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Doctor insights on: Multiple Endocrine Neoplasia

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Dr. Cynthia Lu
75 doctors shared insights

Multiple Endocrine Neoplasia (Overview)

Multiple endocrine neoplasia is a condition where patients have abnormal growths in several endocrine (hormone producing) organs.


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What things make multiple endocrine neoplasia more likely?

What things make multiple endocrine neoplasia more likely?

Family history: Men (multiple endocrine neoplasia) syndromes are genetically passed through families. A person with one of these syndromes has a 50% chance of passing it to a child. ...Read more

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Dr. Cynthia Lu
75 doctors shared insights

Multiple Endocrine Neoplasia (Overview)

Multiple endocrine neoplasia is a condition where patients have abnormal growths in several endocrine (hormone producing) organs.


2

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What are the common symptoms of multiple endocrine neoplasia?

Depends on Organ: They cover so many organs because pituitary, parathyroid, thyroid, pancreas and adrenal glands can all be affected. The symptoms are usually non-specific, such as fatigue, weight loss, tremor, visual changes, heart irregularities, diarrhea, high blood presssure, etc. There are too many to list here -- but usually additional testing is required to document this uncommon disease group. ...Read more

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Living with Multiple Sclerosis (Checklist)

Prevent falls in the home by removing throw rugs, adding grab bars
Once
Stay cool, avoid being overheated
Once
Drink plenty of water
Once
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What are the tests for multiple endocrine neoplasia?

Labs and Imaging: There are many lab studies as well as imaging evaluation of the organs involved. Serum calcium, parathyroid hormone levels, calcitonin, cea, pituitary hormones, pancreatic hormones (including insulin, glucagon, etc), and a variety of adrenal hormones (epinephrine, norepinephrine, metanephrines, dopa, and their metabolites). A full evaluation requires extensive testing, including stimulation tests. ...Read more

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What to do if I have multiple endocrine neoplasia type 1 and I am pregnant what now?

What to do if I have multiple endocrine neoplasia type 1 and I am pregnant what now?

Menin, MEN1 gene: Hi. MEN1 is inherited in an autosomal-dominant fashion, so you only need one mutant (bad) copy of the gene to have the MEN1 syndrome. You have one bad copy one good copy of the MEN1 gene, and due to random assortment in meiosis, your baby has a 50/50 chance of getting your bad MEN1 gene (and a 50/50 chance of getting your GOOD MEN1 gene). Prenatal genetic testing IS available. ...Read more

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24 y/o, frequent heartburn, pituitary macro prolactinoma, (being treated), fatigue calcium level 10.1 could it be multiple endocrine neoplasia type 1?

Need Clarification: Calcium 10.1 is normal. Then you are asking if somebody has prolactinoma, what is the chance of men type 1? Very low possibility since prolactinoma is not common and men is a rare disease. Fatigue is very non-specific finding that can be seen in diverse types of condition or disease. Plz talk to pcp. ...Read more

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What is the treatment for multiple endocrine neoplasia?

Surgery usually: It depends what type (men1, 2a or 2b) you have. While hormone manipulation for parathyroid, calcium, and glucose can manage some symptoms, and hypertension can be managed with medication -- all of these "tumors" need to be removed to completely manage the disease. Generally, the pancreatic, adrenal and thyroid tumors are more troublesome than the parathyroid or pituitary. ...Read more

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What are the tests for multiple endocrine neoplasia?

Labs and Imaging: There are many lab studies as well as imaging evaluation of the organs involved. Serum calcium, parathyroid hormone levels, calcitonin, cea, pituitary hormones, pancreatic hormones (including insulin, glucagon, etc), and a variety of adrenal hormones (epinephrine, norepinephrine, metanephrines, dopa, and their metabolites). A full evaluation requires extensive testing, including stimulation tests. ...Read more

See 1 more doctor answer
9

9
What things make multiple endocrine neoplasia more likely?

Family history: Men (multiple endocrine neoplasia) syndromes are genetically passed through families. A person with one of these syndromes has a 50% chance of passing it to a child. ...Read more

See 1 more doctor answer
10

10
What are the common symptoms of multiple endocrine neoplasia?

Depends on Organ: They cover so many organs because pituitary, parathyroid, thyroid, pancreas and adrenal glands can all be affected. The symptoms are usually non-specific, such as fatigue, weight loss, tremor, visual changes, heart irregularities, diarrhea, high blood presssure, etc. There are too many to list here -- but usually additional testing is required to document this uncommon disease group. ...Read more

Neoplasms (Definition)

"tumor" literally translates as "mass", so even a fresh bruise could be called a "tumor". Doctors use the term "neoplasm" (tranlates literally as new growth) to describe tumors that are abnormal growths of cells. These may be benign or malignant; "malignant" = cancer. In everyday usage, we use "tumor" ...Read more


Dr. Tyrone Malloy
228 doctors shared insights

Endocrine System (Definition)

The endocrine system is a group of organs composed of glands that secrete hormones. These hormones have important regulatory functions such as growth, metabolism, ...Read more