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Doctor insights on: Mthfr Deficiency Pregnancy

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Does mthfr heterozygous c677t mutation affect pregnancy?

Does mthfr heterozygous c677t mutation affect pregnancy?

Likely not much: The existing evidence does not support any strong connection between heterozygotes for either the c or a mutations of mthfr and poor pregnancy outcomes. Homozygotes may well be at greater risk. Depending on clinical history, different levels or surveillance and possible intervention can be considered. ...Read more

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Dr. Dariush Saghafi
4 Doctors shared insights

Pregnancy (Definition)

When your due date arrives, you will be more than ready to have your baby! Most women deliver the baby somewhere between 37 and 42 weeks. According to the American College of Obstetricians and Gynecologists, only 5% of babies arrive on the exact due date. Approximately 7% of babies are not delivered by 42 weeks, and when that happens, it is referred to ...Read more


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Found out I have MTHFR homozygous 1298. Had one successful pregnancy before I ever knew, but worried about future pregnancies. Precautions to take?

Found out I have MTHFR homozygous 1298. Had one successful pregnancy before I ever knew, but worried about future pregnancies. Precautions to take?

Genetic questions: The best place to start when considering family planning in the context of a known mutation is to sit down with a genetics counselor. There are many facets to this conversation that should be discussed at one time for purposes of both safety and of reassurance. Please consider this first step. ...Read more

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Can you please define mthfr deficiency?

Can you please define mthfr deficiency?

Methylfolate: MTHFR is a gene that codes for an enzyme that makes methylfolate. Mutation can cause decreased enzymatic function resulting in less methylfolate being produced. Not everyone who has MTHFR needs to supplement methylfolate. Those who eat plenty of raw fruit and vegetables may get adequate methylfolate from their diet. ...Read more

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What to do if I have a successful pregnancy with mthfr?

MTHFR: Avoid unmethylated forms of vitamin B12 and folate (folic acid). Instead, use methylcobalamin and methylfolate (folic acid). Also, eat dark leafy greens, uncooked, twice a day. Work with a doctor who is well versed with MTHFR SNPs. You can check www. Mthfr. Net for a list of doctors trained in this. ...Read more

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What can I do to increase chance of a successful pregnancy with PAI and MTHFR?

What can I do to increase chance of a successful pregnancy with PAI and MTHFR?

MTHFR: For MTHFR, you want to avoid synthetic folic acid, and take folinic acid and methylfolate instead. More into on: Http://drfairchild. Blogspot. Com/2013/10/mthfr. Html ...Read more

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3 miscarriages and a&c mthfr should I be on lovenox (enoxaparin) or heparin on next pregnancy?

3 miscarriages and a&c mthfr should I be on lovenox (enoxaparin) or heparin on next pregnancy?

Discuss with doctor: Not sure what a&c means. Mthfr mutation is very weakly associated with miscarriage. If you are heterozygous then blood thinning medicines are not indicated. If you are homozygous then possibly. Ask about a fasting homocystine test. Your age of 41 is also a risk factor for miscarriage. ...Read more

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I have had thermal ablation and also have mthfr, is it possible for me to carry a pregnancy to term?

I have had thermal ablation and also have mthfr, is it possible for me to carry a pregnancy to term?

Unsure: The mthfr should not really matter. Unless you homocysteine is elevated mthfr does not affect anything at all. It is very difficult to become pregnant after a thermal ablation and requires a fertility specialist to investigate and test the uterus to see if pregnancy is possible. ...Read more

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Positive mthfr heterozygous after multiple miscarriages, known pernicious anemia, what is the likelihood of having other b vitamin deficiencies?

Positive mthfr heterozygous after multiple miscarriages, known pernicious anemia, what is the likelihood of having other b vitamin deficiencies?

Not more likely but: Pernicious anemia is due to problems absorbing B12 but doesn't interfere with absorbing other vits. Mthfr mutations mean you have trouble converting Folic Acid to the active form, so take l-5-mthf. Genes don't affect absorption of other b vits but due to genetics some require higher amounts of b's than others-your other issues don't mean you're more likely to have this but it's safe to try b complex. ...Read more

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I have a mutation of the mthfr gene and have had a thermal ablation. I have had 4 pregnancies and lost them. Uterine lining is 3.74 can I carry a baby?

I have a mutation of the mthfr gene and have had a thermal ablation. I have had 4 pregnancies and lost them. Uterine lining is 3.74 can I carry a baby?

MTHFR Gene mutation: Here's some important information on the mthfr gene mutation... http://doccarnahan. Blogspot. Com/2013/10/whats-big-deal-about-methylation-update. Html. ...Read more

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Does heterozygous for MTHFR gene mutation affect pregnancy?, and what about taking synthetic folic acid supplement?

Does heterozygous for MTHFR gene mutation affect pregnancy?, and what about taking synthetic folic acid supplement?

Controversial...: Some studies have shown an association between the MTHFR gene mutation and recurrent miscarriages but this is controversial. Aside from this possibility, it doesn't cause problems with pregnancy. If you have this mutation, its a good idea to take folic acid, vitamin B-12 and Vitamen B-6. Aspirin is also sometimes recommended for women for who have had recurrent miscarriages. Best wishes! ...Read more

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Does mthfr cause miscarriage? I know I need to increase my folic acid but some dr's prescribe aspirin for pregnancy. My dr says no

Does mthfr cause miscarriage? I know I need to increase my folic acid but some dr's prescribe aspirin for pregnancy. My dr says no

Likely, no: New data has shown that a diagnosis of mthfr mutation is not a likely culprit for miscarriage. New recommendations from the american college of ob/gyn state: screening homocysteine levels or (mthfr) is not recommended, b/c mthfr has not been associated with poor pregnancy outcomes. Folic acid is always a good idea in pregnancy. A baby Aspirin for women with unexplained miscarriages, also good. ...Read more

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What diseases are caused by zinc deficiency in pregnancy?

What diseases are caused by zinc deficiency in pregnancy?

Interesting question: Zinc supplementation during pregnancy for women with mild zinc deficiency appears to promote fetal growth and reduce the risk of premature birth and infant diarrhea. Acrodermatitis enteropathica can be seen in pregnant women with severe zinc deficiency. ...Read more

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Can you explain protein c deficiency in pregnancy?

Can you explain protein c deficiency in pregnancy?

See below: Protein c deficiency increases your risk for clot formation. If clots form in the placental vessels, that would compromise blood flow, which could harm the fetus. ...Read more

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How does having a protein s deficiency affect pregnancy?

How does having a protein s deficiency affect pregnancy?

Level decreases: The level decreases in pregnancy. Protein s and protein c are there to decrease the incidence of clots. If the level decreases, then clots can develop. In pregnancy, the level decreases and the chance of a blood clot increases. Hope this helps. ...Read more

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I have factor 7 deficiency and terminated a pregnancy today without telling the doctors about it what could happen to me?

I have factor 7 deficiency and terminated a pregnancy today without telling the doctors about it what could happen to me?

Bleeding: Well you already did it but factor 7 def can cause abnormal bleeding. This is an important thing to share with your surgeon before you have a surgical procedure. If you were going to have problems it would have happened during or immediately after surgery. ...Read more

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I have APS, lupus and adrenal deficiency, would I have a safe pregnancy?

I have APS, lupus and adrenal deficiency, would I have a safe pregnancy?

Depends: Are your conditions under control? Remission? What maintenance medications are you on? Are these safe for pregnancy? How long have you been flare free? What are your titers? Do you have any end organ such as kidney damage?? Best is to discuss first with your rheumatologist, endocrinologist and seek a perinatal specialist opinion. Best Wishes ...Read more

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If your 6 weeks into your pregnancy and have an iron deficiency can you take iron pills and prenatal pills?

If your 6 weeks into your pregnancy and have an iron deficiency can you take iron pills and prenatal pills?

Yes absolutely: Yes, definitely- if you know that you have iron deficiency anemia to begin with in addition taking the prenatal vitamin you should also take iron replacement pills as there is only low dose of iron inside the prenatal vitamin and it is not enough to meet the demand of iron during pregnancy. Enjoy your pregnancy. ...Read more

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Taking a prenatal vitamin with 100% dv of vit d (400 iu) throughout 30w of pregnancy. I don't have symptoms of deficiency. Worry for baby?

Taking a prenatal vitamin with 100% dv of vit d (400 iu) throughout 30w of pregnancy. I don't have symptoms of deficiency. Worry for baby?

Little worry but...: Actually the recommended daily intake of d has been increased to 600 iu/day but most adults need at least 5000 iu/day for optimal levels- see http://bit. Ly/1dc7vna low d increases your risk of diabetes ; preeclampsia ; can result in a baby with low birth weight, but hopefully you are not too deficient. Get levels checked now, take more d ; get sun- see http://bit. Ly/1gnxnk0. ...Read more