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Doctor insights on: Multiple Alleles

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What is an allele?

What is an allele?

Genetics: An allele is a viable dna (deoxyribonucleic acid) coding that occupies a given position (locus) on a chromosome. Usually alleles are sequences that code for a gene. ...Read more

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What are alleles functions?

Copies of genes: Every gene in your genome has two copies (or should), and the individual copies are called "alleles". The differences between alleles can reflect the different inheritance from your two parents and explains why people aren't identical copies of their parents. So these differences provide genetic diversity. ...Read more

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Is it possible for a person to have two dominate alleles for huntingtons?

Is it possible for a person to have two dominate alleles for huntingtons?

Yes: It's very unusual for someone to inherit two mutations - one for each of their huntington disease genes, but it's possible. A person with homozygosity will develop the signs and symptoms of hd at about the same age, on average, as someone with just one mutation. However, the disease progresses more rapidly. Here is a link to some research: http://www.Ncbi.Nlm.Nih.Gov/pubmed/12615650. ...Read more

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How common is it to have one allele in the normal range and one allele in the mutable range, for huntingtons?

How common is it to have one allele in the normal range and one allele in the mutable range, for huntingtons?

Not rare for some: In families with huntington's, only one allele need be abnormal for the disease to manifest, that is what it means that it is an "autosomal dominant" disease. If you have been tested, you should have access to a genetic counselor, and that is with whom you should discuss your results. This is an important issue for you, and you should get the best possible full explanations, not this website's. ...Read more

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Can you mix allele with hydrocodone acetiminofin?

Can you mix allele with hydrocodone acetiminofin?

Misspelled: Allele refers to genetic expression of genes that can effect metabolism of drugs. Please resubmit question with correct drug spelling of the drug interaction you are concerned with. ...Read more

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Is dwarfism caused by a recessive or dominant allele?

Is dwarfism caused by a recessive or dominant allele?

It depends: It depends on what one means by dwarfism: a short stature in general (this depends on your ethnic origin as well) or a genetic syndrome which involves extremely short stature as part of the clinical picture. Some of them are dominant = inherited from a parent or rose spontaneously (de novo) in the individual. Some of them are recessive (=parents unaffected carriers of the condition). ...Read more

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What exactly is the cause of lou gehrig's disease: a dominant allele or a recessive one?

What exactly is the cause of lou gehrig's disease: a dominant allele or a recessive one?

Neither: Familial ALS is relatively uncommon, especially in view of fact that this is a rather rare disease. Over 90% are sporadic, without clearcut genetic answers. ...Read more

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Hi I am 18 an just got tested for huntington's disease. Can someone please explain what ( allele 1: w/ 31 cag and allele 2: w/ 15 cag repeats means?

Talk with doc: You really should speak with the person who ordered the test to get the final interpretation. In general, huntington's disease (hd) is caused by an expansion of cag repeats. The range of repeat length in the unaffected population is 6–35 repeats. We have two copies, or alleles, of the gene. Both of your alleles are in the normal range, thus no hd. Once again, speak with your doc for final word. ...Read more