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Doctor insights on: Multiple Endocrine Neoplasia

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Dr. Cynthia Lu
76 doctors shared insights

Multiple Endocrine Neoplasia (Overview)

Multiple endocrine neoplasia (MEN) syndromes are rare, inherited disorders in which several endocrine glands develop noncancerous (benign) or cancerous (malignant) tumors or grow excessively without forming tumors. The major forms are MEN type 1 or type 2 (2A and 2B). These types are distinguished by the genes involved, the types of hormones made, and the characteristic signs and symptoms.


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What things make multiple endocrine neoplasia more likely?

What things make multiple endocrine neoplasia more likely?

Family history: Men (multiple endocrine neoplasia) syndromes are genetically passed through families. A person with one of these syndromes has a 50% chance of passing it to a child. ...Read more

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Dr. Cynthia Lu
76 doctors shared insights

Multiple Endocrine Neoplasia (Overview)

Multiple endocrine neoplasia (MEN) syndromes are rare, inherited disorders in which several endocrine glands develop noncancerous (benign) or cancerous (malignant) tumors or grow excessively without forming tumors. The major forms are MEN type 1 or type 2 (2A and 2B). These types are distinguished by the genes involved, the types of hormones made, and the characteristic signs and symptoms.


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What are the common symptoms of multiple endocrine neoplasia?

Depends on Organ: They cover so many organs because pituitary, parathyroid, thyroid, pancreas and adrenal glands can all be affected. The symptoms are usually non-specific, such as fatigue, weight loss, tremor, visual changes, heart irregularities, diarrhea, high blood presssure, etc. There are too many to list here -- but usually additional testing is required to document this uncommon disease group. ...Read more

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Living with Multiple Sclerosis (Checklist)

Prevent falls in the home by removing throw rugs, adding grab bars
Once
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Drink plenty of water
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What are the tests for multiple endocrine neoplasia?

Labs and Imaging: There are many lab studies as well as imaging evaluation of the organs involved. Serum calcium, parathyroid hormone levels, calcitonin, cea, pituitary hormones, pancreatic hormones (including insulin, glucagon, etc), and a variety of adrenal hormones (epinephrine, norepinephrine, metanephrines, dopa, and their metabolites). A full evaluation requires extensive testing, including stimulation tests. ...Read more

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What to do if I have multiple endocrine neoplasia type 1 and I am pregnant what now?

What to do if I have multiple endocrine neoplasia type 1 and I am pregnant what now?

Menin, MEN1 gene: Hi. MEN1 is inherited in an autosomal-dominant fashion, so you only need one mutant (bad) copy of the gene to have the MEN1 syndrome. You have one bad copy one good copy of the MEN1 gene, and due to random assortment in meiosis, your baby has a 50/50 chance of getting your bad MEN1 gene (and a 50/50 chance of getting your GOOD MEN1 gene). Prenatal genetic testing IS available. ...Read more

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24 y/o, frequent heartburn, pituitary macro prolactinoma, (being treated), fatigue calcium level 10.1 could it be multiple endocrine neoplasia type 1?

Need Clarification: Calcium 10.1 is normal. Then you are asking if somebody has prolactinoma, what is the chance of men type 1? Very low possibility since prolactinoma is not common and men is a rare disease. Fatigue is very non-specific finding that can be seen in diverse types of condition or disease. Plz talk to pcp. ...Read more

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What is the treatment for multiple endocrine neoplasia?

Surgery usually: It depends what type (men1, 2a or 2b) you have. While hormone manipulation for parathyroid, calcium, and glucose can manage some symptoms, and hypertension can be managed with medication -- all of these "tumors" need to be removed to completely manage the disease. Generally, the pancreatic, adrenal and thyroid tumors are more troublesome than the parathyroid or pituitary. ...Read more

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What are the tests for multiple endocrine neoplasia?

Labs and Imaging: There are many lab studies as well as imaging evaluation of the organs involved. Serum calcium, parathyroid hormone levels, calcitonin, cea, pituitary hormones, pancreatic hormones (including insulin, glucagon, etc), and a variety of adrenal hormones (epinephrine, norepinephrine, metanephrines, dopa, and their metabolites). A full evaluation requires extensive testing, including stimulation tests. ...Read more

See 1 more doctor answer
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9
What things make multiple endocrine neoplasia more likely?

Family history: Men (multiple endocrine neoplasia) syndromes are genetically passed through families. A person with one of these syndromes has a 50% chance of passing it to a child. ...Read more

See 1 more doctor answer
10

10
What are the common symptoms of multiple endocrine neoplasia?

Depends on Organ: They cover so many organs because pituitary, parathyroid, thyroid, pancreas and adrenal glands can all be affected. The symptoms are usually non-specific, such as fatigue, weight loss, tremor, visual changes, heart irregularities, diarrhea, high blood presssure, etc. There are too many to list here -- but usually additional testing is required to document this uncommon disease group. ...Read more

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What is the definition or description of: Multiple endocrine neoplasia?

What is the definition or description of: Multiple endocrine neoplasia?

MEN Syndromes: Multiple endocrine neoplasia (MEN) syndromes are rare, inherited disorders in which several endocrine glands develop noncancerous (benign) or cancerous (malignant) tumors or grow excessively without forming tumors. The major forms are MEN type 1 or type 2 (2A and 2B). These types are distinguished by the genes involved, the types of hormones made, and the characteristic signs and symptoms. ...Read more

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What is the treatment for multiple endocrine neoplasia?

Surgery usually: It depends what type (men1, 2a or 2b) you have. While hormone manipulation for parathyroid, calcium, and glucose can manage some symptoms, and hypertension can be managed with medication -- all of these "tumors" need to be removed to completely manage the disease. Generally, the pancreatic, adrenal and thyroid tumors are more troublesome than the parathyroid or pituitary. ...Read more

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13
What to do if I have multiple endocrine neoplasia type 1 and I am pregnant what now?

Menin, MEN1 gene: Hi. MEN1 is inherited in an autosomal-dominant fashion, so you only need one mutant (bad) copy of the gene to have the MEN1 syndrome. You have one bad copy one good copy of the MEN1 gene, and due to random assortment in meiosis, your baby has a 50/50 chance of getting your bad MEN1 gene (and a 50/50 chance of getting your GOOD MEN1 gene). Prenatal genetic testing IS available. ...Read more

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Does multiple endocrine neoplasia type 1 present with high blood calcium? Mine is 10.1 thank you!

Does multiple endocrine neoplasia type 1 present with high blood calcium? Mine is 10.1   thank you!

Yes: Hyperparathyroidism due to over active parathyroid glands causes high blood calcium levels in those with men1. This can be managed by removing the parathyroid glands and reimplanting part of the smallest gland in your forearm muscle. Your calcium levels should then normalize. ...Read more

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24 y/o, frequent heartburn, pituitary macro prolactinoma, (being treated), fatigue calcium level 10.1 could it be multiple endocrine neoplasia type 1?

Need Clarification: Calcium 10.1 is normal. Then you are asking if somebody has prolactinoma, what is the chance of men type 1? Very low possibility since prolactinoma is not common and men is a rare disease. Fatigue is very non-specific finding that can be seen in diverse types of condition or disease. Plz talk to pcp. ...Read more

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What is an endocrine study? How is it done?

Need more info: Without information as to why an endocrine study was recommended for you, i cannot give you an answer, except to say that most endocrine testing is done through taking a blood sample. ...Read more

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What is endocrine disorder?

What is endocrine disorder?

Hormones: An endocrine disorder is disorder of the endocrine glands which are typically responsible for hormones production/release and regulation. Some examples of endocrine disorders are: disorders of the thyroid, adrenal, pituitary, reproductive system, parathyroid, bone. ...Read more

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What are the endocrine glands for?

Great question!: Endocrine glands (thyroid, adrenal, and pituitary glands, among many others) produce hormones. A hormone is a molecule which is released into the blood to travel to other cells. When the hormone meets a receptor molecule in these other cells, the hormone can change the activity of that cell. For example, Insulin is a hormone which promotes the uptake of glucose in other cells in the body. ...Read more

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Does botox affect the endocrine system?

Does botox affect the endocrine system?

No : Botox is a muscle blocker. It stops muscles from working thereby lessening wrinkles. ...Read more

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Neoplasms (Definition)

"tumor" literally translates as "mass", so even a fresh bruise could be called a "tumor". Doctors use the term "neoplasm" (tranlates literally as new growth) to describe tumors that are abnormal growths of cells. These may be benign or malignant; "malignant" = cancer. In everyday usage, we use "tumor" ...Read more


Dr. Tyrone Malloy
246 doctors shared insights

Endocrine System (Definition)

The endocrine system is a group of organs composed of glands that secrete hormones. These hormones have important regulatory functions such as growth, metabolism, ...Read more