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Doctor insights on: Multiple Myeloma

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Dr. Liawaty Ho
753 Doctors shared insights

Multiple Myeloma (Overview)

A cancer of the plasma cells, which are responsible for producing antibodies for your body. Symptoms include kidney insufficiency, anemia, bone disease, infections, and pain.


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What other tests for multiple myeloma?

What other tests for multiple myeloma?

Blood/Urine/Imaging: Usually workup involves blood and urine tests (spep / upep - serum and urine protein electrophoresis). The preferred initial imaging study is the skeletal survey (x-ray of multiple sites of the body including skull, axial skeleton, and proximal long bones). Bony lesions are usually lytic. ...Read more

Dr. Liawaty Ho
753 Doctors shared insights

Multiple Myeloma (Overview)

A cancer of the plasma cells, which are responsible for producing antibodies for your body. Symptoms include kidney insufficiency, anemia, bone disease, infections, and pain.


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What is the symptoms for multiple myeloma?

What is the symptoms for multiple myeloma?

Many symptoms: There may be no symptoms in some people who are found to have myeloma on routine blood tests. Common symptoms include back pain, fatigue, bone fractures. Nausea and vomiting can occur related to kidney or electrolyte problems. ...Read more

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Living with Multiple Sclerosis (Checklist)

Prevent falls in the home by removing throw rugs and adding grab bars
Once
Stay cool to avoid becoming overheated
Once
Drink plenty of water
Once
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What are your treatment options for multiple myeloma?

What are your treatment options for multiple myeloma?

Many: There are many options. One source of updated, risk-stratified treatment are the Mayo Clinic Stratification for Myeloma And Risk-adapted Therapy (mSMART) guidelines:
http://www. Msmart. Org/msmart_mar09_002.htm
Treatment depends on disease (MM) and host (patient) characteristics as well as the goals of therapy. ...Read more

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What is Multiple myeloma a risk factor for?

Multiple issues: It can lead to anemia, increased calcium, renal failure, bone pain and fractures to name a few ...Read more

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Living with Addison's Disease (Checklist)

Wear a medic alert
Once
Take additional hydrocortisone/prednisone for fever or injury
Once
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How does multiple myeloma affect the kidney?

How does multiple myeloma affect the kidney?

Nephropathy: Myeloma produces proteins called light chains which can essentially "clog up" the kidney producing myeloma nephropathy. Myeloma also produces humoral substances which can damage the kidney. ...Read more

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What is the symptoms for multiple myeloma?

Many symptoms: There may be no symptoms in some people who are found to have myeloma on routine blood tests. Common symptoms include back pain, fatigue, bone fractures. Nausea and vomiting can occur related to kidney or electrolyte problems. ...Read more

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Does personalized medicine apply to diagnosis of typical conditions like multiple myeloma? What tests are needed?

Absolutely: Yes, absolutely.
Molecular analysis with different methods are done to find some specific molecular markers/genes abnormality-
this can be obtained from bone marrow and peripheral blood. This helps us in prognostication as well as in selecting medication. ...Read more

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Managing Peripheral Vascular Disease (Checklist)

Try to continue walking
Once
Make sure that your risk factors, such as blood pressure and cholesterol, are addressed
Once
Inspect your feet daily, and call your medical doctor if you experience any wounds
Daily
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In peripheral neuropathy with thalidomide, is lenalidomide a good alternative for newly diagnosed multiple myeloma with velcade (bortezomib) dexamethasone?

Possibly: Even though Lenalidomide causes less neuropathy it still occurs. Also depends on the disease. Meaning how aggressive does one need to be. Is there kidney dysfunction? Is the patient of transplant age? ...Read more

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How can the presence of multiple myeloma be recognized in teenagers?

How can the presence of multiple myeloma be recognized in teenagers?

Disease of adults: Multiple myeloma is not a very common disease. It accounts for approximately 1% of all cancers
multiple myeloma is a disease of older adults. The median age at diagnosis is 66 years; only 10 and 2 % of patients are younger than 50 and 40 years, respectively. It is not a disease of teenager. ...Read more

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M57, which is the simple cheapest test for ruling out multiple myeloma first hand when person is in doubt like having pain mild pain in bones. Thanks?

M57, which is the simple cheapest test for ruling out multiple myeloma first hand when person is in doubt like having pain mild pain in bones. Thanks?

Good but tough: Question. To rule in the diagnosis need a bone marrow aspiration and sophisticated protein testing of blood and urine. None of those are cheap. A more cost effective approach eliminating tests would only "partially" rule out the diagnosis of mm ie something could be missed. ...Read more

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What other tests for multiple myeloma?

Blood/Urine/Imaging: Usually workup involves blood and urine tests (spep / upep - serum and urine protein electrophoresis). The preferred initial imaging study is the skeletal survey (x-ray of multiple sites of the body including skull, axial skeleton, and proximal long bones). Bony lesions are usually lytic. ...Read more

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Living with Polycystic Kidney Disease (Checklist)

Reduce stress in your life: Stress causes cysts to grow faster
daily
Adequate daily fluid intake is a requirement for all patients with PKD
daily
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Which groups are most frequently affected by multiple myeloma?

Blacks in US: Twice the incidence in african americans than caucasians. Some families have a higher incidence. ...Read more

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Coping with Disease Outbreaks (Checklist)

Wash hands
6x day
Cover nose and mouth
daily
Avoid unnecessary contact
daily
Alert providers of contagion
daily
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Can radiations from lcd screen of computer cause multiple myeloma?

No: No. There is no evidence nor any plausible biological reason to think that lcd screens cause myeloma or any other type of cancer. ...Read more

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My sister was diagnosed with multiple myeloma idg. What does this mean?

Plasma cell cancer: From the National Cancer Institute --> What You Need To Know Aboutâ„¢ - What is Multiple #Myeloma - via @theNCI http://ow. Ly/o7CJR #mmsm and Snapshot: http://ow. Ly/ungNs

The IgG is the type of immunoglobulin heavy chain involved and can be used to follow the cancer in the blood. ...Read more

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Treating Pelvic Inflammatory Disease (Checklist)

Ask your doctor for further STD testing
Once
Ask your partner to get tested for STDs
Once
Take all of your medication exactly as prescribed
Once
Use condoms when having intercourse to prevent STD transmission
Once
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Can doxil (liposomal doxorubicin) treat multiple myeloma?

Yes: Yes, Doxil (liposomal doxorubicin) can be used to treat multiple myeloma. Discuss further in detail with your oncologist -whether the chemotherapy would be appropriate for your case. ...Read more

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Living with Coronary Artery Disease (Checklist)

Take medications as prescribed
Once
Exercise daily as recommended by your doctor or trainer
daily
Limit meat, dairy, and fats as much as possible
Once
Eat whole grains only - not white bread
Once
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What is the objective of treating multiple myeloma?

Depends...: This answer depends. That might not be as satisfying but is true. For a 90yo pt it is palliative -- keeping crab symptoms away with minimal discomfort fro m tx. A new study from dr. Campagnaro in ecog will evaluate. For most, "control" as a chronic disease. For some cure. If young, we like to obtain a "deep" response w/ complete response (cr) & now looking at minimal residual disease (mrd) by flow. ...Read more

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What types of questions should I ask my doctor regarding treatment for multiple myeloma or other plasma cell cancer?

What types of questions should I ask my doctor regarding treatment for multiple myeloma or other plasma cell cancer?

1-2-3: Cancer 1-2-3:
1) diagnosis - myeloma vs.?
2a) stage - iss (not that relevant for individual)
2b) prognostic factors - eg cytogenetics, pcli (if avail), gep (new), bone disease, etc.
3) treatment -- goals (response or quality or....) and options. Some regiments are easy eg rd which is good for a low burden mm disease and working pt vs. More complicated "induction" regimen for high risk/burden. ...Read more

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Living with Sickle Cell Disease (Checklist)

Don't miss appointments with your doctor
Once
Go to lab appointments as necessary
Once
Keep your oxygen levels up by maintaining a healthy weight
Once
Dr. Debra Rosenblatt
125 Doctors shared insights

Kahler Disease (Definition)

I had not heard of "kahler's disease" until seeing multiple questions on healthtap. It is multiple myeloma (mm). "multiple" is from the often seen "multiple" bone lesions (especially in advanced disease). Mm is a cancer of plasma cells [highly specialized b white blood cells (lymphocytes)] that produce antibodies. Sx are crab: hypercalcemia, renal insufficency, anemia, ...Read more