Doctor insights on:
Multiple Endocrine Neoplasia In Children
Labs and Imaging: There are many lab studies as well as imaging evaluation of the organs involved. Serum calcium, parathyroid hormone levels, calcitonin, cea, pituitary hormones, pancreatic hormones (including insulin, glucagon, etc), and a variety of adrenal hormones (epinephrine, norepinephrine, metanephrines, dopa, and their metabolites). A full evaluation requires extensive testing, including stimulation tests. Read moreSee 1 more doctor answer
Multiple endocrine neoplasia (MEN) syndromes are rare, inherited disorders in which several endocrine glands develop noncancerous (benign) or cancerous (malignant) tumors or grow excessively without forming tumors. The major forms are MEN type 1 or type 2 (2A and 2B). These types are distinguished by the genes involved, the types of hormones made, and the ...Read more
Depends on Organ: They cover so many organs because pituitary, parathyroid, thyroid, pancreas and adrenal glands can all be affected. The symptoms are usually non-specific, such as fatigue, weight loss, tremor, visual changes, heart irregularities, diarrhea, high blood presssure, etc. There are too many to list here -- but usually additional testing is required to document this uncommon disease group. Read more
MEN Syndromes: Multiple endocrine neoplasia (MEN) syndromes are rare, inherited disorders in which several endocrine glands develop noncancerous (benign) or cancerous (malignant) tumors or grow excessively without forming tumors. The major forms are MEN type 1 or type 2 (2A and 2B). These types are distinguished by the genes involved, the types of hormones made, and the characteristic signs and symptoms. Read more
Surgery usually: It depends what type (men1, 2a or 2b) you have. While hormone manipulation for parathyroid, calcium, and glucose can manage some symptoms, and hypertension can be managed with medication -- all of these "tumors" need to be removed to completely manage the disease. Generally, the pancreatic, adrenal and thyroid tumors are more troublesome than the parathyroid or pituitary. Read more
Menin, MEN1 gene: Hi. MEN1 is inherited in an autosomal-dominant fashion, so you only need one mutant (bad) copy of the gene to have the MEN1 syndrome. You have one bad copy one good copy of the MEN1 gene, and due to random assortment in meiosis, your baby has a 50/50 chance of getting your bad MEN1 gene (and a 50/50 chance of getting your GOOD MEN1 gene). Prenatal genetic testing IS available. Read more
Yes: Hyperparathyroidism due to over active parathyroid glands causes high blood calcium levels in those with men1. This can be managed by removing the parathyroid glands and reimplanting part of the smallest gland in your forearm muscle. Your calcium levels should then normalize. Read moreSee 1 more doctor answer
24 y/o, frequent heartburn, pituitary macro prolactinoma, (being treated), fatigue calcium level 10.1 could it be multiple endocrine neoplasia type 1?
Calcium 10.1 is normal. Then you are asking if somebody has prolactinoma, what is the chance of men type 1? Very low possibility since prolactinoma is not common and men is a rare disease.
Fatigue is very non-specific finding that can be seen in diverse types of condition or disease. Plz talk to pcp. Read more
For a 29 yo female, no children, with 4 recent episodes of 5-10 day acute confusion psychosis since december (no history) req hospitalisation, as well as 4 month amenorrhea is endocrine disorder pos?
Both: It is an endocrine disorder that has an autoimmune cause. Read more
We don't know: Endocrine disruptors have become a hot topic within the past several years. There are many endocrine disruptors (and some we don't know about yet most likely), some ingested, some which can be absorbed through the skin. There's a matter of chronic vs short term exposure. It will probably be many years before we know which endocrine disruptors hang around for long periods of time/forever. Read more
So called: Endocrine interrupters is an internet hoax about contaminants in waste water. It has no scientific backing whatsoever. Don't get your medical information from friends, tv or the internet scams. Read more
A good question.
Please go online and search for articles about the endocrine system but search only for articles designed for folks who have not joined any class to understand the different components.
You should find several articles specifically designed to help you understand.
Please let me know how this works out. Read more
Low thyroid bad: Low thyroid can be very, very serious, even fatal when it entirely fails. Thankfully it usually doesn't stop entirely and we have replacement hormones so we rarely see life-threating thyroid disease. Raynaud's can be triggered by stress but most often by cold. Low thyroid often makes people cold and also causes stress. Read more
Hormones: An endocrine disorder is disorder of the endocrine glands which are typically responsible for hormones production/release and regulation. Some examples of endocrine disorders are: disorders of the thyroid, adrenal, pituitary, reproductive system, parathyroid, bone. Read moreSee 1 more doctor answer
Great question!: Endocrine glands (thyroid, adrenal, and pituitary glands, among many others) produce hormones. A hormone is a molecule which is released into the blood to travel to other cells. When the hormone meets a receptor molecule in these other cells, the hormone can change the activity of that cell. For example, Insulin is a hormone which promotes the uptake of glucose in other cells in the body. Read moreSee 1 more doctor answer
Never mess with: Mother Nature just to try to ^ a healthy kid's adult height. When pediatricians & family medicine doctors suspect Precocious Puberty &/or short stature, they obtain a medical & developmental history, perform physical & neurological exams, order bone age films & labs for genetic & endocrine causes & refer to a pediatric endocrinologist &/or geneticist depending on the results of their evaluation. Read more
"tumor" literally translates as "mass", so even a fresh bruise could be called a "tumor". Doctors use the term "neoplasm" (tranlates literally as new growth) to describe tumors that are abnormal growths of cells. These may be benign or malignant; "malignant" = cancer. In everyday usage, we use "tumor" ...Read more