Doctor insights on:
Ms Contin Overdose In Children
MS Contin: Ms Contin is a sustained release formulation of morphine. If crushed it can lead to sudden delivery of all the drug in short time and may cause overdose. It is a relative term as people who are accustomed to it can tolerate very high doses but people naive to opiates may get overdosed with a small amount.. ...Read more
Which has a higher risk of fatality? Accidental overdose of MS contin (morphine) sr 30mg or percocet 10mg?
Neither: At the stated levels, fatality would be unusual with either drug alone if the individual had no other medical issues. Unfortunately, most overdoses occur with multiple other drugs such as the benzos like xanax (alprazolam) or valium combined with alcohol.These combination are frequently implicated in fatal overdoses. ...Read more
Normal dose: There is no such thing as a normal dose. There is a notion of "clinically accepted dosing" but this also variable. The correct way to look at this - is this dose effective - if yes then its fine, if no they it needs to be adjusted. ...Read more
Forever: Although chronic opiod ingestion can cause hormonal abnormalites and depression, so can chronic pain. The morphine itself has no long term adverse effects on any organ system other than endocrine effects. Constipation is the only GI effect that is pretty consistent. I have patients that have been on morphine for 15 years without any consequences other than above which are treatable. ...Read more
OxyContin: Oc (extended release oxycodone) is stonger by a factor of almost twice-that is 15 mg of oc is about equal to 30 mg of MS contin (extended release morphine sulphate). But there is a lot of variability between individuals. Oc seems to be more energizing for some patients and as a result there is more "liking" which is independent of the pain relief. That may explain why there seems to be more abuse. ...Read more
MS Contin (morphine) = oramorph: There is no such thing as "stronger" or "weak" opioid medication, only those that work and don't work, based on the patient's individual circumstances and genetics. ...Read more
Better?: Both medications are classified as opioid analgesics meaning they are derived from opium. Ms contin (morphine) is an extended release formulation indicated for constant, chronic pain. These medications should only be prescribed for severe pain. The longterm use of these medications is controversial and should be done under the direction of a qualified physician. ...Read more
Normal dose: Adults—10 to 20 mg every 4-6 hours as needed. Your doctor may adjust your dose even higher, if needed. ...Read more
Duration of Action: Kadian seems to reliably work for 12 to 24 hours for "tolerant" patients. Ms conting lasts only 6 to 8 hours and is seldom dispensed by pharmacies due to the multiple companies making a generic version. The generics have even more variabilty in their duration. Kadian uses a delivery mechanism that is more reliable over a longer period. They both contain morphine as the active drug. ...Read more
No direct effects: Could worsen Insulin overdose or ketoacidosis from extremelyy high blood suger but wouldn''t cause either of these conditions. It would occur by causing more sedation and be additive to the sedation caused by these conditions. ...Read more
Same as anyone else: If the diabetic is prone to very low or very high blood sugars, the morphine may increase the sedation or even cause unconsciousness. For the pain that comes from nerve damage from diabetes, there may be other classes of meds that work better without as many side effects. ...Read more
Can you tell me if a type 1 diabetic person takes MS contin, (morphine) can it affect the person?
How do you know what dose of MS Contin (morphine) is needed? Is it the total amount of Oramorph used daily?
Depends on type: This is a question that should be answered strictly by your prescribing physician. Oramorph has a diff dosing sched than Oramorph SR. In general, total amount of morphine used per day should be equivalent. Ex. if you require 30 mg of Oramorph per day to adequately control your pain, the dosage of MS Contin should be 30 mg. Some drs., though give a specific amount of MS Contin w/a smaller rescue dose. ...Read more
No: It's the other way around - oxycodone is 3 to 5 times more potent than morphine, but in equipotent doses, they have the equivalent effect. "strength" is not a characteristic that means better or worse, it's the size of the pill or the shot. When drugs are given in equivalent doses, they work about the same, although there are individual differences in side effects and other characteristics. ...Read more
Sometimes: MSContin is far better for most types of chronic pain than any of its shorter-acting relatives.Nerve modulators like Lyrica (pregabalin) & Neurontin can also be helpful. All work on the theory that pain is primarily in the brain. In my practice, pain almost always has an actual mechanical or inflamm. Cause which is treatable w/ osteopathic manip., neuroprolo, Vit D/glucose creams, etc. This is 'cure' v 'control'. ...Read more