Doctor insights on:
Ms Relapse Remitting
RRMS: Relapsing-remitting MS is the most common form of MS. In this, there are episodic "attacks" or relapses of symptoms interfering with neurological function. These could affect vision, movement, sensation, speaking, coordination, bowel or bladder function, etc. Normally these attacks last 2-3 days. They often are treatable and the symptoms resolve. ...Read moreSee 4 more doctor answers
Stay tuned: Stay tuned! this field is changing rapidly. Whereas injectable medications are the first tier of therapy, we are entering an era of oral medications and infrequent infusion therapies. Choosing the right therapy from this more and more crowded field of contenders will only get more complex. An MS specialist can help guide the discussion so that individuals can make the best informed choice. ...Read moreSee 3 more doctor answers
Was on many medications for confirmed MS (rebif, copaxone, gilenya, tysabri, (natalizumab) tecfidera) none helped control.. Is this typical of ms? Next step?
Unusual but possible: Visit an ms center.Get a more detailed answer ›
How to diagnose MS: There are MS symptoms, and then there are symptoms that help to make the diagnosis of MS. For example, muscle spasm is a symptom of MS, and many other illnesses. Lesions of the brain are caused by MS, but also by viruses, head injuries, etc. If you have the right symptoms and the right MRI findings, the diagnosis should be clear. With MS, the diagnosis is rarely that easy to make. ...Read moreSee 2 more doctor answers
TTP/rituximab: Twelve articles have reported 27 patients treated with Rituximab for ttp, with bene?t described in 25 (93%) of the patients. These observations from small uncontrolled case series is said to provide the background and rationale for a randomized clinical trial to establish the efficacy of Rituximab in this disease. ...Read moreSee 1 more doctor answer
Risky idea: If you stop your infusions abruptly, and do not replace with a potent ms agent such as gilenya, you will be at very high risk for a relapse, and a substantial rebound of the disease, at about 3 months. If you do have a positive anti-jcv antibody test, you and your doctor might decide to stop tysabri (natalizumab) by 18-24 months, but you need to start a new medication. Discuss with your neurologist. ...Read more
For Neurologist with sizeable Tecfidera MS pt load...Acute eosinophilia 1.4/12% 3wks on Tecfidera w/o new Sxs. What "transient increase"s have u seen?
Experiences: First, am not enamored with Tecfidera, as over 20% of my patients have found it intolerable due to GI adverse events, and many have found it to be ineffectual. Can cause drops in lymphocytes and also affect other white cells, and your eosinophil elevation could very well represent a low level allergic response which may depart in a few weeks. Clarify the issues with your neurologist. ...Read more
No: ? Whether fibromyalgia (FM) is "forever progressive". FM multifactorial & causes can vary from person to person. Deconditioning, weight gain, sedentary lifestyle, & multiple mechanical injuries seem to worsen prognosis. Those persons who improve do so by avoiding injuries, losing weight, & increasing gentle physical activity via yoga, walking & aquatherapy; also optimum nutrition, massage... ...Read moreSee 2 more doctor answers
CSF says "mature lymphocytes" present. Also 5 OCBs. 4cm brain lesion, persistent enhancement, relapsing remitting symptoms. 5 years trying to dx. ?
Not finished: You only present half the story, not the full feature. It is tempting to blurt out "MS" with 5 OCB, but there are other autoimmune disorders that are more rare. NOBODY (in my opinion) has a stronger autoimmune Neurology program than Mayo. If its been five years, no diagnosis, time to see an institution of that power. ...Read more
Multiple myeloma patient relapsed after Velcade , Revlimid (lenalidomide) and Carfilzomib. Any hope. Patient is 80 yrs old?
Help.Lupus-like condition.Get flares of severe brain fog, confusion, dizziness -affects my job.Neg neuro work-up.Increasing prednisone during episodes& symptoms resolve.Lupus cerebritis still likely?
Rheumatologist: You must be seeing a physician for this condition. Have them consider consultation with a neurologist. While on steroids you are at significantly greater risk for central nervous system and other infections. Cannot advise more without knowing your full medical history. ...Read moreSee 1 more doctor answer
A friend had chronic demyelinating polyneuropathy (cidp), then got chronic lymphocytic leukemia 2 years later. Is cidp paraneoplastic syndrome sometimes?
Not likely: Chronic inflammatory demyelinating polyradiculopathy (cidp) is almost always an autoimmune condition incited by some antecedent infection--c. Jejuni, ebv, cmv, or another infection. Antibodies produced against the virus/ bacteria/ pathogen cross-react with the myelin sheath on the nerve roots, first causing guillain-barre (aidp), then later cidp. It's exceedingly rare that cancer could cause this. ...Read moreSee 2 more doctor answers
See below: Secondary progressive MS is a more advanced stage of relapsing remitting ms. In this stage, individuals experience fewer recognized neurological relapses, and betwen such attacks begin to accumulate measureable worsening of physical or cognitive disability. It is not a distinct form of disease, but part of the spectrum of relapsing ms. ...Read moreSee 2 more doctor answers
Have undifferentiated ctd.My rheummd strongly believes I have CNS involvement-confused, fog, dizzy, headache.Resolves w/ high doses prednisone.Prognosis?
Depends on control: Depends on control - and side effects of medicine used in control and on more specific diagnosis. ...Read more