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Doctor insights on: Most Effective Antihistamine

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What is the most effective antihistamine antihistamine with anti emetic properties?

What is the most effective antihistamine antihistamine with anti emetic properties?

Usually not: Antihistamine has minimal effect on vomiting although Phenergan (promethazine) may provide mild benefits. Zofran will likely be more effective. You need to find out what may be causing your vomiting first. ...Read more

Dr. Paul Carter
601 doctors shared insights

Antihistamine (Definition)

Sedating and non-sedating antihistamines prevent and treat allergic reactions, and are ...Read more


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I have allergy symptoms year round and the biggest concern is constant post nasal drip, what is the most effective antihistamine for post nasal drip?

I have allergy symptoms year round and the biggest concern is constant post nasal drip, what is the most effective antihistamine for post nasal drip?

Nasal steroid: Nasal steroid will likely be more effective than any antihistamine. However one needs to rule out sinus infection as the cause also. If nasal steroid did not affect your drips after a week of daily use, consider seeing an allergist. ...Read more

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Are first generation antihistamines more effective than second generation? I always wonder why some are still on drugstore shelves, like chlorpheniram

Are first generation antihistamines more effective than second generation? I always wonder why some are still on drugstore shelves, like chlorpheniram

Less side effects: There are many medications that remain on shelves for over-the-counter use that probably should be removed. New generation antihistamines are as effective as old ones. Of interest is that some individuals respond favorably to one over the other. The side effect profile and frequency of dosing is what really separates the new from the old antihistamines. In this case, newer is better. ...Read more

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What antihistamines work the fastest and are most effective ? With the tablets do you chew them or take with water ?

Antihistamines: Most antohistamines work wothin 30-45 minutes, if taken orally it does not speed their effect, either chewed or swallowed, mit is faster if given intravenous. ...Read more

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Any effective OTC alternatives to oral antihistamines?

Any effective OTC alternatives to oral antihistamines?

Antihistamine picks: To answer this we need to know what symptom you want the antihistamine to treat. If you want to stop itching, oral steroids can be used, they are very strong and work well but have loads of side effects and dangers. For a runny nose from allergies, nasal antihistamine or corticosteroid sprays are more effective; montelukast can also be tried. None of these are otc, though. ...Read more

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Are alternatives to oral antihistamines more effective or less effective?

Are alternatives to oral antihistamines more effective or less effective?

Antihistamine picks: To answer this we need to know what symptom you want the antihistamine to treat. If you want to stop itching, oral steroids can be used, they are very strong and work well but have loads of side effects and dangers. For a runny nose from allergies, nasal antihistamine or corticosteroid sprays are more effective; montelukast can also be tried. For sleep at night, other meds may work better...Etc. ...Read more

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How effective are antihistamines for treating chicken pox?

How effective are antihistamines for treating chicken pox?

Only for Itching: Antihistamines are used to stop the itching due to rash of chicken pox and only help itching symptoms It does not alter the course of the disease itself ...Read more