15mm x 13mm, what is the best treatment.
Renal stone: Most renal cyst or insignificant and required no treatment. The nonobstructing renal stones are best treated with eswl. See a urologist to discuss treatment options. ...Read more
Can taking high doses of vitamin d3, 5000 iu's daily for two years straight cause me to have multiple tiny kidney stones in both kidneys?
Yes. Not common.: Yes. Multiple myeloma can effect any organ. However, liver involvement is not common. Myeloma generally involves the bones predominantly; however there are reports of nearly every organ being involved in including the brain. Liver involvement by any cancer can make some types of chemotherapy (that is processed by the liver) more difficult to give. ...Read moreSee 1 more doctor answer
Pink urine and minor irritation in 34 year old male cumadin patient with history of kidney stones. X-ray shows one kidney larger . Scared any answer?
Not necessarily bad: Will need evaluation to locate the source of bleeding. Could be kidney stone, but there are many other possibilities. Kidneys are often different in size and this may not be related at all. See the doc who ordered your studies. ...Read more
Is increase in plasma cell 15 percent only related to multiple myloma of other malignancies or infection also?
Myeloma or infection: Multiple myeloma is based on all three of the following for diagnosis: 1) 10% or more monoclonal plasma cells; 2) serum or urine monoclonal protein; 3) organ dysfunction (high serum calcium, high serum creatinine, low hemoglobin, or lytic bone lesions/osteoporosis). If 2) is not present, then bone marrow needs 30% plasma cells. Plasma cells can occur with infections. See a doctor for further help ...Read more
Is it common for a 36y pt to have multiple bilateral renal cysts, hepatic cysts, splenic cyst, and adrenal cyst all at once? Shall i worry about mets?
Something else : Do you have a diagnosis? Family history of polycystic kidney disease? Radiologist is probably best dr to talk to as will correlate your history with specific cyst patters seen on imaging. Will also be able to recommended additional diagnostic tests & use intervention techniques to diagnose, drain & treat as needed. Apckd > hydatid cysts can do this. Confirm its adrenal cyst vs adenoma, . ...Read moreSee 1 more doctor answer
The kidneys are paired organs that lie on either side of the vertebral column. Part of their critical functions include the excretion of urine and removal of nitrogenous wastes products from the blood. They regulate acid-base, electrolyte, fluid balance and blood pressure. Through hormonal signals, the kidneys control the ...Read more
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