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Doctor insights on: Mother Father Thalassemia

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If the mother is alpha and father is beta thalassemic, can their children be free from thalassemia?

If the mother is alpha and father is beta thalassemic, can their children be free from thalassemia?

Only if traits: If mom and dad are both thalassemia trait, not "major", then mom and dad most likely each have one normal gene. The child who inherits the normal gene from mom and from dad, will end up with 2 normal genes and no thalassemia! ...Read more

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Dr. Michael Engel
270 doctors shared insights

Thalassemia (Definition)

An inherited condition ...Read more


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If one parent has hb e beta thalassemia and the other is normal, is their child can get disease?

If one parent has hb e beta thalassemia and the other is normal, is their child can get disease?

No: The normal parent will give his or her normal gene to their baby. That means the baby will have one abnormal and one normal gene, meaning the baby would be a "carrier" of one bad gene and not suffer the actual disease. The only way the baby would end up with 2 abnormal genes is if the gene from the normal parent got altered by a new mutation... Which is unlikely to happen. ...Read more

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If one parent has beta thalassemia, what are the chances that their baby could inherit the condition?

If one parent has beta thalassemia, what are the chances that their baby could inherit the condition?

Depends: If one parent has beta thalassemia major, and the other parent has none, then their children should all be carriers. If the other parent is a carrier then about half their children will be carriers and half have disease. If one parent has beta thal minor (carrier), and the other parent has none, then about half their children will be carriers and half will be normal. A geneticist can give details. ...Read more

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Have chest pain burning and heavy, heart pounds and races have Thalassemia unknown type from 1 parent what could be wrong, have had xray EKG bloodtest?

Have chest pain burning and heavy, heart pounds and races have Thalassemia unknown type from 1 parent what could be wrong, have had xray EKG bloodtest?

Burning chest: Burning chest pain could arise from GERD (heart burn), lung or airway problems, muscle or bone problems. What causes your symptoms to occur? How long do they last? It is important to think about the heart as the source of the symptoms, but there are other sources too. ...Read more

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I have Thalassemia from my mother does b12 deficiency make it worst and how?

See below: B 12 is essential for normal function of bone marrow and red cell production. B12 deficiency will make anybody worse, with or without thalassemia.. For good health - Have a diet rich in fresh vegetables, fruits, whole grains, milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Drink enough water daily, so that your urine is mostly colorless. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form. Practice safe sex, if you have sex. ...Read more

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If father's blood is a and mother is o, can a child be b?

If father's blood is a and mother is o, can a child be b?

No.: Except for very rare cases of mosaicism (two gene lines in the same person) this is not possible. ...Read more

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If the mother has a+ blood, and father has a-, what will the child have?

If the mother has a+ blood, and father has a-, what will the child have?

Blood type: To be a+ you can have 1 gene a+ and the other a- or both genes a+. To be a- you have both genes a- . So the baby can be a+ (1 gene a+ and the other a-) or the baby can be a- ( one gene a- and the other a-). ...Read more

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Can a brown eyed father and a blue eyed mother still have a blue eyed baby?

Can a brown eyed father and a blue eyed mother still have a blue eyed baby?

Sometimes: Brown is the dominant gene, but if i remember from my high school science class, you can have a recessive gene for blue eyes, so the chance of having a blue eye baby if the mother is fully recessive for blue but the dad is partially recessive for blue, is actually 50%... However, if the father has both dominant gene for brown, then no. ...Read more

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Mother with ncah and father is a carrier. What can be done to stop future children having the disease?

Mother with ncah and father is a carrier. What can be done to stop future children having the disease?

Genetic referral: Make an appointment to see a geneticist and review your options. This is a difficult situation. ...Read more

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If grandfather rh- grandmother rh+ ; mother + father both rh+; what is the chance of grandchildren being rh-?

If grandfather rh- grandmother rh+ ; mother + father both rh+; what is the chance of grandchildren being rh-?

Can't answer: This isn't the best venue for homework help, and since you have not told about the other set of grandparents, and since we have no way of knowing whether the rh-positive grandparent is homozygous or heterozygous, the question isn't answerable. ...Read more

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If mothers blood group is rhs O neg and baby blood group is O positive what would the fathers blood group be?

If mothers blood group is rhs O neg and baby blood group is O positive what would the fathers blood group be?

Father's blood type: Father is O positive. In the A-B-O nomenclature, A and B and dominant and Rh + is dominant over Rh -. That means that the baby had to get an O allele from both mother and father and at least one Rh + allele from a parent. Mom is OO neg neg and that means that the father has to be OO pos neg or OO pos pos. Either way, the father is phenotypically O pos. ...Read more

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What are my chances of having diabetes when my mother's father (and his brother) and my father's mother have it?

What are my chances of having diabetes when my mother's father (and his brother) and my father's mother have it?

Risk factors: Family history contributes to risk for diabetes, but lifestyle is also important. You can lower your risk for developing diabetes by maintaining normal weight, getting sufficient sleep, exercising regularly, and eating a diet rich in fresh fruits vegetables and whole grains. ...Read more

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My father is A+, my mother is A-. My Mother is rh negative. Im trying to make sense of things. Im A- rh negative. Is this possible?

My father is A+, my mother is A-. My Mother is rh negative.
Im trying to make sense of things. Im A- rh negative. Is this possible?

Yes: That sounds fine. In such a scenario, if you had many siblings, some would be Rh positive and some would be Rh negative. ...Read more