Doctor insights on:
Most Effective Statin With The Fewest Side Effects
Several drugs exist which lower cholesterol by inhibiting an enzyme in liver cells (hmg-coa reductase) that is involved in cholesterol synthesis. These all have generic names that end in -statin, e.g. Atorvastatin (lipitor) and Simvastatin (zocor). Since nearly all of the meds in this class have been shown to have similar cardiovascular benefits, we often discuss them ...Read more
Yes: The most common side effects from statins include 1) myalgia and increased CPK from skeletal muscle and 2) elevated liver function tests reflecting liver inflammation. A vast majority of these side effects are benign. There have been instances of severe skeletal muscle damage or severe liver damage but these episodes are very unusual. ...Read moreSee 1 more doctor answer
Liver and myalgias: Statins are beneficial in both primary and secondary prevention of CAD in high risk patients including diabetics. The biggest concern with using them involve a 5-10% incidence of myalgia. Liver enzyme elevation ( >3x normal) occurs 1% of the time. These side effects reverse with cessation of the statin.Dangerous side effects like rhabdomyolisis are rare (1 in several thousand patients). ...Read more
Yes: You may simply stop. There is no need to wean statin medications. ...Read more
Took statin drugs 9 years side effects made me stop the drug will the 9 years i was on statins be a credit when i get into my 70s and 80's?
Cholesterol karma: Lets start by saying statins simply control a risk factor (hypercholesterolemia). There is no evidence that they extend your life. The more important question would be, what are your current risk factors? Are you eating right? Exercising? Whats your bmi. What's your blood pressure? What's your cholesterol now? Talk to your doc. They can assess your risks and set you on the right course if action. ...Read more
Bit diverse: Statins have been getting a bad RAP re: adverse effects. Many symptoms are attributed to statins, but often are not truly related. Muscle aches of a certain type, abnormal liver function tests, vague abdominal discomfort, minor elevation of blood sugar levels, may be noted. Key things to note are that these symptoms & signs are actually uncommon & tend to be dose dependent. Reducing dose helps. ...Read more
Statin side effects: Hopefully you will have none! most people do not. I find zocor (simvastatin) or Simvastatin to have the most. Leg cramps are common with this one along with muscle aches. Sometimes coq 10 helps these side effects. Grapefruit juice should be avoided since it can increase blood levels of some of the statins. You should really have a discussion with your doc since many of the statins are now generic and cheap. ...Read more
Is there any advantages with
taking statins compared to an alternate ie fabrizate
as not everyone is convinced by Statins due some side effects?
Pleotropic benefits: Statins have been around since the 1980s and there is lots of evidence that independent of their lipid lowering benefit, they are anti-oxidants, stabilize endothelium and are anti-inflammatory. They significantly reduce ones risk of an adverse cardiovascular and cerebrovascular event for these reasons in addition to reducing cholesterol numbers. ...Read more
Lessen you dosage: Consult with your doctor. The rx instructions indicate a reduction of dosage is in order under the guidance of your doctor. A pill splitter can cut the pills in half to give you half dose. You can eliminate certain days a week to cut your overall dose. I know a person that reduce their dose to taking only 5 mg once per week - approved by their doctor, and is doing well.. ...Read more
Yes most of the time: Drs use these drugs to reduce the cholesterol and reduce cardiovascular events in certain high risk populations. Its side effects are monitered by your doctor. Labs for liver enzymes and muscle damage are drawn on a regular basis. Its a safe drug used over a long time period if used properly. Like anything else risk vs benefit should be evaluated when starting a pt on a medicine. ...Read more
43y/o male 6' 175lb had cto LAD stented. LDL little high but lpa high, 120mg/dl. how to lower lpa? having rough time w/ statins side effects.
Niacin: Although LPa is an established risk factor for coro art disease it is unclear wether treating it leads to reduce cardiac events unlike lowering LDL.Niacin is the only known medicine to lower LPa It also lowers LDL and triglyceride. If you absolutely is intolerant to statins ,Niacin maybe an alternative,that is if you can take it which a few people can't ...Read more
What other options does someone have who has hyperlipidemia but has statin intolerance? BTW CoQ10 does nothing to help with the statin side-effects.
Usually none: But muscle effects should be closely monitored. ...Read more
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