Multiple myeloma - Doctor answers

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Dr. Liawaty Ho
753 Doctors shared insights

Multiple Myeloma (Overview)

A cancer of the plasma cells, which are responsible for producing antibodies for your body. Symptoms include kidney insufficiency, anemia, bone disease, infections, and pain.


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What other tests for multiple myeloma?

What other tests for multiple myeloma?

Blood/Urine/Imaging: Usually workup involves blood and urine tests (spep / upep - serum and urine protein electrophoresis). The preferred initial imaging study is the skeletal survey (x-ray of multiple sites of the body including skull, axial skeleton, and proximal long bones). Bony lesions are usually lytic. ...Read more

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Dr. Liawaty Ho
753 Doctors shared insights

Multiple Myeloma (Overview)

A cancer of the plasma cells, which are responsible for producing antibodies for your body. Symptoms include kidney insufficiency, anemia, bone disease, infections, and pain.


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What is the symptoms for multiple myeloma?

What is the symptoms for multiple myeloma?

Many symptoms: There may be no symptoms in some people who are found to have myeloma on routine blood tests. Common symptoms include back pain, fatigue, bone fractures. Nausea and vomiting can occur related to kidney or electrolyte problems. ...Read more

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What are your treatment options for multiple myeloma?

What are your treatment options for multiple myeloma?

Many: There are many options. One source of updated, risk-stratified treatment are the Mayo Clinic Stratification for Myeloma And Risk-adapted Therapy (mSMART) guidelines:
http://www. Msmart. Org/msmart_mar09_002.htm
Treatment depends on disease (MM) and host (patient) characteristics as well as the goals of therapy. ...Read more

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What is Multiple myeloma a risk factor for?

Multiple issues: It can lead to anemia, increased calcium, renal failure, bone pain and fractures to name a few ...Read more

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How does multiple myeloma affect the kidney?

How does multiple myeloma affect the kidney?

Nephropathy: Myeloma produces proteins called light chains which can essentially "clog up" the kidney producing myeloma nephropathy. Myeloma also produces humoral substances which can damage the kidney. ...Read more

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What is the symptoms for multiple myeloma?

Many symptoms: There may be no symptoms in some people who are found to have myeloma on routine blood tests. Common symptoms include back pain, fatigue, bone fractures. Nausea and vomiting can occur related to kidney or electrolyte problems. ...Read more

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Does personalized medicine apply to diagnosis of typical conditions like multiple myeloma? What tests are needed?

Absolutely: Yes, absolutely.
Molecular analysis with different methods are done to find some specific molecular markers/genes abnormality-
this can be obtained from bone marrow and peripheral blood. This helps us in prognostication as well as in selecting medication. ...Read more

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In peripheral neuropathy with thalidomide, is lenalidomide a good alternative for newly diagnosed multiple myeloma with velcade (bortezomib) dexamethasone?

Possibly: Even though Lenalidomide causes less neuropathy it still occurs. Also depends on the disease. Meaning how aggressive does one need to be. Is there kidney dysfunction? Is the patient of transplant age? ...Read more

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How can the presence of multiple myeloma be recognized in teenagers?

How can the presence of multiple myeloma be recognized in teenagers?

Disease of adults: Multiple myeloma is not a very common disease. It accounts for approximately 1% of all cancers
multiple myeloma is a disease of older adults. The median age at diagnosis is 66 years; only 10 and 2 % of patients are younger than 50 and 40 years, respectively. It is not a disease of teenager. ...Read more

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M57, which is the simple cheapest test for ruling out multiple myeloma first hand when person is in doubt like having pain mild pain in bones. Thanks?

M57, which is the simple cheapest test for ruling out multiple myeloma first hand when person is in doubt like having pain mild pain in bones. Thanks?

Good but tough: Question. To rule in the diagnosis need a bone marrow aspiration and sophisticated protein testing of blood and urine. None of those are cheap. A more cost effective approach eliminating tests would only "partially" rule out the diagnosis of mm ie something could be missed. ...Read more

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What other tests for multiple myeloma?

Blood/Urine/Imaging: Usually workup involves blood and urine tests (spep / upep - serum and urine protein electrophoresis). The preferred initial imaging study is the skeletal survey (x-ray of multiple sites of the body including skull, axial skeleton, and proximal long bones). Bony lesions are usually lytic. ...Read more

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Which groups are most frequently affected by multiple myeloma?

Blacks in US: Twice the incidence in african americans than caucasians. Some families have a higher incidence. ...Read more

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Dr. Creighton Wright
125 Doctors shared insights

Kahler Disease (Definition)

I had not heard of "kahler's disease" until seeing multiple questions on healthtap. It is multiple myeloma (mm). "multiple" is from the often seen "multiple" bone lesions (especially in advanced disease). Mm is a cancer of plasma cells [highly specialized b white blood cells (lymphocytes)] that produce antibodies. Sx are crab: hypercalcemia, renal insufficency, anemia, ...Read more