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Doctor insights on: Msafp Screening Test

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Dr. Gary Sandler
4 Doctors shared insights

Msafp Screening Test (Overview)

Alpha-fetoprotein (AFP) is a protein that is normally produced by the fetus' liver. AFP is present in the fluid around the fetus (amniotic fluid) and a small amount crosses the placenta and moves into the mother's blood stream. As the baby grows and produces more AFP, the amount in the mother's blood increases. Between weeks 15 and 20 of a pregnancy, a maternal serum alpha-fetoprotein (MSAFP) screen may be offered. It's usually as part of a set of tests, which screen for genetic problems, called the quad screen. The AFP blood test determines how much AFP is in the mother's blood. The other tests measure the levels of other pregnancy hormones, including estriol, human chorionic gonadotropin (HCG), and inhibin A.


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What other brain disorders can the msafp screening identify?

What other brain disorders can the msafp screening identify?

MSAFP: The msafp is a screen for an open neural tube abnormality in the fetus. It identifies spina bifida, which can also cause hydrocephalus. It also is a screen for Down syndrome and trisomy 18, both of which affect the brain. ...Read more

Dr. Gary Sandler
4 Doctors shared insights

Msafp Screening Test (Overview)

Alpha-fetoprotein (AFP) is a protein that is normally produced by the fetus' liver. AFP is present in the fluid around the fetus (amniotic fluid) and a small amount crosses the placenta and moves into the mother's blood stream. As the baby grows and produces more AFP, the amount in the mother's blood increases. Between weeks 15 and 20 of a pregnancy, a maternal serum alpha-fetoprotein (MSAFP) screen may be offered. It's usually as part of a set of tests, which screen for genetic problems, called the quad screen. The AFP blood test determines how much AFP is in the mother's blood. The other tests measure the levels of other pregnancy hormones, including estriol, human chorionic gonadotropin (HCG), and inhibin A.


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What other brain disorders can the msafp screening identify?

MSAFP: The msafp is a screen for an open neural tube abnormality in the fetus. It identifies spina bifida, which can also cause hydrocephalus. It also is a screen for Down syndrome and trisomy 18, both of which affect the brain. ...Read more

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Could you tell me what are psychological screening tests?

Could you tell me what are psychological screening tests?

Many available: There are various tests that measure symptom severity for a variety of diagnoses including depression, several anxiety disorders including ptsd and panic disorder, ocd, add and others. ...Read more

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What do you suggest for eating before glucose screening test?

Nothing: In general this would be a fasting blood test. This is not clearly defined, but lab professionals tell me that you should go at least 8 hours with nothing to eat or drink except water, plain tea or coffee and your medicines. There is also a test called an A1c, or average blood sugar that can be done after eating. For more info on proven screening tests, consider the Prevention Checklist app. ...Read more

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How should I prepare for a drug and alcohol screening/test coming up soon?

How should I prepare for a drug and alcohol screening/test coming up soon?

Depends: I assume you are using drugs since you asked this question. Stop using. Depending on what test (s) they are using, and what drugs you are using, most drugs and their metabolites are out of the body in as little as 3 days. Some drugs, particularly marijuana, may stick around in fat cells for weeks or even a few months. There is no way to flush drugs out of the body, and masking it doesn't work. ...Read more

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What do you think about these new non-invasive screening tests for Down syndrome that have been recently introduced to the market?

What do you think about these new non-invasive screening tests for Down syndrome that have been recently introduced to the market?

Serve no purpose: Your OB is quite capable of deciding if you are at risk, in fact most people who find out the results are positive proceed with the pregnancy, so no real point unless you are able to abort your own child, which most people find hard to do. ...Read more

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Does a negative westernblot for HIV1&2 (as a screening test) @ 16weeks post exposure rule out hiv1&2 100%? Do I need repeat test at 6 months? Thanks!

Does a negative westernblot for HIV1&2 (as a screening test) @ 16weeks post exposure rule out hiv1&2 100%? Do I need repeat test at 6 months? Thanks!

Wrong test, too long: The HIV Western blot test is not intended for screening and could miss some infections. You need a 4th generation (duo, antigen-antibody) test, which is conclusive any time 4 weeks or more after exposure; or a 3rd gen antibody test at least 8 weeks after exposure. Nobody needs testing as long as 6 months; even 3 month is longer than needed with modern tests. Discuss with an NHS GUM clinic. ...Read more

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What are the chances of an abnormality (of any kind) to go undetected in pre natal screening & tests for fetus in today's world? Pls give % & explain

What are the chances of an abnormality (of any kind) to go undetected in pre natal screening & tests for fetus in today's world? Pls give % & explain

Pretty low: The answer depends on who type of prenatal screening you did. There are several different ways to do and each one has a different detections rate. Even the most basic tests detect over 90% of abnormalities. Find out from your doctor what prenatal tests you did. A simple google search of that test should outline the detection rates for your specific method ...Read more

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Hello dr I did a screening test for safety of baby the test was negative but they writ that it will have a risk 1/25 that baby has smith-lemli-optiz?

Hello dr I did a screening test for safety of baby the test was negative but they writ that it will have a risk 1/25 that baby has smith-lemli-optiz?

Complex issue: If a woman is tested with an increased risk for Smith Lemli Opitz syndrome a consultation with a Medical Geneticist may help to better understand the nature of the disease. ...Read more

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What's a urine cannabinoids screening test?

What's a urine cannabinoids screening test?

Drug test: This is a laboratory test which analyzes the concentration of marijuana products in the urine. Some consider this an invasion of privacy, but some industries require this as a screen for employment. This falls under the political issue of whether these substances are a serious problem or not. ...Read more

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Why is a triple screening test done?

Why is a triple screening test done?

Fetal defects: Triple screen is a screening test for fetal disorders, such as neural tube defect, and down syndrome. ...Read more

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Is there a mental screening test type?

There are many: Many screening tools are available to assess mental health. Survey tests help identify dementia, bipolar disease, attention deficit disorders and others. Generally these are used when there is a worry about a particular problem, but there is good evidence that all adults should be screened for unrecognized depression. For more info on proven screening tests, check out the Prevention Checklist app. ...Read more

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Do I need to have down's screening tests?

Screening can help: There is no requirement for a patient to have an invasive diagnostic test like amniocentesis to determine if a fetus has trisomy 21. However, most OB providers offer the screening test to pregnant women. Both should be accompanied by counseling so that couples can discuss them and the pregnant woman can decide what testing, if any, to undergo. ...Read more

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Are down's syndrome screening tests accurate?

Are down's syndrome screening tests accurate?

Yes: Amniocentesis is 100% accurate. The blood test screening tests are 85-95% accurate. ...Read more

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Which screening tests are don't for women and men?

Which screening tests are don't for women and men?

Many: There are many recommended tests including cholesterol blood tests, colon / breast / cervical cancer screening, tests for depression, obesity, osteoporosis, and abdominal aneurysm. There are other recommendations, too. For a complete list of preventive recommendations by age/gender and risk factors (if you have an ipad/ipod/ipad see the prevention checklist 2013 app. ...Read more

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Where can I find the most accurate screening tests?

Excellent question: All tests have some false positive and some false negative results, but you are right - some are better than others. The ones that are recommended by reliable sources are the best that we have. For a complete list of recommended screening tests by age, gender, and risk factor, look at the prevention checklist 2013 app. ...Read more

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What screening tests do newborns get?

What screening tests do newborns get?

Blood and hearing: Around 24 hours old babies should have blood drawn for a newborn screen and bilirubin. The newborn screen is a test that looks for genetic and metabolic diseases (the number of diseases tested varies by state). The results usually come back in 3 weeks. The bilirubin will come back in a few hours and is a measure of jaundice in the baby. Newborns also get a hearing test before hospital discharge. ...Read more

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How to pass an etg alcohol screening test?

How to pass an etg alcohol screening test?

Stop taking alcohol: For at least a week before the test. Do not even use alcohol sanitizer gels. ...Read more

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Is it necessary to do prenatal screening tests?

Maybe not: Prenatal testing is usually for the parents, peace of mind and intervention. There are a growing number of conditions that intervention can improve outcomes. More often parents are challenged with the? Do I continue this preg? If you understand the risks and you know you would not terminate the preg, no matter what, you do not have to test. ...Read more

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I've had positive HIV screening test> im scared can anyone help?

I've had positive HIV screening test> im scared can anyone help?

Talk to an expert: There are a number of tests to find out whether a person is infected with hiv. Tests include: HIV antibody; p24 antigen; pcr. Once diagnosed with the virus, CD4 and viral load test is done. If you indeed had a "screening test, " there is a chance that the result was a "false positive." confirmatory testing may be necessary. If it is positive-contact a professional counselor for emotional support. ...Read more

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What are the common screening tests for the diagnosis of cancers?

What are the common screening tests for the diagnosis of cancers?

Many: It depends on your age and gender. At age 40 women should get pap tests for cervical cancer and consider mammograms for breast cancer. There are no proven routine cancer screening tests for men at that age. Sometimes other tests are recommended if high risk. For a complete list of proven screening tests, vaccines and other ways to stay healthy, check out the Prevention Checklist iPhone/iPad app. ...Read more

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What are the most accurate psychiatric illness screening tests available?

Psychiatric illness: The most important diagnostic tool is face to face clinical interview with a psychiatrist, you can get second or third opinions.
Different scales for depression, anxiety, bipolar, psychosis can be used.
Also, tests like mmpi, mcmi help differentiate axis 1 and axis 2 with certain validity levels. ...Read more

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On the Down syndrome screening test my due date was miscalculated. Does it matter?

On the Down syndrome screening test my due date was miscalculated. Does it matter?

Several test types: There are several types of testing availble, from sonogram, chromosomal testing from chorionic villus or amniocentesis and new blood tests. A small difference in fetal age will not likely invalidate all of the tests. ...Read more

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What would you say are most accurate psychiatric illness screening tests one can find online?

What would you say are most accurate psychiatric illness screening tests one can find online?

DSM V is out soon.: Dsm v has the complete categorical criteria for psychiatric diagnoses. It will be available next month, replacing dsm iv. However one should never engage in self diagnosis but see a trained professional to verify any concerns that you have. ...Read more

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Can you tell me if on a random drug screening test what will show up false positive for a diabetic?

Can you tell me if on a random drug screening test what will show up false positive for a diabetic?

Probably not but. ..: What is being looked for is the value of the glucose in the blood at that moment that the blood is drawn. It is very specific for the amount of glucose. If you ate a food containing glucose or another carb which could be converted to it not too long before the blood was drawn then the value of the glucose would rise. A better test which looks back 90 days is Hemoglobin A1c. ...Read more

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I'm 62yo/fem. My sister had died of ovarian ca in 1987. should I get screening tests for myself? Which ones and how often?

I'm 62yo/fem. My sister had died of ovarian ca in 1987. should I get screening tests for myself? Which ones and how often?

Ovarian cancer: Early ovarian cancer can be difficult to diagnose so when there is concern for the possibility of the diagnosis eg. Due to family history, it is wise to see a gynecologist for an examination and follow up regularly. ...Read more

Dr. Jeffrey Stevens
1 Doctor shared a insight

Screening (Definition)

Examples are: colonoscopy for colon polyp or cancer; mammograms for breast lesions or cancer; psa a blood test that could indicate enlargement of cancerous prostate tissue; blood sugar or hemoglobin a! c for diabetes. Many think that scanning the whole body will pick up a cancer--in all likelihood, it will not. There also is no good blood test, yet, ...Read more