Doctor insights on:
Most Aggressive Types Of Cancer
Stage 4 cancer: Most stage 4 cancers are not curable. Stage 4 (or metastatic cancer) is when cancer has travelled to a distant place in the body. There are a few exceptions: many stage 4 testicular cancer or lymphoma may be curable. For stage 4 melanoma, a small percentage of patients may be cured with immunotherapy such as interleukin-2 or ipilimumab. ...Read more
Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more
Absolutely: The more bizarre the tumor (poorly differentiated or undifferentiated) the more aggressive it would be, as a rule. Now, every patient and their cancer has their own relationship, and there are no absolutes. Your oncologist and/or surgeon can discuss the behavior of your cancer, but it's hard to be specific. Good luck. ...Read more
Low doses of: Diagnostic radiation (like mammograms, chest x-rays) may be exceedingly rare causes. We know that XRT for hodgkin's in young woemn led to excessive risk of breast and lung cancer, and we now use it more sparingly and to lower volume and doses if at all. Even low doses for children to prevent brain relapse in leukemia has been linked to excess brain tumors. But second tumors do not occur in all. ...Read moreSee 1 more doctor answer
A lot: The FDA has approved a large number of targeted therapies. These therapies target specific proteins on the surface of cancer so each therapy can be applicable to multiple types of cancers. So far, cancer amenable to targeted therapy include: adenocarcinoma, basal cell, brain tumors, cervical, colorectal, head/neck, gastrostromal, kidney, leukemia/lymphoma, lung .... The list goes on. ...Read more
Several: All but the most localized cases of hodgkin's, osteosarcomas, ewings', and embryonal cell carcinoma of the testis, and all choriocarcinomas and pediatric leukemias, were the kiss of death until chemotherapy. Today we expect cures in the majority of these cases using chemotherapy. This is in contrast to most lung, breast, colon, prostate, stomach, brain where chemo may give time but no cure. ...Read more
Testicular Cancer: The most common cancer is a second testicular cancer in the opposite testicle. Also depending on whether one receives chemotherapy or radiation, and to what areas, there may be increased risk of secondary cancers (leukemia from chemotherapy, sarcoma from radiation). ...Read moreSee 1 more doctor answer
All leukemia types..: may be cured in some people but not in others. Factors which make leukemia very high risk and less likely to be cured include certain chromosomal aberrations, abnormal (dysplastic) shapes of the leukemia cells, and old age of the patient. To be more precise one must first determine which kind of leukemia we are dealing with. ...Read more
Varies: Some cancers are not detected until widespread and it is too late to intervene. The real question is why? Some may not present with early symptoms because of their "silent" location. For example, pancreatic cancer off of the tail of the pancreas grows, spreads and seeds the abdomen with minimal symptoms. Some cancers of the GI tract are found on screening tests.When symptomatic, it is too late. ...Read more
Yes: Yes. In general, we think most colon cancers take about 10 years to develop. Hence, the guidelines for colonoscopy every 10 years if a "normal" colon is found. However, some familial syndromes result in faster polyp and cancer growth. Also, some individuals may have more or faster growing polyps or cancers. A gastroenterologist should be able to help individualize a surveillance program. ...Read moreSee 1 more doctor answer
All: Dr. Singh is correct. When i was a kid, we cured 2 out of 6 cancers (excepting the common non-melanoma skin cancers, which are easily managed). When i was in med school, it was 3 of 6; now it is 4 of six. "cancer is a word, not a sentence." be vigilant, avoid tobacco, and get seen early if you have any signs. ...Read moreSee 1 more doctor answer
Many diff regimens: There are many different regimens utilizing multiple drugs and ranging 3-6 months. Common drugs are anthracyclines, taxanes, and Cytoxan (cyclophosphamide) in various combinations - acx4, tcx4(or 6), tac x 6, acx4 ->tx4, dose dense ac->t, weekly taxol. Other options/drugs can also be considered in the metastatic setting. A patient should seek a medical oncologist experience in breast to rec the best regimen. ...Read moreSee 1 more doctor answer
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